Optimizing the allocation of resources for defending marine protected areas against invasive species. The National Representative System of Marine Protected Areas contributes directly to the protection of marine biodiversity, and to Australia's international obligations under the UN Convention on Biological Diversity. Non-indigenous species have potential to undermine native biodiversity in marine protected areas across Australia. By identifying the most effective strategies for dealing with pot ....Optimizing the allocation of resources for defending marine protected areas against invasive species. The National Representative System of Marine Protected Areas contributes directly to the protection of marine biodiversity, and to Australia's international obligations under the UN Convention on Biological Diversity. Non-indigenous species have potential to undermine native biodiversity in marine protected areas across Australia. By identifying the most effective strategies for dealing with potential incursions of non-indigenous species in Victorian marine national parks and sanctuaries, the project will make a valuable contribution to the viability of local marine ecosystems and the maintenance of biodiversity. Furthermore, it will provide a template to aid similar decision-making in other marine protected areas around the country.Read moreRead less
Bioinks for the 3D printing of cells made from off-the-shelf components. This project aims to develop a simple method for creating complex, multiple-cell-type three-dimensional (3D) cell cultures for in-vitro cell based assays. Using 3D printing technology, this project will develop a versatile polymer system, made from entirely commercially available components, that gels upon printing and has functionality to assist cells in adhering, growing and migrating. The 3D printing of multiple cell typ ....Bioinks for the 3D printing of cells made from off-the-shelf components. This project aims to develop a simple method for creating complex, multiple-cell-type three-dimensional (3D) cell cultures for in-vitro cell based assays. Using 3D printing technology, this project will develop a versatile polymer system, made from entirely commercially available components, that gels upon printing and has functionality to assist cells in adhering, growing and migrating. The 3D printing of multiple cell types will provide biological scientists with more realistic in-vitro cell assays to those found in-vivo. Applications of the research are in cell biology, studying diseases and developing new drugs.Read moreRead less
Hazard identification, risk assessment and decision analysis for conservation and management of Australian marine parks. Victoria is the first jurisdiction in the world to proclaim an entire system of marine protected areas at once. The new management responsibilities have created imperatives for robust, scientifically defendable approaches to identifying threats, setting management priorities and developing monitoring systems. This project will develop, for the first time, a risk assessment pro ....Hazard identification, risk assessment and decision analysis for conservation and management of Australian marine parks. Victoria is the first jurisdiction in the world to proclaim an entire system of marine protected areas at once. The new management responsibilities have created imperatives for robust, scientifically defendable approaches to identifying threats, setting management priorities and developing monitoring systems. This project will develop, for the first time, a risk assessment protocol that has due regard for the perception of risks by individuals, and ensures that stakeholder values are an intrinsic part of decision-making. The protocol will create a system that stays faithful to the priorities of those who bear the risks, while using technical methods to ensure that models are consistent and that monitoring provides pertinent information.Read moreRead less
Advanced gravity and electromagnetic methods for uncovering the deep Earth. Advanced gravity and electromagnetic methods for uncovering the deep Earth. This project aims to improve the sensitivity of airborne gravity gradiometers and electromagnetic sensors so airborne surveys can detect underground structures at greater depths. Aircraft motion and turbulence limit the effectiveness of existing instruments. Advanced vibration isolation and noise reduction algorithms will allow instruments to ima ....Advanced gravity and electromagnetic methods for uncovering the deep Earth. Advanced gravity and electromagnetic methods for uncovering the deep Earth. This project aims to improve the sensitivity of airborne gravity gradiometers and electromagnetic sensors so airborne surveys can detect underground structures at greater depths. Aircraft motion and turbulence limit the effectiveness of existing instruments. Advanced vibration isolation and noise reduction algorithms will allow instruments to image to significantly greater depths, to map geology more accurately. This is expected to contribute to the discovery of new economic mineral and hydrocarbon resources.Read moreRead less
Radio-magnetic nanoparticles as bimodal positron emission tomography/magnetic resonance imaging contrast agents for dendritic cell tracking. Biomedical imaging is limited by a lack of commercial dual-mode contrast agents, which may be simultaneously used for magnetic resonance (MR) and positron emission tomography (PET) imaging. This project will develop a nanotechnology-based biocompatible dual-mode contrast agent for simultaneous PET and MR imaging, reducing associated side effects.
Mass-production of beneficial insects for commercial pest management - physicochemical definition of oviposition sites for development of cost-efficient artificial substrates. The mass-production of beneficial insects for commercial purposes demands the development of cost-effective techniques for breeding and distributing them to growers. Many predatory beneficial insects lay their eggs in sites that prevent effective mass culturing. To circumvent this difficulty, it should be possible to defin ....Mass-production of beneficial insects for commercial pest management - physicochemical definition of oviposition sites for development of cost-efficient artificial substrates. The mass-production of beneficial insects for commercial purposes demands the development of cost-effective techniques for breeding and distributing them to growers. Many predatory beneficial insects lay their eggs in sites that prevent effective mass culturing. To circumvent this difficulty, it should be possible to define such oviposition sites in chemical and physical terms, and then use the information to develop artificial substrates that are convenient for mass rearing the insects and for disseminating them to growers. We will use the mealybug predator Cryptolaemus montrouszieri to test the feasibility of this approach and to assess its application to other beneficial species.Read moreRead less
Establishment of Therapeutically Relevant Animal Models and Markers for Crohn's Disease. Crohn's disease is a devastating life long disease, affecting 0.5% of the world population. There is urgent economic and social need to develop new and better drugs to treat the symptoms and underlying cause of this debilitating disease. Social benefits include the improved quality of life of sufferers that positively impacts society. Economic benefit includes income derived from commercialisation of rese ....Establishment of Therapeutically Relevant Animal Models and Markers for Crohn's Disease. Crohn's disease is a devastating life long disease, affecting 0.5% of the world population. There is urgent economic and social need to develop new and better drugs to treat the symptoms and underlying cause of this debilitating disease. Social benefits include the improved quality of life of sufferers that positively impacts society. Economic benefit includes income derived from commercialisation of research outcomes and the contribution this project makes to high value employment in the biotechnology sector.Read moreRead less
High performance electromagnetic airborne mineral exploration for discovery of deep earth resources. Airborne mineral exploration underpins Australia’s mining industry. Sensing systems are particularly effective for discovering nickel ore and water bodies but salty soil often blocks signals. This project uses a patented breakthrough in vibration isolation to create instruments able to detect minerals 50 per cent to 100 per cent deeper than normal.
Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel de ....Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel device, comprising advanced microfluidics and biosensing technology for parasite quantification, genotyping and viability analysis. Expected outcomes are improved Cryptosporidium management, risk prediction, and rapid mitigation of impending outbreaks. The proposed platform has a great potential for detecting other pathogens.Read moreRead less
Improving the operation of large-scale irrigation networks through automation. Channel networks for irrigation are critical infrastructure. Efficient operation is important in terms of sustainability and food security. This project aims to deliver automatic control techniques for improving system-wide performance. The research outcomes will secure Australia's place at the forefront of irrigation network automation technology.