Centre Of Research Excellence In Eradicating Food Allergy: Prevention, Cure And Reducing Adverse Events
Funder
National Health and Medical Research Council
Funding Amount
$2,496,041.00
Summary
Australia has the highest reported rate of food allergy in the world. We aim to eradicate food allergy through improved prevention and cure, supported by evidence generated by our collaborative network of research. In addition, we aim to help prevent children with food allergy having anaphylaxis through improved public health policy and clinical pathways. As a second wave of the allergy epidemic, we are well positioned to turn back the tide of this newly emergent health threat to the public.
Mechanisms Of Glucocorticoid Resistance In Acute Lymphoblastic Leukaemia
Funder
National Health and Medical Research Council
Funding Amount
$547,970.00
Summary
Glucocorticoids are extremely active drugs used in the treatment of childhood acute lymphoblastic leukaemia (ALL), yet a proportion of patients respond poorly to therapy and exhibit resistance at relapse. Clinically relevant mechanisms of glucocorticoid resistance are poorly understood, principally due to lack of appropriate experimental models. This project will reveal novel mechanisms of drug resistance in childhood leukaemia and lead to novel therapeutic strategies to improve outcome.
Mechanisms Of Induction And Progression Of Childhood Asthma: Investigations In A Mouse Model
Funder
National Health and Medical Research Council
Funding Amount
$517,586.00
Summary
This project investigates how certain respiratory viral infections in very young children might predispose to developing asthma, and how inflammation in the airways in asthma might then worsen. The experimental work, which will use unique mouse models developed in the laboratories of the chief investigators, will focus on changes in genes that control the pattern of immune response to allergens and that regulate the progression of inflammation.
A Multi-setting Intervention To Reduce Sedentary Behaviour, Promote Physical Activity And Improve Childrens Health
Funder
National Health and Medical Research Council
Funding Amount
$860,343.00
Summary
Sedentary behaviours and physical inactivity play a major role in the rising prevalence of obesity among children in Australia. This intervention study will take place in the school and family settings which play a critical role in shaping children's health behaviours. The objective is to determine whether a 2-year behavioural intervention reduces sedentary behaviour and promotes physical activity and results in improved health among 8-9 year old children.
Honesty and efficiency in the provision of expert services: doctors and other experts as participants in economic experiments. Experts serve us when we see the doctor, the financial planner or the car mechanic. In all these case the expert can take advantage of his superior knowledge and sell us something we do not need. This research will inform policy makers about the underlying motives of real world experts and allow them to design better institutions.
Older workers & psychological contracts: A dynamic perspective. This project aims to track the trajectories of older workers’ psychological contracts that shape their give-and-take with the organisation. Little is understood about how these psychological contracts change as older workers continue to pursue work through their fifth, sixth, seventh and eighth decades of life. This project tracks older workers over intensive, repeated in-depth interviews and a large-scale longitudinal panel study. ....Older workers & psychological contracts: A dynamic perspective. This project aims to track the trajectories of older workers’ psychological contracts that shape their give-and-take with the organisation. Little is understood about how these psychological contracts change as older workers continue to pursue work through their fifth, sixth, seventh and eighth decades of life. This project tracks older workers over intensive, repeated in-depth interviews and a large-scale longitudinal panel study. The outcomes fill significant gaps in our understanding of older workers’ needs and orientation toward work, and identify the age-related changes and organisational practices that spur older workers to sustain a strong trajectory of productive participation in the workforce.Read moreRead less
Centre Of Research Excellence On Sitting Time And Chronic Disease Prevention – Mechanisms, Measurement And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$2,657,874.00
Summary
Australian research has identified serious health consequences arising from the 7 to 10 hours of daily sitting that most people do, especially in relation to ‘diseases of inactivity’ – type 2 diabetes, coronary heart disease and breast and colon cancer – that are an unwelcome burden on individuals, families and health systems. This new research examines the practical feasibility and the preventive-health benefits of changing children’s and adults’ sitting time in schools, workplaces and the home ....Australian research has identified serious health consequences arising from the 7 to 10 hours of daily sitting that most people do, especially in relation to ‘diseases of inactivity’ – type 2 diabetes, coronary heart disease and breast and colon cancer – that are an unwelcome burden on individuals, families and health systems. This new research examines the practical feasibility and the preventive-health benefits of changing children’s and adults’ sitting time in schools, workplaces and the home environment.Read moreRead less
Sitting Less And Moving More: Population Health Research To Understand And Influence Sedentary Behaviour
Funder
National Health and Medical Research Council
Funding Amount
$6,367,518.00
Summary
The majority of Australian adults spend most of their waking hours sitting: at home, at work, and in their cars; most do not participate in exercise or sport. This leads to weight gain and to diseases of inactivity (particularly diabetes, heart disease, cancer and depression). New research will measure sitting time and the physical activity in people's daily lives, what factors encourage inactivity, and how to increase activity levels, especially among the ageing 'baby boomer' population.
Serving the greater good: using 'Servant Leadership' to build ethical and engaging work practices. The project will result in the first organisational application in Australia of a leadership development program based on scientific foundations of the 'Servant Leadership' framework. The outcomes will benefit organisations of all types in developing the leadership capabilities required to create ethical, positive, and sustainable work environments.
The use of nudges as a local government environmental policy instrument. This project aims to design and rigorously test a range of behavioural nudges to improve the environmental behaviour of residents in the ACT, with a focus on adoption of low carbon technologies and the use of public transport. In partnership with the ACT Government, the proposal leverages recent research on cognitive biases to develop novel interventions and evaluate their effects via randomised controlled trials. Expected ....The use of nudges as a local government environmental policy instrument. This project aims to design and rigorously test a range of behavioural nudges to improve the environmental behaviour of residents in the ACT, with a focus on adoption of low carbon technologies and the use of public transport. In partnership with the ACT Government, the proposal leverages recent research on cognitive biases to develop novel interventions and evaluate their effects via randomised controlled trials. Expected outcomes include new concepts for citizen-government interactions; advanced knowledge in public policy and behavioural economics; a new statistical programming tool; new methods to optimise policy and practice; and positive environmental and economic impacts for local governments and individuals.Read moreRead less