Gas Phase Studies to Catalyze a Better Understanding of Metal Reactivity. The proposed research will increase knowledge of fundamental questions related to the mechanisms of catalysis and metal ion reactivity. The insights gained will be an important addition to the knowledge base of our culture, both nationally and in the wider international context. We note that research into the behaviour and design of catalysts is a burgeoning field which reflects the great importance of this area in the int ....Gas Phase Studies to Catalyze a Better Understanding of Metal Reactivity. The proposed research will increase knowledge of fundamental questions related to the mechanisms of catalysis and metal ion reactivity. The insights gained will be an important addition to the knowledge base of our culture, both nationally and in the wider international context. We note that research into the behaviour and design of catalysts is a burgeoning field which reflects the great importance of this area in the international scientific community. Our proposal will add to fundamental knowledge and may also result in practical applications. More importantly, we will train and equip talented young people with a spectrum of skills which will make them well placed to meet the demand for highly skilled professional scientists.Read moreRead less
A new molecular platform for catalytic synthesis of heterocycles. This project aims to address the lack of efficient methods to prepare cyclic molecules of biological relevance by utilising novel molecular platforms developed in our laboratories. This project expects to generate new cyclic molecules using these innovative molecular platforms by employing catalysts to reduce raw material and energy cost. The expected outcomes of this project include enhanced chemical technology to prepare cyclic ....A new molecular platform for catalytic synthesis of heterocycles. This project aims to address the lack of efficient methods to prepare cyclic molecules of biological relevance by utilising novel molecular platforms developed in our laboratories. This project expects to generate new cyclic molecules using these innovative molecular platforms by employing catalysts to reduce raw material and energy cost. The expected outcomes of this project include enhanced chemical technology to prepare cyclic molecules of pharmaceutical importance and the training of highly skilled PhD students. This should provide significant benefits, such as increased capacity for the development of new pharmaceuticals and advanced materials.Read moreRead less
Gas Phase Reactivity of Charged Peptide and DNA Radicals: Fundamentals and Applications. Radicals derived from the "molecules of life", proteins and DNA, play both beneficial (e.g. enzyme catalysis) and deleterious roles (e.g. protein and DNA damage associated with disease). Two electrospray ionisation mass spectrometry approaches have been discovered to generate charged radicals of related models systems (e.g. peptides and nucleobases). The gas phase chemistry of these species is a largely unch ....Gas Phase Reactivity of Charged Peptide and DNA Radicals: Fundamentals and Applications. Radicals derived from the "molecules of life", proteins and DNA, play both beneficial (e.g. enzyme catalysis) and deleterious roles (e.g. protein and DNA damage associated with disease). Two electrospray ionisation mass spectrometry approaches have been discovered to generate charged radicals of related models systems (e.g. peptides and nucleobases). The gas phase chemistry of these species is a largely unchartered area! We will examine the fundamental chemistry (unimolecular and bimolecular reactions) of these systems and build upon some exciting preliminary results which suggest potential applications (e.g. as a proteomics tool to sequence and distinguish between leucine and isoleucine residues in peptides).Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100034
Funder
Australian Research Council
Funding Amount
$3,574,272.00
Summary
ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with ....ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with new products and processes with strong export potential, and the ability to respond to the market pressures, underpinned by green chemistry and sustainable principles. Resulting benefits include increased competitiveness for Australia's manufacturing industry, jobs, social as well as environmental benefitsRead moreRead less
Industrial Transformation Research Hubs - Grant ID: IH200100023
Funder
Australian Research Council
Funding Amount
$4,950,000.00
Summary
ARC Research Hub for Innovative Nitrogen Fertilisers and Inhibitors. This Hub aims to transform agriculture by delivering a new class of nitrogen (N) fertilisers and inhibitors designed to stem the 50-80% losses to the environment in current products. It is intended to generate new knowledge and valuable intellectual property in controlled released and coated N fertiliser products using a novel co-design process involving representatives of the whole value chain from product design through to va ....ARC Research Hub for Innovative Nitrogen Fertilisers and Inhibitors. This Hub aims to transform agriculture by delivering a new class of nitrogen (N) fertilisers and inhibitors designed to stem the 50-80% losses to the environment in current products. It is intended to generate new knowledge and valuable intellectual property in controlled released and coated N fertiliser products using a novel co-design process involving representatives of the whole value chain from product design through to validation and adoption. The project estimates possible 20% gains in efficiency of N use, delivering large costs savings, improved productivity, increased profitability and decreased environmental impacts, helping the Australian food and agribusiness sector to reach its 2030 target of $100B value added.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH170100020
