Industrial Transformation Training Centres - Grant ID: IC230100036
Funder
Australian Research Council
Funding Amount
$4,999,600.00
Summary
ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical ....ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical production, more resilient spacecraft and robust regulatory frameworks. Industries and communities will benefit from a future workforce prepared for safe adoption, development and delivery of emerging techniques and advanced radiation technologies, enhancing Australia’s prosperity and security.Read moreRead less
Positron Nano-Dosimetry: Fundamental Measurements of Positron Interactions and their use in State-of-the-Art Modelling of Positron Transport. This proposal will provide unique experimental and theoretical information on how positrons, the electron antiparticles, interact with matter, in particular with biologically important molecules. This data will be used in a unique set of modelling approaches which will provide, for the first time, an insight into how positrons are transported through gases ....Positron Nano-Dosimetry: Fundamental Measurements of Positron Interactions and their use in State-of-the-Art Modelling of Positron Transport. This proposal will provide unique experimental and theoretical information on how positrons, the electron antiparticles, interact with matter, in particular with biologically important molecules. This data will be used in a unique set of modelling approaches which will provide, for the first time, an insight into how positrons are transported through gases, liquids and ultimately, soft matter. It will thus have important ramifications for diagnostic tools such as Positron Emission Tomography. The fundamental research will also shed light on one of the key 'mysteries' of life - why the biological building blocks of life possess a definite " handedness", or chirality.Read moreRead less
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Unravelling the molecular diversity and evolution of centipede venoms. The project intends to improve understanding of venom evolution in centipedes. Venoms have emerged as a rich source of pharmacological tools with potential for development into therapeutics and bioinsecticides. However, venoms-based discovery has been limited by the narrow taxonomical range of animals studied, with many groups of venomous animals overlooked. One such group is centipedes, whose venoms contain diverse toxins th ....Unravelling the molecular diversity and evolution of centipede venoms. The project intends to improve understanding of venom evolution in centipedes. Venoms have emerged as a rich source of pharmacological tools with potential for development into therapeutics and bioinsecticides. However, venoms-based discovery has been limited by the narrow taxonomical range of animals studied, with many groups of venomous animals overlooked. One such group is centipedes, whose venoms contain diverse toxins that differ between taxa. This project aims to provide an insight into centipede venom evolution, and how it might be constrained by venom-gland morphology. This study seeks to contribute to our understanding of protein evolution and direct biodiscovery efforts around centipede venom.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882531
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Quantum Limited Single Atom Detectors. The technology that has shaped our society, solid state diodes, transistors and computer chips is based on our ability to manipulate the average quantum properties of materials such as semiconductors. This physics has been well understood for decades. Many technologies that will shape our societies in this century will be based on our ability to manipulate quantum systems precisely, an area that is the focus of quantum atom optics. The detectors requested i ....Quantum Limited Single Atom Detectors. The technology that has shaped our society, solid state diodes, transistors and computer chips is based on our ability to manipulate the average quantum properties of materials such as semiconductors. This physics has been well understood for decades. Many technologies that will shape our societies in this century will be based on our ability to manipulate quantum systems precisely, an area that is the focus of quantum atom optics. The detectors requested in this proposal will ensure that Australia remains competitive in the technologies that will emerge from the new field of quantum atom optics.Read moreRead less
Gain from pain: new tools from venomous animals for exploring pain pathways. This project aims to explore animal venoms for new pain-causing toxins, to determine their structure and mechanism of action. Many venomous animals use their venom defensively and envenomation is frequently associated with rapid and often excruciating pain. In most cases the molecular mechanisms by which they achieve this is unknown. Using biochemical, pharmacological and biophysical techniques, this project expects to ....Gain from pain: new tools from venomous animals for exploring pain pathways. This project aims to explore animal venoms for new pain-causing toxins, to determine their structure and mechanism of action. Many venomous animals use their venom defensively and envenomation is frequently associated with rapid and often excruciating pain. In most cases the molecular mechanisms by which they achieve this is unknown. Using biochemical, pharmacological and biophysical techniques, this project expects to uncover toxins that employ new mechanisms of pain signalling, leading to new insights into pain physiology.Read moreRead less
Time-space resolved photoelectron emission to control molecular processes. This project aims to resolve simultaneously the timing and space localisation of photoelectron emission from atoms and molecules as a means for targeted breaking of molecular bonds. Existing techniques determine the timing and spatial characteristics of photoemission independently. The simultaneous time-space resolution will allow for the precise manipulation of photoelectrons by a sequence of phase-stabilised laser pulse ....Time-space resolved photoelectron emission to control molecular processes. This project aims to resolve simultaneously the timing and space localisation of photoelectron emission from atoms and molecules as a means for targeted breaking of molecular bonds. Existing techniques determine the timing and spatial characteristics of photoemission independently. The simultaneous time-space resolution will allow for the precise manipulation of photoelectrons by a sequence of phase-stabilised laser pulses, a technique known as coherent control. The benefit of this project will be the coherently controlled breaking of molecular bonds in oxide, carbonyl and hydrocarbon molecules. The outcome will be a significant step forward in driving complex photochemical reactions in industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453256
Funder
Australian Research Council
Funding Amount
$512,573.00
Summary
National Positron Beamline Facility. We shall construct an experimental facility for the study of positron interactions with atoms, molecules and condensed matter. It will
- Provide a unique Australian facility for the study of positron interactions with matter
- Provide benchmark data for low energy positron interactions with atoms and molecules and a reference point for theoretical calculations
- Provide Australian materials scientists with a new tool for the development of novel material ....National Positron Beamline Facility. We shall construct an experimental facility for the study of positron interactions with atoms, molecules and condensed matter. It will
- Provide a unique Australian facility for the study of positron interactions with matter
- Provide benchmark data for low energy positron interactions with atoms and molecules and a reference point for theoretical calculations
- Provide Australian materials scientists with a new tool for the development of novel materials and thin film technology
- Provide new insight on the mechanisms of positron binding to matter
- Address a National Research Priority: Frontier Technologies for Building and Transforming Australian Industries.
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Australian Centre for Quantum-Atom Optics. The Centre will combine pre-eminent Australian theoretical and experimental research groups in quantum and atom optics to create a powerful network to advance the rapidly developing field of Quantum-Atom Optics. We will exploit the quantum nature of multiple particle quantum states of atoms and photons including entangled light and Bose-Einstein condensates. The Centre will focus on fundamental research, but our long term goal is to underpin and develo ....Australian Centre for Quantum-Atom Optics. The Centre will combine pre-eminent Australian theoretical and experimental research groups in quantum and atom optics to create a powerful network to advance the rapidly developing field of Quantum-Atom Optics. We will exploit the quantum nature of multiple particle quantum states of atoms and photons including entangled light and Bose-Einstein condensates. The Centre will focus on fundamental research, but our long term goal is to underpin and develop the next generation quantum technology. We aim to build a quantum toolbox to enable applications such as the transfer and storage of information for photonics, and precision quantum control of atoms for enhanced atom interferometry.Read moreRead less