The Role Of Bisphenol A In The Development Of Chronic Disease
Funder
National Health and Medical Research Council
Funding Amount
$397,549.00
Summary
There is accumulating evidence to suggest that the environment we live in may be important in the development of chronic disease. This project examines a key environmental toxin Bisphenol A (BPA) and explores the role it has in the development of diabetes, obesity and cardiovascular disease (CVD). In this project, we will explore whether there is an independent relationship between BPA and the development of diabetes, CVD and obesity in humans in a prospective setting.
Although the major risk factors for cardiovascular diseases have been known for decades, and modern-day treatment is much advanced, the importance of these diseases persists, such that they remain the number one killer in Australia. This suggests that more can be done to correctly identify those at high and moderate risk of future disease, so as to optimize advice and medical treatment. This project will use the best evidence available to develop new methods of risk prediction and prevention.
Metabolically Healthy Obesity: An Investigation Of Its Predictors And Outcomes Across The Lifecourse
Funder
National Health and Medical Research Council
Funding Amount
$337,031.00
Summary
Obesity is a major health problem with 30% of Australian adults being obese. Despite attention on the health impact of obesity and programs to reduce weight, maintaining weight loss is difficult. However, not all obese individuals are at higher risk of disease. This research will examine the behavioural and genetic factors of these individuals and their risk of disease. The findings may inform new treatments for obesity that focus less on weight loss and more on health.
Building Urban Planning And Health Evidence To Inform Policy And Practice That Creates Healthy, Liveable And Equitable Communities Designed To Prevent Non-communicable Diseases
Funder
National Health and Medical Research Council
Funding Amount
$851,980.00
Summary
City planning directly and indirectly affects the health of residents. For example, ‘affordable’ housing on the urban fringe typically has poor access to public transport, shops and services. This increases motor vehicle dependency and time spent driving which increases levels of physical inactivity, sedentariness, obesity, social isolation and air pollution. This research focuses on how to build communities that promote health and wellbeing in residents.
Dietary Patterns, Cognitive Performance And Cardiovascular Risk Factors In Australia, The United States And Luxembourg: An International Comparison And Dietary Intervention Trial
Funder
National Health and Medical Research Council
Funding Amount
$347,227.00
Summary
Ageing and the growing obesity epidemic are two contributing factors to cognitive decline. This research will identify dietary patterns that are associated with better cognitive function using data from individuals in Australia, the United States and Europe, and be used to guide dietary strategies to prevent or slow cognitive decline in at-risk individuals. Delaying or preventing the onset of dementia will save the Australian health care system billions of dollars.
Lifecourse Investigation Of Obesity And Adverse Cardiometabolic Health Outcomes: A Pooled Analysis Of Cohort Studies
Funder
National Health and Medical Research Council
Funding Amount
$393,278.00
Summary
Obesity cost Australia over $58 billion in 2008 alone. We are yet to identify any effective preventive strategies. Limited existing data suggests childhood factors (e.g., obesity) may have a long-term impact on health outcomes. The proposed study will examine the link between childhood factors and cardiovascular disease risk in adulthood in 4 studies that have collected biological and lifestyle factors from childhood to adulthood. This will lead to better understanding of such complex diseases.
Implications Of The Increasing Duration Of Life Spent With Obesity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$251,830.00
Summary
As the prevalence of obesity at younger ages increases, people are living longer with obesity. We have recently shown that this has an increased risk of mortality and diabetes. In this project we will look at the extent to which an increasing length of time lived with obesity is also associated with increased risks of hypertension, heart disease, cancer, arthritis and disability. We will also look at the effect of this increasing duration on the overall health of Australian adults.
Home, Family And Socioeconomic Influences On Obesity-related Behaviours
Funder
National Health and Medical Research Council
Funding Amount
$304,874.00
Summary
Preventing obesity in children is a national health priority. Obesity promoting behaviours are established early in life, develop from childhood into adulthood, and are difficult to change. Parents play an important role in shaping the environments that either prevent or encourage obesity in children. This project aims to inform obesity prevention initiatives in Australian children and their families, and particularly among those at high risk due to their low socioeconomic position.