Automated 3-Dimensional Biomedical Registration for Whole-body Images from Combined PET/CT Scanners. This project will aid rapid assimilation of very large medical imaging datasets from different imaging devices, and will have clinical applications in diagnosis and treatment and improve patient care. The research, when extended to protein registration, will facilitate analysis of DNA and advance research in bioinformatics and biotechnology. The research could also be used for target recognition, ....Automated 3-Dimensional Biomedical Registration for Whole-body Images from Combined PET/CT Scanners. This project will aid rapid assimilation of very large medical imaging datasets from different imaging devices, and will have clinical applications in diagnosis and treatment and improve patient care. The research, when extended to protein registration, will facilitate analysis of DNA and advance research in bioinformatics and biotechnology. The research could also be used for target recognition, mosaic construction, content-based retrieval, in remote sensing and multimedia. Benefits to Australia include the provision of a readily adaptable image registration program for patient care (e.g., early detection of cancers, dementia), cutting-edge research, high-quality training for students, and encouraging international research collaboration.Read moreRead less
Correction of the Effects of Gradient Field Nonlinearity in Magnetic Resonance Imaging - A Complete 3-Dimensional Approach. The outcomes of this research will have direct benefits to various areas of diagnostic and interventional medicine especially in neurological diseases such as Alzheimer's disease, stroke, multiple sclerosis or brain tumors. The techniques developed in this project will in general enable MRI to provide a higher quality service to the community.
Rare isotopes as tracers of prosthesis debris. The incidence of knee replacement surgery in Australia is 30,000 per year. Limited by wear debris, the lifespan of knee implants is only 10-15 years and can be much shorter. Due to increasing life expectancy, many patients need several surgical procedures. As a multi-disciplinary team of materials-, isotope-tracing- and medical-experts, we aim to understand and monitor wear debris in prostheses. Knee replacement surgery alone imposes a high burden o ....Rare isotopes as tracers of prosthesis debris. The incidence of knee replacement surgery in Australia is 30,000 per year. Limited by wear debris, the lifespan of knee implants is only 10-15 years and can be much shorter. Due to increasing life expectancy, many patients need several surgical procedures. As a multi-disciplinary team of materials-, isotope-tracing- and medical-experts, we aim to understand and monitor wear debris in prostheses. Knee replacement surgery alone imposes a high burden of annually half a billion dollars on the Australian health budget. Controlling and reducing wear debris in prosthesis joints would reduce these costs and improve patients' quality of life.Read moreRead less
New methods to improve regional isotope therapy of liver tumours in cancer patients. The most common cause of death in cancer patients is secondary tumours in vital organs. Successful treatment of liver tumours with regional isotope therapy now offers improved survival rates. This project will research novel radiolabelled nanoparticles and advanced computer imaging algorithms to improve regional isotope therapy of liver tumours. It will provide better methods of objective assessment and manageme ....New methods to improve regional isotope therapy of liver tumours in cancer patients. The most common cause of death in cancer patients is secondary tumours in vital organs. Successful treatment of liver tumours with regional isotope therapy now offers improved survival rates. This project will research novel radiolabelled nanoparticles and advanced computer imaging algorithms to improve regional isotope therapy of liver tumours. It will provide better methods of objective assessment and management that can reduce risk and improve patient survival.Read moreRead less
Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinicia ....Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinician to reduce fetal deaths and enhance the chances of good outcomes with resultant savings in social and financial costs to the community. The development of such equipment would spawn future research into intervention treatments and contribute to Australia's position as a world leader in computerised health monitoring systems.Read moreRead less
