Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international effo ....Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international efforts in this area, via the development of statistical methods for segmenting genomes, classification of those segments, and study of the resulting classes. In the long term, enhanced understanding of eukaryotic cells will lead to breakthroughs in biology, and to medical, pharmaceutical, agricultural and scientific advances.Read moreRead less
Dynamics and correlations of many-body systems. The proposed program will greatly enhance Australian science through linking innovative
theoretical techniques with the successful ongoing Australian experimental program in atom
lasers, atom chip interferometry and ultra-cold fermions. Pioneering theoretical methods in
quantum phase-space are internationally recognized, and will be extended into new areas relevant
to Australia. These have fundamental significance to fields ranging from nanotec ....Dynamics and correlations of many-body systems. The proposed program will greatly enhance Australian science through linking innovative
theoretical techniques with the successful ongoing Australian experimental program in atom
lasers, atom chip interferometry and ultra-cold fermions. Pioneering theoretical methods in
quantum phase-space are internationally recognized, and will be extended into new areas relevant
to Australia. These have fundamental significance to fields ranging from nanotechnology to
astrophysics, as well as providing a route to improved atomic clocks and other instruments.
Combining these theoretical and computational methods from the physical sciences with biology
and genetics will provide future cross-disciplinary benefits to Australian biomedical science.Read moreRead less
New Approaches to the Analysis of Count Time Series. The focus of this proposal is on the analysis of data that enumerate events over time. Occurrences of such count data abound in economics and business, examples being observations on insurance claims, loan defaults and individual product demand. This project develops a suite of innovative methods for modelling and predicting event counts. The methods explicitly accommodate both the discreteness of the data and possible complexities in its evo ....New Approaches to the Analysis of Count Time Series. The focus of this proposal is on the analysis of data that enumerate events over time. Occurrences of such count data abound in economics and business, examples being observations on insurance claims, loan defaults and individual product demand. This project develops a suite of innovative methods for modelling and predicting event counts. The methods explicitly accommodate both the discreteness of the data and possible complexities in its evolution over time. In so doing, they enable both accurate inferences regarding the dynamic structure of the data to be drawn and accurate forecasts of future event counts to be produced.Read moreRead less