Cerebral Palsy (CP) is a devastating, common developmental brain disorder once assumed to be due to lack of oxygen at birth. Using our unique Biobank with DNA and clinical data from families with a CP child, we are examining the genetic origins of CP and how genes and risk factors in pregnancy contribute. We will use computer modelling and testing in animals and brain cells, to understand causes of CP and devise predictive, preventative and therapeutic strategies.
Vascular Contributions To Dementia: Prevention In Those At High-risk
Funder
National Health and Medical Research Council
Funding Amount
$718,105.00
Summary
10,000 older adults undergo surgeries on their heart every year. These adults are at high risk for dementia, as the factors that bring them to cardiovascular surgery are the same as those that associate with dementia: hypertension, type II diabetes, etc. This population is in fact not only at increased risk of dementia due to vascular ill-health, but also because of undergoing the surgery itself. This project aims to prevent dementia in this vulnerable group.