Airway Epithelial Barrier Function, Asthma And Aero-allergen Sensitization.
Funder
National Health and Medical Research Council
Funding Amount
$527,886.00
Summary
There is a strong association between allergy and asthma. This association been almost universally assumed to be causative. However, recent evidence suggests an alternative explanation ie., that the abnormal epithelium in asthma allows or facilitates sensitization to airborne allergens. This project will test this alternative hypothesis using human lung tissue and an animal model.
Participate-CP: Optimising Participation In Physically Active Leisure For Children With Cerebral Palsy: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,014,872.00
Summary
In Australia, 35,000 people have cerebral palsy, who compared to able-bodied peers, are less active with a greater risk of chronic, life-limiting health conditions. There are currently no effective interventions for children with cerebral palsy to increase their physical activity and participation in active leisure activities. We have promising data about a new intervention, called Participate-CP, which we will test in 80 children with cerebral palsy and compare results to usual therapy care.
Optimisation Of Antimicrobial Therapy For Severe Bacterial Infections In Neonates And Young Children In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$943,865.00
Summary
This study aims to provide important information on the way young Papua New Guinean children with serious bacterial infections handle antibiotics, including newer agents that may be required if bacterial resistance is confirmed or increases. The data will be used to optimise treatment, thus reducing mortality and potential adverse drug effects, in PNG nad other tropical countries, and may have implications for the developed world as well.
Enhancing Clinical Management Of Paediatric Malaria In Endemic Areas With Transmission Of Multiple Plasmodium Species
Funder
National Health and Medical Research Council
Funding Amount
$867,511.00
Summary
Malaria remains a major problem for children in developing countries especially where different types of the disease are common. This set of complementary studies, based at an established research site in PNG aims to develop new treatment strategies for childhood malaria. A novel method of giving medicine via a spray under the tongue for sick children before arrival at hospital and modified dosing schedules of an old drug used for treating parasites hidden in the liver will be studied.
The Sexual Health And Attitudes Of Australian Prisoners
Funder
National Health and Medical Research Council
Funding Amount
$1,605,706.00
Summary
The second Sexual Health and Attitudes of Australian Prisoners study will be the largest population-based survey of prisoners’ sexual health, attitudes and behaviour undertaken in Australia. it has been nearly 10 years since the first survey. The 2nd survey will expand survey coverage and examine vulnerable prisoner subgroup, and provide up-to-date evidence essential to sexual and reproductive health policy and practice for this growing and disadvantaged population.
A Life Course Approach To Characterising And Predicting Inactivity And Sedentary Behaviour Of Young Adults
Funder
National Health and Medical Research Council
Funding Amount
$302,006.00
Summary
Poor activity habits are expected to overtake smoking as the leading preventable cause of health burden in Australia. Poor activity habits increase the risk for a shorter life and many health problems such as heart disease, some cancers and diabetes. Young adulthood is an important time for individuals to develop their lifestyle habits. This study will provide the first detailed description of the inactivity habits of Australians in their early 20s and factors we can target before adulthood to e ....Poor activity habits are expected to overtake smoking as the leading preventable cause of health burden in Australia. Poor activity habits increase the risk for a shorter life and many health problems such as heart disease, some cancers and diabetes. Young adulthood is an important time for individuals to develop their lifestyle habits. This study will provide the first detailed description of the inactivity habits of Australians in their early 20s and factors we can target before adulthood to encourage healthy habits.Read moreRead less
Rates, Patterns And Determinants Of Alcohol’s Harm To Others: A Cross-national Comparative Study
Funder
National Health and Medical Research Council
Funding Amount
$305,856.00
Summary
Alcohol causes harms to drinkers, and others around them, including spouses, children, family, friends, workmates and strangers. Australian and New Zealand work on alcohol’s harm to others is being replicated by the WHO in 7 countries (Chile, Nigeria, Sri Lanka, India, Thailand, Laos and Vietnam). We aim to analyse datasets from nine countries and compare the magnitude and patterning of problems across and within cultures – identifying opportunities for reducing harm from others’ drinking.
Reducing Prolonged Workplace Sitting Time In Office Workers: A Cluster-randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$524,613.00
Summary
Groundbreaking Australian research shows that sitting for too long, which is routine for most office workers, contributes to overweight and to a greater risk of developing diabetes and heart disease. In over 300 desk-bound office workers, this world-first study will assess the effectiveness of an innovative workplace program aimed at reducing and breaking up sitting time. It will identify practical ways for Australian office workers to minimise unhealthy effects of sitting too much at work.