Perceiving Is Believing: Perceptual Inference Anomalies In Schizophrenia.
Funder
National Health and Medical Research Council
Funding Amount
$344,824.00
Summary
In this study we explore the brain-ability-behaviour relationships that can explain causes of the severe mental illness, schizophrenia. Changes in the brain in schizophrenia affect how people perceive the world around them. Perception relies on our ability to use information in memory to shape what we perceive. We will study brain activity and task abilities that help us to understand where why and how this process becomes disrupted in the brain in persons with schizophrenia.
Uncovering The Neural Mechanisms Of Obsessive-compulsive Disorder Using Brain Modelling
Funder
National Health and Medical Research Council
Funding Amount
$581,628.00
Summary
Obsessive-compulsive disorder (OCD) is an incurable mental illness and current therapies only mitigate its symptoms for a portion of individuals. Thus, there is a need to identify the neural causes of OCD to develop personalised therapies. We will combine mathematical modelling, computer simulations, and clinical and neuroimaging data to develop the first model of OCD. Outcomes from this study will enable targeted OCD research and the discovery of brain mechanisms supporting treatment response.
Cerebral Blood Flow During Psychogenic Non-epileptic Seizures.
Funder
National Health and Medical Research Council
Funding Amount
$397,322.00
Summary
We don't understand what happens during a non-epileptic seizure. Patients can't tell us and we can't use normal brain scanning during a seizure as the patient moves too much. Our idea is to take patients with non-epileptic seizures on the epilepsy wards who are being monitored and inject them with a radioactive tracer as soon as the seizure starts, then we can scan them afterwards to see what parts of their brain were active during the seizure, so we will understand what was happening.