Future copper metallurgy for the age of e-mobility and the circular economy. Copper, nickel, cobalt, chromium and tin metals are essential for the manufacture of new battery materials, electrical and electronic devices and technologies that will enable the global transition to sustainable energy systems. There are major technical challenges associated with the industrial scale high temperature production, separation and recycling of these metals. The aim of the present study is develop advanced ....Future copper metallurgy for the age of e-mobility and the circular economy. Copper, nickel, cobalt, chromium and tin metals are essential for the manufacture of new battery materials, electrical and electronic devices and technologies that will enable the global transition to sustainable energy systems. There are major technical challenges associated with the industrial scale high temperature production, separation and recycling of these metals. The aim of the present study is develop advanced chemical thermodynamic databases and models that can be used to predict the outcomes of these complex chemical reactions, and in doing so provide the industry with the vital fundamental scientific information and tools needed to be able to design and improve new, more efficient metal production and recycling technologies. Read moreRead less
Sustainable copper metallurgy and recycling – saving energy and resources. This project aims to develop new, powerful and sophisticated, computer-based models that can reliably predict the results of chemical reactions in complex, high temperature metal production processes. This project expects to use these models, initially applied to copper smelting systems, to enable the improved recycling of other valuable metals. These models should be able to be applied to a wide range of technologies use ....Sustainable copper metallurgy and recycling – saving energy and resources. This project aims to develop new, powerful and sophisticated, computer-based models that can reliably predict the results of chemical reactions in complex, high temperature metal production processes. This project expects to use these models, initially applied to copper smelting systems, to enable the improved recycling of other valuable metals. These models should be able to be applied to a wide range of technologies used in the metallurgical industry as most of the world’s metals are produced by these pyrometallurgical processes. This should provide significant benefits such as substantial improvements in productivity and process efficiencies, whilst at the same time delivering energy savings and improved use of valuable metal resources.Read moreRead less
Creating wealth from new resources - High temperature extraction of metals from complex copper ores and recycled materials. Most of the world’s copper is produced using high temperature chemical processing (smelting). Both primary ores and recycled raw materials contain valuable elements and also potentially harmful impurity elements. To unlock and utilise current and new resources, and also minimise the environmental impacts the industry has identified the need for new fundamental scientific da ....Creating wealth from new resources - High temperature extraction of metals from complex copper ores and recycled materials. Most of the world’s copper is produced using high temperature chemical processing (smelting). Both primary ores and recycled raw materials contain valuable elements and also potentially harmful impurity elements. To unlock and utilise current and new resources, and also minimise the environmental impacts the industry has identified the need for new fundamental scientific data that describe the chemical behaviour of impurity elements in these systems. The project aims to then use the data to develop powerful computer-based thermodynamic models that can predict the products of complex industrial processes. These sophisticated tools are intended to then be used to improve the performance of existing industrial operations and assist in the development of new process designs.Read moreRead less
Future polymetallic processing through lead smelting, recycling, refining. The aim of the project is to provide new data and thermodynamic modelling tools to be used in the development of the next generation of lead metal smelting, refining and recycling processes used to recycle electronic materials, process hazardous wastes and recover valuable metals. The intention is to combine recently developed experimental techniques with the latest advances in FactSage chemical thermodynamic modelling to ....Future polymetallic processing through lead smelting, recycling, refining. The aim of the project is to provide new data and thermodynamic modelling tools to be used in the development of the next generation of lead metal smelting, refining and recycling processes used to recycle electronic materials, process hazardous wastes and recover valuable metals. The intention is to combine recently developed experimental techniques with the latest advances in FactSage chemical thermodynamic modelling to overcome long-standing experimental and modelling obstacles. The new experimental data and databases are intended to provide important information on high-temperature chemistry of complex phase equilibria and on the distribution of minor elements in multiphase systems.Read moreRead less
Thermodynamic basis for ironmaking and slag recycling in circular economy. This project aims to develop new, powerful state-of-the-art computer-based tools to predict the outcomes of complex chemical reactions, high-temperature ironmaking and slag recycling processes. Globally, over 1 billion tonnes of iron are produced each year consuming 30 billion billion (Quintillion) Joules energy! and creating over 300 million tonnes of molten oxides (slags). Our industry partners need new advanced thermod ....Thermodynamic basis for ironmaking and slag recycling in circular economy. This project aims to develop new, powerful state-of-the-art computer-based tools to predict the outcomes of complex chemical reactions, high-temperature ironmaking and slag recycling processes. Globally, over 1 billion tonnes of iron are produced each year consuming 30 billion billion (Quintillion) Joules energy! and creating over 300 million tonnes of molten oxides (slags). Our industry partners need new advanced thermodynamic databases and computer models with which to optimise their major industrial processes and develop new technologies. By delivering these tools, this project expects to benefit both industry and the community through improved process efficiencies, and reductions in energy usage, pollutants, and environmental impacts.
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Microstructure control of hot-dip coated Al-Zn based alloy layers on steel . The process of hot-dip metal coating of steel has evolved to provide reliable products that find widespread application in many industries, including building and construction. This project aims to address and understand an intermittent processing problem using innovative approaches involving characterisation by synchrotron techniques and state-of-the art microscopy. Expected outcomes include increased manufacturing e ....Microstructure control of hot-dip coated Al-Zn based alloy layers on steel . The process of hot-dip metal coating of steel has evolved to provide reliable products that find widespread application in many industries, including building and construction. This project aims to address and understand an intermittent processing problem using innovative approaches involving characterisation by synchrotron techniques and state-of-the art microscopy. Expected outcomes include increased manufacturing efficiencies by identifying the cause of an intermittent processing defect and implementing methods of controlling this defect. This will help BlueScope and Australia maintain a world-leading reputation for high-quality coating products for domestic and export markets.Read moreRead less
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing an ....Data-driven monitoring of raceway dynamics in ironmaking blast furnaces. Raceway dynamics in ironmaking blast furnaces affect operational stability and cost considerably, yet their dynamic behaviour has not been well monitored online. The project aims to develop a data-driven model for monitoring the internal state of gas-solid-powder reacting flow in the raceway and predicting raceway anomalies online. It will be achieved by combining particle-fluid numerical simulations with data processing and reduced-order state observer, supported by lab/plant experiments, and collaborating with two industry partners from coal and steel industries. The project outcomes including codes, models and raceway control strategies can help promote Australian metallurgical coal's global markets and ultimately the Australian economy.Read moreRead less
Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease. Through the combination of expertise from the Industry partner and the Hume group this project aims to develop specific inhibitors of the CSF-1 receptor protein tyrosine kinase in order to demonstrate their efficacy as modulators of CSF-1 dependent macrophage and tumour cell function in vitro. The expected outcome will be a lead set of targets which can be further assessed for therapeutic pote ....The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease. Through the combination of expertise from the Industry partner and the Hume group this project aims to develop specific inhibitors of the CSF-1 receptor protein tyrosine kinase in order to demonstrate their efficacy as modulators of CSF-1 dependent macrophage and tumour cell function in vitro. The expected outcome will be a lead set of targets which can be further assessed for therapeutic potential in clinical trials.Read moreRead less