Effectiveness, Cost-effectiveness And Cost-benefit Of A Single Annual Professional Intervention For The Prevention Of Childhood Dental Caries In A Remote Rural Indigenous Community
Funder
National Health and Medical Research Council
Funding Amount
$1,050,869.00
Summary
The aim of the study is to reduce the high prevalence of tooth decay in children in a remote, rural Indigenous community, by application of a single annual dental preventive intervention. Most dental preventive interventions require regular re-application (3 monthly), which is not possible in resource constrained communities. Importantly, the study will assess cost-benefit and cost-effectiveness for broader implementation across similar communities in Australia and internationally.
Chronic Kidney Disease Centre Of Research Excellence
Funder
National Health and Medical Research Council
Funding Amount
$2,606,487.00
Summary
The Chronic Kidney Disease Centre of Research Excellence (CKD.CRE) is an Australian first, dedicated to the improvement of CKD knowledge and management across the health care spectrum. With five research streams, the CKD.CRE will establish a national surveillance network, support improved detection in primary care, inform on renal supportive care and on rationalised resource utilisation. In addition, the CKD.CRE will conduct biomarker research and will establish Australia’s first CKD BioBank.
Immuno-polymeric Drugs For Prostate Cancer Therapy
Funder
National Health and Medical Research Council
Funding Amount
$626,995.00
Summary
Prostate cancer is the most common cancer in men over 50 and the second most frequent cause of cancer deaths in Western society. Docetaxel is the first line of chemotherapy when other intervention strategies are unsuccessful, but 30% of patients suffer from severe side-effects. To address this problem, we will utilise carriers for docetaxel that directly target prostate tumours using a novel antibody approach. This increases accumulation at the tumour site while decreasing off-target toxicity.
SCALE-C: Strategies For Hepatitis C Testing And Treatment In Aboriginal Communities That Lead To Elimination
Funder
National Health and Medical Research Council
Funding Amount
$2,175,170.00
Summary
Prevalence of hepatitis C infection within the Aboriginal population is among the highest of any identifiable population in Australia. Highly effective, direct-acting antiviral (DAA) therapy, and their listing on the PBS in 2016 has revolutionised HCV clinical management in Australia. The SCALE-C study will evaluate an established test and treat model to rapidly scale-up DAA within four Aboriginal communities to determine both impact on community prevalence and ongoing transmission.
Population Health Planning For Rural Medicare Locals: Evaluating A Community Participation Method For Delivering Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$438,587.00
Summary
The study, in six communities, will evaluate whether an evidenced based method of rural community participation from the UK translates to assist healthcare planning by Medicare Locals. Medicare Locals must involve local people in designing services to improve health, but lack methods to do this. The focus of the study is oral health, a major issue in rural areas. The study evaluates whether new services are designed and implemented and whether there is change to health knowledge and behaviours.
Consumer Directed Care In Residential Aged Care: Transforming Practice Through The Resident At The Centre Of Care (RCC) Program
Funder
National Health and Medical Research Council
Funding Amount
$836,087.00
Summary
The impending introduction of Consumer Directed Care (CDC) into Residential Aged Care Facilities (RACFs) will require organisations to respond rapidly in both ‘mindset’ and service delivery to radically change the nature of their current care practices. This project will allow our industry partners to implement and evaluate a CDC model of care that, if successful, will lead to a sustainable site specific implementation plan of CDC for RACFs across Australia with better outcomes for residents.
Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliance ....Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliances with the government, industry and community partners will develop a practice framework to prevent everyday harms and the escalation to abuse, and to promote safety and wellbeing. The research has policy benefits for capacity-building in the sector to act on the rights and voices of people with disability. Read moreRead less
Tropical Infectious Diseases - Pathogenisis And Vaccine Research
Funder
National Health and Medical Research Council
Funding Amount
$7,311,989.00
Summary
The diseases on which three themes of the work proposed centre, malaria, streptococcal diseases and scabies are infectious diseases largely affecting indigenous people in various parts of the world on a massive scale, for which there are no vaccines. The aim of the work is to develop vaccines or other biological prevention measures against each of these diseases and the problems that need to be solved are similar. The team includes senior experts on thebiology of infectious diseases with long hi ....The diseases on which three themes of the work proposed centre, malaria, streptococcal diseases and scabies are infectious diseases largely affecting indigenous people in various parts of the world on a massive scale, for which there are no vaccines. The aim of the work is to develop vaccines or other biological prevention measures against each of these diseases and the problems that need to be solved are similar. The team includes senior experts on thebiology of infectious diseases with long histories of collaboration as well as younger members with impressive credentials that are new to the collaboration. The fourth theme of the work proposed is concerned with inventive new ways of making such vaccines by novelchemical methods. It has already been the subject of published collaborative work onstreptococcal disease and is equally applicable to the other themes.Read moreRead less
Evaluation Of Transdiagnostic Versus Disorder-Specific, Internet-Based Cognitive-Behaviour Treatment Of Anxiety Disorders In Young People
Funder
National Health and Medical Research Council
Funding Amount
$488,626.00
Summary
Traditionally, youth anxiety programs have adopted a generic approach where the same treatment program is used regardless of the particular anxiety disorder. The failure to tailor treatment to the specific anxiety disorder may partly explain why a significant proportion of young people fail to respond to such treatments. We propose that a disorder-specific approach will more effective than a generic program in internet-based therapy for youth anxiety.
Discovery Early Career Researcher Award - Grant ID: DE220100903
Funder
Australian Research Council
Funding Amount
$451,885.00
Summary
Charitable triad: How donors, beneficiaries, & fundraisers influence giving. This project aims to test a new model of charitable giving to examine how donors, beneficiaries, and fundraisers together influence donor decisions. Until now, no holistic model has existed to explain donor behaviour: past research has focused on donors but neglected beneficiaries and fundraisers. This project is expected to provide evidence for a new bedrock theory of philanthropy. Findings can also inform practitioner ....Charitable triad: How donors, beneficiaries, & fundraisers influence giving. This project aims to test a new model of charitable giving to examine how donors, beneficiaries, and fundraisers together influence donor decisions. Until now, no holistic model has existed to explain donor behaviour: past research has focused on donors but neglected beneficiaries and fundraisers. This project is expected to provide evidence for a new bedrock theory of philanthropy. Findings can also inform practitioner toolkits, offering advice to nonprofits on how to raise money effectively by understanding how the particular organisation and its beneficiaries can influence donor decisions. By helping ensure the survival of charities, this research will contribute to the delivery of essential social services that benefit many Australians.Read moreRead less