Evaluation Of Circulating Endothelial Cells In Prostate Cancer Detection, Prognosis And Treatment Response
Funder
National Health and Medical Research Council
Funding Amount
$32,628.00
Summary
A current shortfall in clinical medicine is tests which discriminate different forms and severity of cancers. The project will aim to identify useful strategies based on blood factors of angiogenesis, a fundamental process in tumour growth and dissemination. Development of such tests may permit better delineation of prognosis, act as a surrogate marker of treatment efficacy and aid in developing and optimizing new treatments, key areas of need in prostate cancer.
Cytoskeletal Regulation Of Adhesion Structure And Cell Movement
Funder
National Health and Medical Research Council
Funding Amount
$60,420.00
Summary
Metastatic (secondary) cancers are a frequent cause of patient mortality. Central to the development of metastasis is cell motility-movement. A key component of cell movement is the way that cells bind and release the extra-cellular matrix as they move. By understanding how the dynamics of cell interaction with the matrix are regulated, we will identify molecules that are critical to the development of metastatic cancer and thus novel targets for inhibition of metastasis.