The Role Of Capsid Protein Nucleolar Localisation In Chikungunya Virus: Implications For Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$520,520.00
Summary
Chikungunya virus (CHIKV) is a globally widespread mosquito-borne alphavirus capable of causing considerable human morbidity and mortality. With no CHIKV vaccine or antiviral available this proposal aims to develop a live attenuated CHIKV vaccine, rationally designed by investigating the host cell nucleolar trafficking of CHIKV capsid protein. This vaccine has the potential to provide cross-protection against additional arthritogenic alphaviruses endemic to Australia such as Ross River virus.
Industrial Transformation Training Centres - Grant ID: IC230100036
Funder
Australian Research Council
Funding Amount
$4,999,600.00
Summary
ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical ....ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical production, more resilient spacecraft and robust regulatory frameworks. Industries and communities will benefit from a future workforce prepared for safe adoption, development and delivery of emerging techniques and advanced radiation technologies, enhancing Australia’s prosperity and security.Read moreRead less
ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies ....ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies (CAMS) will bring together key Australian and international scientists to work in this emerging scientific field of antimatter-matter interactions. It will forge a unique and effective scientific team for state-of-the-art studies of the nano-world that underlies many everyday processes and new technologies.Read moreRead less
Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si a ....Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si alleviates stress in wheat, from gene to farm scale, providing cost-benefit analysis and a best–practice toolbox for implementation by farmers. Outcomes are anticipated to provide a cheaper and more environmentally sustainable solution to issues of water scarcity and yield losses to pests in Australia’s leading crop.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100030
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub in Intelligent Robotic Systems for Real-Time Asset Management. This hub aims to transform the way assets and infrastructure are managed by developing new capabilities for intelligent robotic systems for inspection, monitoring, and maintenance. The hub expects to generate new knowledge in robotics and associated fields including sensing, planning, data processing, and machine learning using interdisciplinary approaches and tight collaboration between academia and industry. The ex ....ARC Research Hub in Intelligent Robotic Systems for Real-Time Asset Management. This hub aims to transform the way assets and infrastructure are managed by developing new capabilities for intelligent robotic systems for inspection, monitoring, and maintenance. The hub expects to generate new knowledge in robotics and associated fields including sensing, planning, data processing, and machine learning using interdisciplinary approaches and tight collaboration between academia and industry. The expected outcomes are robots with the ability to autonomously collect data for integration into a digital twin that provides a real-time representation of the true state of a physical asset. The benefits include both improved asset management and establishing Australia as a leading manufacturer of advanced robotic systems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100155
Funder
Australian Research Council
Funding Amount
$370,000.00
Summary
An Ultra-wideband Radio Receiver for the Parkes 64-metre Radio Telescope. An ultra-wideband radio receiver for the Parkes 64-metre radio telescope: This project aims to construct a state-of-the-art ultra-wide-band receiver and signal processing system for the Parkes 64-metre radio telescope. The receiver will operate across the entire 700 megahertz to four gigahertz band with outstanding sensitivity and polarimetric performance, providing a unique capability for high-time-resolution wide-bandwid ....An Ultra-wideband Radio Receiver for the Parkes 64-metre Radio Telescope. An ultra-wideband radio receiver for the Parkes 64-metre radio telescope: This project aims to construct a state-of-the-art ultra-wide-band receiver and signal processing system for the Parkes 64-metre radio telescope. The receiver will operate across the entire 700 megahertz to four gigahertz band with outstanding sensitivity and polarimetric performance, providing a unique capability for high-time-resolution wide-bandwidth astronomy. It is expected to deliver enhanced science outcomes for a wide range of projects and greatly improve the telescope's operational efficiency, extending its lifetime into the Square Kilometre Array era. Key science projects include tests of theories of relativistic gravitation, including the search for gravitational waves, probing neutron star interiors and investigations of the magnetic structure of our galaxy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100107
Funder
Australian Research Council
Funding Amount
$672,000.00
Summary
The next generation fast radio burst detector for Australia. This project intends to provide a next-generation fast radio burst detector for the Australian Square Kilometre Array Pathfinder. The project expects to both transform our understanding of fast radio bursts, enigmatic flashes of radio waves of unknown origin, but also use the bursts as tools to study the cosmic web of matter that resides in intergalactic space. To do so, the project aims to deliver a more sensitive detection system ca ....The next generation fast radio burst detector for Australia. This project intends to provide a next-generation fast radio burst detector for the Australian Square Kilometre Array Pathfinder. The project expects to both transform our understanding of fast radio bursts, enigmatic flashes of radio waves of unknown origin, but also use the bursts as tools to study the cosmic web of matter that resides in intergalactic space. To do so, the project aims to deliver a more sensitive detection system capable of localising a large sample of fast radio bursts to greater distances, found commensal to other observations. This should provide significant benefit, including the resolutions to key open astrophysical questions and improved scientific outcomes for transient searches with the Square Kilometre Array.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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