Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Arbovirus Activation And Modulation Of NLRP3 Inflammasome
Funder
National Health and Medical Research Council
Funding Amount
$779,720.00
Summary
This project aims to establish how mosquito borne viruses such as Ross River and dengue viruses interacts with the human host to cause disease, including how the virus evades the host’s immune response to persist and cause disease for prolonged periods. Knowing how differences in the virus and the host’s immune system interplay to cause asymptomatic to severely disabling disease will assist in devising new treatments and prevention programs to lessen the impact of these diseases in Australia.
Mosquito-borne alphaviruses such as Ross River and chikungunya viruses cause widespread epidemics and exert extreme pressure on the public health systems of affected regions. Alphaviruses spreads to joints and triggers a severe disease in those affected. There are no effective treatments or vaccines. The project will investigate virus-host interaction at the bite site. The outcome will be new knowledge to treat infection at the mosquito bite site to prevent joint disease.
Trends in Time: Work, Family and Social Policy in Australia 1992-2006. This project will contribute to the national priority goal of 'strengthening Australia's social and economic fabric to help families and individuals live healthy, productive, and fulfilling lives', within the National Research Priority of 'promoting good health and well being for all Australians'. It will provide sound new evidence for effective strategies fostering the policy goals of reducing stress on families, maintaining ....Trends in Time: Work, Family and Social Policy in Australia 1992-2006. This project will contribute to the national priority goal of 'strengthening Australia's social and economic fabric to help families and individuals live healthy, productive, and fulfilling lives', within the National Research Priority of 'promoting good health and well being for all Australians'. It will provide sound new evidence for effective strategies fostering the policy goals of reducing stress on families, maintaining fertility and encouraging women into paid work. Identifying measures that most support men and women to balance work-family commitments, to spend adequate time with their children and social networks, and most facilitate female workforce participation, will promote national wellbeing. Read moreRead less
Novel Insights Into The Pathobiology Of Alphavirus Infections
Funder
National Health and Medical Research Council
Funding Amount
$827,660.00
Summary
Infections with mosquito-borne viruses are increasing at an alarming rate worldwide. Ross River virus is endemic in parts of Australia, PNG and Pacific islands, while chikungunya virus is distributed globally and causes recurrent pandemics that involve millions of people. These viruses cause severe musculoskeletal disease for several months after infection. This project aims to establish how these viruses interact with the human host to cause disease and may provide a basis for new treatments.
Discipline, Morale and Winning Wars: Understanding the Relationships Between Discipline and Combat Performance in Low-Intensity Conflict. Discipline and morale are key elements in combat performance, particularly in Low-Intensity Conflict (LIC). This project examines the relationships between discipline, morale and combat performance using the Australian Army in Vietnam as a case study. It provides insights into better understanding and managing discipline and morale to produce and sustain comba ....Discipline, Morale and Winning Wars: Understanding the Relationships Between Discipline and Combat Performance in Low-Intensity Conflict. Discipline and morale are key elements in combat performance, particularly in Low-Intensity Conflict (LIC). This project examines the relationships between discipline, morale and combat performance using the Australian Army in Vietnam as a case study. It provides insights into better understanding and managing discipline and morale to produce and sustain combat performance. It assists the Army to avoid the negative effects of failures in discipline and morale that produced the My Lai massacre and the Abu Ghraib fiasco. It also helps position Australia internationally as a contributor to the better understanding of LIC, and fills a gap in Australian historiography of war.Read moreRead less
Understanding Low-Intensity Conflict. Since 1945, Low-Intensity Conflict (LIC) has become the dominant form of warfare. Conventional armies have a poor record of success in fighting LIC. This project uses the records of the Australian Army's operations in the Vietnam War to better understand it's operational performance there and to unearth insights into the conduct of LIC. The project has the potential to reduce casualties, both military and civilian, and assist the Army in selecting new war-fi ....Understanding Low-Intensity Conflict. Since 1945, Low-Intensity Conflict (LIC) has become the dominant form of warfare. Conventional armies have a poor record of success in fighting LIC. This project uses the records of the Australian Army's operations in the Vietnam War to better understand it's operational performance there and to unearth insights into the conduct of LIC. The project has the potential to reduce casualties, both military and civilian, and assist the Army in selecting new war-fighting technologies, designing training and developing doctrine for future LIC. The project will raise Australia's profile in theorising about this troubling but increasingly common form of warfare.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detaile ....Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detailed quantitative and qualitative data on the challenges and needs of older LGBTI Australians and service providers, and develop essential resources so policymakers and service providers can reduce older LGBTI Australians’ health disparities.Read moreRead less
Completing the Gallipoli story: Researching Turkish Archives for a More Comprehensive History. Both Australia and Turkey see the Gallipoli Campaign as a defining event. Australian perceptions of the Campaign are based on C.E.W. Bean's Official History and a number of popular publications. Yet, despite the vast collection of material held in Turkish archives, existing accounts give scant attention to Turkish operations leaving the story incomplete. This project will rectify that imbalance by loca ....Completing the Gallipoli story: Researching Turkish Archives for a More Comprehensive History. Both Australia and Turkey see the Gallipoli Campaign as a defining event. Australian perceptions of the Campaign are based on C.E.W. Bean's Official History and a number of popular publications. Yet, despite the vast collection of material held in Turkish archives, existing accounts give scant attention to Turkish operations leaving the story incomplete. This project will rectify that imbalance by locating and translating key documents-battlefield reports and signals, War Ministry communications, records of prisoner interrogations, aircraft logs and diaries. The result will be a comprehensive history that will contribute to the deepening relationship between Australia and Turkey as we approach the centenary of the Campaign. Read moreRead less