ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Targeted mining for new drugs against parasitic nematodes of animals - a synergy of integrated, frontier technologies and a committed partnership with industry. This project will: develop a quality scientific and technological program in national priority areas, leading to a strong basic research, new concepts and the enhanced international collaborative links; strengthen links between basic and applied research, and academia and industry; develop excellence via pan-Australian collaborations, re ....Targeted mining for new drugs against parasitic nematodes of animals - a synergy of integrated, frontier technologies and a committed partnership with industry. This project will: develop a quality scientific and technological program in national priority areas, leading to a strong basic research, new concepts and the enhanced international collaborative links; strengthen links between basic and applied research, and academia and industry; develop excellence via pan-Australian collaborations, resulting in a more efficient use of resources in a national and international context; enhance the skills-base in biology, biotechnology and bioinformatics; increase global visibility with increased investment in Australian science; improved animal welfare and production via better control of infectious diseases; commercial products with benefits to agricultural producers in regional and rural communities.Read moreRead less
Non-invasive prediction of adverse neural events using brain wave activity. This project aims to develop intelligent decision-making systems for non-invasive identification of adverse neural events (fatigue/freezing of gait) through real-time monitoring of brain wave activity. Analyses of the effectiveness of the changes in physiological parameters associated with electroencephalography (EEG) signals, advanced biomedical instrumentation, and optimal computational intelligence will form a basis f ....Non-invasive prediction of adverse neural events using brain wave activity. This project aims to develop intelligent decision-making systems for non-invasive identification of adverse neural events (fatigue/freezing of gait) through real-time monitoring of brain wave activity. Analyses of the effectiveness of the changes in physiological parameters associated with electroencephalography (EEG) signals, advanced biomedical instrumentation, and optimal computational intelligence will form a basis for the development of platform technology capable of monitoring and detection of neural health status. Success is expected to yield a new generation of smart dynamic non-invasive systems that will be critical for developing effective solutions to counter life threating conditions for a large cross section of the Australian population.Read moreRead less
Vision Model Based Perceptual Digital Video Coding. Digital video coding and compression is an enabling technology and has diversified applications in audiovisual communications, multimedia computing, digital television broadcast and electronic entertainment industries. The project aims at spearheading research in theory, techniques and implementation of perceptual video coding in order to achieve constant and guaranteed quality in visual communications and services. It will explore a new appr ....Vision Model Based Perceptual Digital Video Coding. Digital video coding and compression is an enabling technology and has diversified applications in audiovisual communications, multimedia computing, digital television broadcast and electronic entertainment industries. The project aims at spearheading research in theory, techniques and implementation of perceptual video coding in order to achieve constant and guaranteed quality in visual communications and services. It will explore a new approach to digital video coding other than the constant bit rate coding techniques which have dominated digital video research for the past four decades. It will form a part of the theoretical foundation and principles for the next generation video coding and compression techniques, and may lead to new standards and practice.Read moreRead less
Special Research Initiatives - Grant ID: SR0354500
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
- ....ARC Research Network in Microarray Technology. The primary aim of this proposal is to transform the premier genomic technology into a standard research tool; microarrays are now a priority for anyone studying the genetics underlying key biological processes. A principal challenge for the Australian research community is to capture all aspects of microarray technology and make them readily available. We will address these needs by developing a network to:
-establish regular research meetings,
-facilitate training in array methodologies and bioinformatics,
-co-ordinate innovation of technologies,-provide centralised data warehousing,
-provide access to automated high-level gene annotation,
-provide data mining tools,
-set standards for data management and exchangeRead moreRead less
Long-term Cloud Service Composition. This project proposes an economic model-based framework for the selection and composition of cloud services, thus creating an efficient market for cloud consumers and providers. The project will use economic models that incorporate a range of quality of service (QoS) parameters as a key driver for optimising the selection of cloud services and the acceptance of consumer requests. The main outcomes of this project aim to increase efficiencies in the cloud mark ....Long-term Cloud Service Composition. This project proposes an economic model-based framework for the selection and composition of cloud services, thus creating an efficient market for cloud consumers and providers. The project will use economic models that incorporate a range of quality of service (QoS) parameters as a key driver for optimising the selection of cloud services and the acceptance of consumer requests. The main outcomes of this project aim to increase efficiencies in the cloud market, benefiting consumers and providers.Read moreRead less
Regulation of Stress Hormone Receptors in the Brain. Our research will provide information on how the brain controls our response to stress and will allow the development of targeted strategies to reduce the possibility during chronic stress of the development of conditions such as anxiety and depression. This will improve mental health outcomes in Australia and add to Australia's economic and social stability.
Development of an Integrated Platform for Performance-Based Safety Assessment. Building fires are the cause of major fatalities and injuries amongst all types of accidental fires in Australia. With significant advancement in numerical simulation technique, computer models are becoming acceptable tools for fire safety designs. Nonetheless, these methods still suffer from large amount of manual inputs and lengthy computational times. This research project will address the prevalent deficiency in m ....Development of an Integrated Platform for Performance-Based Safety Assessment. Building fires are the cause of major fatalities and injuries amongst all types of accidental fires in Australia. With significant advancement in numerical simulation technique, computer models are becoming acceptable tools for fire safety designs. Nonetheless, these methods still suffer from large amount of manual inputs and lengthy computational times. This research project will address the prevalent deficiency in many of these computer models and develop a novel and innovative design methodology. The success of this project will revolutionize the computational tools for the industry realizing a convenient, robust and time-saving integrated platform catering for increasing future market demand.Read moreRead less
ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand add ....ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand addresses issues about methodology, modelling toolkits, and management and control. Practical applications are advanced via collaborative projects that address key issues in biology, environment, and socio-economics.Read moreRead less
The MYB gene as a model for global transcriptional regulation: stopping, starting and looping. This project will study how transcriptional elongation controls the MYB gene, a key regulator of normal and cancerous growth and regulation. There are three major benefits that are likely to flow from the proposed research It will strengthen research in new and important areas of transcriptional regulation, by building research capacity in Australia in the area of gene expression, particularly with res ....The MYB gene as a model for global transcriptional regulation: stopping, starting and looping. This project will study how transcriptional elongation controls the MYB gene, a key regulator of normal and cancerous growth and regulation. There are three major benefits that are likely to flow from the proposed research It will strengthen research in new and important areas of transcriptional regulation, by building research capacity in Australia in the area of gene expression, particularly with respect to transcriptional elongation and long-range regulation. It will highlight a new approach to the therapeutic targeting of MYB in cancer: data generated from this research may enable us to target MYB expression in a range of cancers including breast cancer by inhibiting transcriptional elongation. And it will provide training in advanced molecular biology to postdoctoral scientists and students.Read moreRead less