Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Neuromorphic Sensing and Diagnostics with Carbon: Towards a Biomimetic Nose. Neuromorphic electronics emulates cognitive processes of the brain and like the brain, is capable of extracting features and recognising patterns within data with extremely low energy requirements. Carbon materials are naturally adapted to neuromorphic electronics and uniquely form a compatible interface for sensing molecules in liquid and gaseous media. This project aims to develop a carbon-based neuromorphic electroni ....Neuromorphic Sensing and Diagnostics with Carbon: Towards a Biomimetic Nose. Neuromorphic electronics emulates cognitive processes of the brain and like the brain, is capable of extracting features and recognising patterns within data with extremely low energy requirements. Carbon materials are naturally adapted to neuromorphic electronics and uniquely form a compatible interface for sensing molecules in liquid and gaseous media. This project aims to develop a carbon-based neuromorphic electronic sensing device and couple it with carbon based neuromorphic pattern recognition technology to build an ‘artificial nose’ for improved health and environmental monitoring. Intended outcomes will include a technology for low-cost and rapid diagnostic services.
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Surface tension-confined microfluidics: moving towards a flexible platform for diagnostics. The point-of-care industry is poised to fulfil the international need for effective and mobile diagnostics tools; however current strategies are restricting this from becoming a reality. Surface tension-confined microfluidics provide an opportunity to meet the requirements necessary for flexible platform for point-of-care devices.
Discovery Early Career Researcher Award - Grant ID: DE140101056
Funder
Australian Research Council
Funding Amount
$380,156.00
Summary
Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-partic ....Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-particle level and the choice of optimal SERS-active three-dimensional superstructures for use will be guided by empirical structure-activity correlations in combination with computer simulations. Tumour biomarkers for breast cancer will be employed as the model target for establishing the detection platform in a portable configuration for point-of-care diagnostics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100115
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploi ....High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploit interfacial phenomena and to tailor processing-microstructure-composition correlations, so as to design new materials with the best performance possible. Probes with unique capabilities will measure surface morphology, optical properties, elemental composition and crystallographic phase.The facility will be the first in Australia to offer a comprehensive study of structure and properties at high temperature.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100569
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Ultra-Porous Devices by Synergistic Aerosol and Atomic Layer Depositions. The project aspires to develop a scalable low-cost approach for the synthesis and integration of ultra-porous films in nanodevices. The project intends to deposit atomic layers onto aerogel-like nanoparticle networks, self-assembled by thermophoresis of flame-made aerosols. This would increase the atomically-deposited layer mass by several hundred-fold per cycle and result in ultra-porous films with electrochemically activ ....Ultra-Porous Devices by Synergistic Aerosol and Atomic Layer Depositions. The project aspires to develop a scalable low-cost approach for the synthesis and integration of ultra-porous films in nanodevices. The project intends to deposit atomic layers onto aerogel-like nanoparticle networks, self-assembled by thermophoresis of flame-made aerosols. This would increase the atomically-deposited layer mass by several hundred-fold per cycle and result in ultra-porous films with electrochemically active surface areas. It is intended that the project will demonstrate the fabrication of solid–gas, solid–liquid and solid–solid nanointerfaces, which will be applicable to key emerging technologies such as wearable medical diagnostics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100112
Funder
Australian Research Council
Funding Amount
$275,000.00
Summary
A Raman facility for advanced research supporting Australia’s natural gas, oil, coal and minerals industries. This modern Raman Spectroscopy facility will support the science and engineering that underpins the production and processing of Australia’s natural resources. Using high-pressure fibre optics, novel lasers and advanced imaging, the facility will enable the monitoring and improvement of processes and materials under extreme conditions.
Two-dimensional plasmonic heterogeneous nanostructures for photocatalysis. This project aims to design and explore two-dimensional heterogeneous photocatalysts that can convert solar energy into usable chemical energy. This project will investigate the correlation between surface plasmonic resonance and photocatalytic activities on the atomic level. Heterogeneous engineering and in-situ investigation of atomic-level photocatalytic dynamics is expected to yield several new full-solar-spectrum pho ....Two-dimensional plasmonic heterogeneous nanostructures for photocatalysis. This project aims to design and explore two-dimensional heterogeneous photocatalysts that can convert solar energy into usable chemical energy. This project will investigate the correlation between surface plasmonic resonance and photocatalytic activities on the atomic level. Heterogeneous engineering and in-situ investigation of atomic-level photocatalytic dynamics is expected to yield several new full-solar-spectrum photocatalysts. The project is expected to contribute to the understanding of the processes and mechanisms underlying photocatalysis, and lead to useable, stable and durable photocatalytics. The outcomes will enable efficient, cost-effective and reliable production of clean energy in a low-emission way.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL170100014
Funder
Australian Research Council
Funding Amount
$3,275,680.00
Summary
Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromo ....Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromolecules to advanced functional photoresists for 3D laser lithography as well as materials that self-report structural transformations by light or are reprogrammable in their properties by photonic fields. Harnessing the power of light as a precision tool for the construction of advanced macromolecular materials will provide technology outcomes for Australian manufacturing industries from electronics to health. This includes laser-driven 3D printing technology at the nano-level, light-adaptive smart reprogrammable coatings and materials, synthetic proteins responsive to light as well as tailor-made single cell niches.Read moreRead less