Discovery Early Career Researcher Award - Grant ID: DE150100517
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Organocatalysis: A New Horizon for Synthesis of Organic Structures. The current technologies to synthesise organic substances, an important part of human life, often involve the use of excess amounts of reagents or precious and toxic metal catalysts, which incur high production costs and severe environmental impact. This project aims to use organocatalysis, chemical processes catalysed by stable, small, easily accessible, non-metallic organic compounds, to find a solution for these issues. Novel ....Organocatalysis: A New Horizon for Synthesis of Organic Structures. The current technologies to synthesise organic substances, an important part of human life, often involve the use of excess amounts of reagents or precious and toxic metal catalysts, which incur high production costs and severe environmental impact. This project aims to use organocatalysis, chemical processes catalysed by stable, small, easily accessible, non-metallic organic compounds, to find a solution for these issues. Novel organocatalytic methods will be designed and developed in order to promote environmentally friendly, highly efficient and selective chemical procedures for low cost production of laboratory organic substances and application in the industrial synthesis of potential agrochemicals and medicinal agents.Read moreRead less
Synthesis and Production of High Value Pyridines Combining the Concepts of Alternative Reaction Media and Process Intensification. This project aims to develop novel syntheses and process route for substituted pyridines by bringing together expertise in the fields of green chemistry and process intensification. Minimisation of waste, energy efficiency, and improved selectivity and control will be the key process and chemistry targets, which will produce high value compounds. Traditional approach ....Synthesis and Production of High Value Pyridines Combining the Concepts of Alternative Reaction Media and Process Intensification. This project aims to develop novel syntheses and process route for substituted pyridines by bringing together expertise in the fields of green chemistry and process intensification. Minimisation of waste, energy efficiency, and improved selectivity and control will be the key process and chemistry targets, which will produce high value compounds. Traditional approaches use organic solvents and preformed salts which are costly, generate waste and the processes are energy intensive due to poor selectivity, low yield and extensive separation steps. This is a generic investigation which will have wide ranging applications in the pharmaceutical, energy and advanced electronic industries.Read moreRead less
Application of process intensification on rotating surfaces (PIRS) in organic synthesis. Process intensification technologies in the form of SDP and RTP are new to Australia and present many opportunities for carrying out the synthesis of organic compounds. They have remarkable versatility in being able to control chemical reactions with greater selectivity than using classical batch technology, at the same time allowing access to new compounds. Moreover, the technologies embrace the principles ....Application of process intensification on rotating surfaces (PIRS) in organic synthesis. Process intensification technologies in the form of SDP and RTP are new to Australia and present many opportunities for carrying out the synthesis of organic compounds. They have remarkable versatility in being able to control chemical reactions with greater selectivity than using classical batch technology, at the same time allowing access to new compounds. Moreover, the technologies embrace the principles of green chemistry in minimising the generation of waste, while operating under continuous flow which is destined to be more attractive to industry. This is likely in the fine chemicals sector, and in drug discovery. The project will provide first-rate research training and promote Australian science. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882634
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Integrated Process Intensification Facility. The new equipment will provide a unique facility for process intensification (PI). No other techniques are capable of controlling features of nano-particles (size, shape, agglomeration, phases and defects) under continuous flow, which is essential for applications in nano-technology. There are unique capabilities of PI in chemical synthesis, including drug development and drug discovery. Overall, applications of PI cover health care products, device t ....Integrated Process Intensification Facility. The new equipment will provide a unique facility for process intensification (PI). No other techniques are capable of controlling features of nano-particles (size, shape, agglomeration, phases and defects) under continuous flow, which is essential for applications in nano-technology. There are unique capabilities of PI in chemical synthesis, including drug development and drug discovery. Overall, applications of PI cover health care products, device technology, and more, for the benefit of the community at large. The facility will foster a more innovative research culture and provide excellent research training at the highest international level, and will provide a platform to foster greater links with industry.Read moreRead less
Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translat ....Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translated into molecular assembly line syntheses in a single unit or a series. Such syntheses should provide a versatile toolbox for molecular transformations, under continuous flow conditions where scalability is addressed upfront. This will be attractive to industry and minimise effects on the environment.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100034
Funder
Australian Research Council
Funding Amount
$3,574,272.00
Summary
ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with ....ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with new products and processes with strong export potential, and the ability to respond to the market pressures, underpinned by green chemistry and sustainable principles. Resulting benefits include increased competitiveness for Australia's manufacturing industry, jobs, social as well as environmental benefitsRead moreRead less
Modular Vortex Fluidic Mediated Molecular Transformations. The project aims to develop the use of electric and magnetic fields to control chemical and biochemical reactions in high shear thin films under readily scalable continuous flow conditions to then be able to precisely build complex functional molecules. Depending on the orientation, strength and frequency of external electric and magnetic fields, and novel shear stress induced electric fields in solution, rates of reactions can be enhanc ....Modular Vortex Fluidic Mediated Molecular Transformations. The project aims to develop the use of electric and magnetic fields to control chemical and biochemical reactions in high shear thin films under readily scalable continuous flow conditions to then be able to precisely build complex functional molecules. Depending on the orientation, strength and frequency of external electric and magnetic fields, and novel shear stress induced electric fields in solution, rates of reactions can be enhanced, with higher yields and tunable selectivity, and reduced waste and energy usage, which is not possible using traditional batch processing. This will be translated into molecular assembly line processing and the development of a new synthetic toolbox, with applications in preparing pharmaceuticals.
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Integrated approach to self assembled molecular capsules. Process intensification technologies in the form of spinning disc and rotating tube processing are new to Australia and present many opportunities for both carrying out the synthesis of organic compounds and in fabricating nanomaterials. The ensuing nanotechnological applications are more benign in approach then other fabrication techniques, minimising the generation of waste at the same time under continuous flow which is likely to be mo ....Integrated approach to self assembled molecular capsules. Process intensification technologies in the form of spinning disc and rotating tube processing are new to Australia and present many opportunities for both carrying out the synthesis of organic compounds and in fabricating nanomaterials. The ensuing nanotechnological applications are more benign in approach then other fabrication techniques, minimising the generation of waste at the same time under continuous flow which is likely to be more attractive to industry. Proposed applications such as drug delivery, catalysis, smart materials and device technology are expected to foster industrial collaborations. The project will provide first-rate research training and promote Australian science through the development of these new technologies.Read moreRead less
The development of tools to study carbohydrate-processing enzymes implicated in human disease. Diseases caused by improper function of carbohydrate-processing enzymes are a major health burden. This research aims to find ways to restore the function of these enzymes bringing a better quality of life to people suffering from these diseases.