Improving Birth Outcomes in China: consequences and potentials of policy, state and professional interactions. The aim of the project is to reduce morbidity and mortality associated with birth by informing health systems improvement in China. We will develop an innovative methodology to study consequences of policy, state and professional interactions on birth outcomes. This work is also relevant in other settings. Macro economic reforms in China have produced paradoxical disparities between ri ....Improving Birth Outcomes in China: consequences and potentials of policy, state and professional interactions. The aim of the project is to reduce morbidity and mortality associated with birth by informing health systems improvement in China. We will develop an innovative methodology to study consequences of policy, state and professional interactions on birth outcomes. This work is also relevant in other settings. Macro economic reforms in China have produced paradoxical disparities between rich and poor and urban and rural populations evident in maternal morbidity and mortality. Results will inform facilitative policies and models of service to optimise safety and increase effectiveness in deployment of human and monetary resources.Read moreRead less
A Randomised Placebo-controlled Trial Of Antibiotics To Prevent Urinary Tract Infection In Children
Funder
National Health and Medical Research Council
Funding Amount
$735,000.00
Summary
This study is needed to determine whether a common clinical practice long-term antibiotic treatment for children following urinary tract infection (UTI) - is safe and effective in preventing further UTI and if so, whether all appropriate children are being treated. UTI will affect about 10% of Australian children by high school age (88,000 children per year). Because UTI may damage the kidneys, the management priority for children with UTI has been prevention of further infection. Currently this ....This study is needed to determine whether a common clinical practice long-term antibiotic treatment for children following urinary tract infection (UTI) - is safe and effective in preventing further UTI and if so, whether all appropriate children are being treated. UTI will affect about 10% of Australian children by high school age (88,000 children per year). Because UTI may damage the kidneys, the management priority for children with UTI has been prevention of further infection. Currently this means the identification of children thought to be most at risk of recurrent UTI by renal tract imaging. Those found to have reflux of urine from the bladder to the kidney (present in about 30% of those with UTI) are then placed on antibiotics fro 2-5 years. Unfortunately there has never been a properly designed trial to test whether antibiotics do really prevent UTI and if so, whether children with reflux are the appropriate and only group requiring treatment. Long term antibiotics may in fact do more harm than good because of side effects like skin, bowel and blood problems and because resistant bacteria may develop. The design of this study involves the random allocation of placebo or antibiotic (cotrimoxazole, the usual antibiotic given in this case) to about 800 children after their first symptomatic UTI. These children are treated and followed for one year to determine the rate of futher UTI in both groups. Any difference in outcome between the two groups of children will be because of the antibiotic treatment. This study may prove long-term antibiotics are ineffective and therefore should not be routinely used. In this case investigation of children to detect vesicoureteric reflux would serve little purpose and should be abandoned. Alternatively antibiotic treatment may be shown as effective treatment for preventing further UTI and in this case the study will clearly identify those children who will benefit.Read moreRead less
Achieving true representation of Indigenous people in nursing and midwifery. This project aims to address an absence of true representation of Aboriginal and Torres Strait Islander peoples and knowledges in nursing and midwifery. Significantly it intends to co-create an Aboriginal and Torres Strait Islander nurse and midwife theory and principles for practice. An anticipated goal of the research is to better understand how the theory and practice can be implemented in nurse and midwifery educati ....Achieving true representation of Indigenous people in nursing and midwifery. This project aims to address an absence of true representation of Aboriginal and Torres Strait Islander peoples and knowledges in nursing and midwifery. Significantly it intends to co-create an Aboriginal and Torres Strait Islander nurse and midwife theory and principles for practice. An anticipated goal of the research is to better understand how the theory and practice can be implemented in nurse and midwifery education (inclusive of clinical settings) in regional and urban areas. The intended outcome is to provide improved cultural safety in nursing and midwifery, greater cultural safety for health consumers and; stronger recruitment and retention of Indigenous nurses and midwives.
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