Multi-Channel Time-Frequency Analysis for EEG Neonatal Seizure Characterization. This project researches new signal processing methodologies for a multi-channel characterization of seizures for use in diagnosing newborn brain dysfunctions. The outcomes will result in important immediate clinical benefits for sick newborn babies and will fundamentally facilitate research progress in the development of neuroprotectants and anticonvulsants. The success of this project will contribute in minimizing ....Multi-Channel Time-Frequency Analysis for EEG Neonatal Seizure Characterization. This project researches new signal processing methodologies for a multi-channel characterization of seizures for use in diagnosing newborn brain dysfunctions. The outcomes will result in important immediate clinical benefits for sick newborn babies and will fundamentally facilitate research progress in the development of neuroprotectants and anticonvulsants. The success of this project will contribute in minimizing the social financial costs by diagnosing brain disorders in the initial stage of life and preventing further damage. This has the potential to result in a standard diagnostic equipment in neonatal intensive care units and medical research centres.Read moreRead less
Design of Neonatal Seizure Diagnosis Methods Using Time-Frequency Signal Processing Techniques. Seizures occur in approximately 0.5% of all newborns. They are often the only indicator of an early dysfunction in central nervous system (CNS). Their occurrence raises concerns about the underlying cause, its effect on the brain, and the appropriate treatment. Newborn seizures are mostly sub-clinical and only detected through the Electroencephalogram. For an efficient diagnosis, seizure classificatio ....Design of Neonatal Seizure Diagnosis Methods Using Time-Frequency Signal Processing Techniques. Seizures occur in approximately 0.5% of all newborns. They are often the only indicator of an early dysfunction in central nervous system (CNS). Their occurrence raises concerns about the underlying cause, its effect on the brain, and the appropriate treatment. Newborn seizures are mostly sub-clinical and only detected through the Electroencephalogram. For an efficient diagnosis, seizure classification systems were proposed based on visual observations. This project proposes developing a novel approach to automate the classification process using time-frequency (TF) signal processing techniques based on the multi-channel characteristics of the seizure; namely: A) TF signature B) origin, and C) propagation behaviour.Read moreRead less
ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this te ....ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this team with the foremost international authorities and leading industry players in the area of sensor networks. This research network will guide collaborative research that will ensure Australia to play a world leading role in sensor network development and implementation.
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Special Research Initiatives - Grant ID: SR0354767
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Intelligent Sensors, Sensor Networks and Information Processing. Recent emergence of very large number of diverse sensors and sensor networks has the potential to impact on the quality of all areas of life. Scientific challenges in realizing this potential is significant because of the multidisciplinary nature and complexities involved. This research network builds on the best scientific talent available in the interdisciplinary areas (biology, mathematics, statistics, computing, electrical en ....Intelligent Sensors, Sensor Networks and Information Processing. Recent emergence of very large number of diverse sensors and sensor networks has the potential to impact on the quality of all areas of life. Scientific challenges in realizing this potential is significant because of the multidisciplinary nature and complexities involved. This research network builds on the best scientific talent available in the interdisciplinary areas (biology, mathematics, statistics, computing, electrical engineering and mechanical engineering) with the best overseas scientific teams to solve the underlying scientific problems to enable the Australian industry to exploit and apply this technology in areas of defense, health care and environment.Read moreRead less
Towards early detection of upper airway obstruction in children: investigation of autonomic control. This project focuses on the investigation of new indicators for early detection of upper airway obstruction (UAO)-which is a common sleep disorder in children. Failure to treat UAO can result in serious adverse outcomes including failure to thrive, neurocognitive deficits, developmental delay, behavioural disorders and cardiovascular disease. Thus, early treatment of UAO will significantly improv ....Towards early detection of upper airway obstruction in children: investigation of autonomic control. This project focuses on the investigation of new indicators for early detection of upper airway obstruction (UAO)-which is a common sleep disorder in children. Failure to treat UAO can result in serious adverse outcomes including failure to thrive, neurocognitive deficits, developmental delay, behavioural disorders and cardiovascular disease. Thus, early treatment of UAO will significantly improve quality of life for the child. Direct benefits to community health via reduced costs for medical treatment will also be a key outcome. The establishment of new diagnostic indicators will form the basis of new tools for identifying child sleep disorders and contribute to advancing Australia's international leading position in health technology. Read moreRead less