Funder
Australian Research Council
Funding Amount
$2,641,142.00
Summary
ARC Research Hub for Processing Lignocellulosics into High Value Products. The ARC Research Hub for Processing Lignocellulosics into High Value Products aims to convert renewable and readily-available biomass material and waste streams from the Australian Pulp, Paper and Forest Industry into new, high-value products that are in high demand in existing and developing markets. The Research Hub will translate leading scientific discoveries in biomass conversion into the manufacture of advanced mate ....ARC Research Hub for Processing Lignocellulosics into High Value Products. The ARC Research Hub for Processing Lignocellulosics into High Value Products aims to convert renewable and readily-available biomass material and waste streams from the Australian Pulp, Paper and Forest Industry into new, high-value products that are in high demand in existing and developing markets. The Research Hub will translate leading scientific discoveries in biomass conversion into the manufacture of advanced materials that can be used in the industries of the future. Research aims to identify new applications and products. They will be derived from lignocellulose through the advent of new smart paper packaging, green chemical and materials with unique properties. Benefits will flow to the pharmaceutical, chemicals, plastics and food packaging industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100502
Funder
Australian Research Council
Funding Amount
$424,875.00
Summary
Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzy ....Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzyme catalysts to rapidly generate complex molecular structures. These novel molecules can be readily converted into pharmaceuticals and agrochemicals leading to advancements in the bio-enabled production and application of organic molecules in these vital fields. Read moreRead less
Stabilisation of Titania Pigment Slurries During Processing. This project aims to improve the stabilisation properties of titania pigment slurries during production. Current polyphosphate dispersants used by Tiwest are unstable under processing conditions. Tailored, robust dispersing reagents will therefore be investigated in order to provide improved stabilisation of pigments during processing. Enhanced understanding of the dispersing reagents interaction with the titania pigment surface and th ....Stabilisation of Titania Pigment Slurries During Processing. This project aims to improve the stabilisation properties of titania pigment slurries during production. Current polyphosphate dispersants used by Tiwest are unstable under processing conditions. Tailored, robust dispersing reagents will therefore be investigated in order to provide improved stabilisation of pigments during processing. Enhanced understanding of the dispersing reagents interaction with the titania pigment surface and the subsequent stability of the pigment will allow advances in processing and consequently improved final products. The potential growth in market share, by improved product performance, is in excess of $50M pa.Read moreRead less
Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This projec ....Diatom lipids to reveal sea-ice history in remote Antarctic regions. This project aims to understand seasonal Antarctic sea-ice extent using molecular, geochemical, elemental and genomic characteristics of specific marine phytoplankton (diatoms). Little is known of the seasonal sea-ice variation and the position of the summer sea-ice extent a million years before satellite records, but this information is critical to determining air-sea gas exchange and ecosystem food web regulation. This project will unite geochemical and biological approaches to provide the data to improve past Antarctic ecosystem and climate models where sea-ice data is missing. Studying diatom biomarkers in deep sea cores from Australia’s Southern Ocean will redefine knowledge of Antarctic climate and provide data necessary to improve global ecosystem and climate models.Read moreRead less
Fire and rain: Drivers of deep-time ecosystem assembly in Australia. This project aims to investigate the influence of bushfires and shifting rainfall patterns on the development of Australia’s dominant ecosystems. By combining a range of novel geochemical, isotopic and palaeontological techniques, this research seeks to reveal the causes and consequences of Australia’s transformation from a forested to mainly open landscape of grassland, shrubland and savannah. The expected outcome is detailed ....Fire and rain: Drivers of deep-time ecosystem assembly in Australia. This project aims to investigate the influence of bushfires and shifting rainfall patterns on the development of Australia’s dominant ecosystems. By combining a range of novel geochemical, isotopic and palaeontological techniques, this research seeks to reveal the causes and consequences of Australia’s transformation from a forested to mainly open landscape of grassland, shrubland and savannah. The expected outcome is detailed knowledge of how changes in fire and rain shaped the ecology and evolution of plants and animals. This knowledge is key to understanding how Australian ecosystems function and to protecting their cultural, economic and environmental values, especially as climate and fire regimes continue to change into the future.Read moreRead less