Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239467
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
A portable laser scanning facility for geomatic data capture. Ground-based laser scaning is an emerging technology that promises to revolutionize spatial data capture for the geomatics industry due to its high data volume, accuracy and acquisition rate. This proposal brings together leading academics from Australasia to establish a laser scanning facility that will enhance existing projects and explore new avenues in geomatic research. The facility will impact on the research programs of partici ....A portable laser scanning facility for geomatic data capture. Ground-based laser scaning is an emerging technology that promises to revolutionize spatial data capture for the geomatics industry due to its high data volume, accuracy and acquisition rate. This proposal brings together leading academics from Australasia to establish a laser scanning facility that will enhance existing projects and explore new avenues in geomatic research. The facility will impact on the research programs of participating institutions in the fields of high-resolution thematic mapping and visualization, environmental geomatics, geomatic monitoring and geomatic engineering. Furthermore, the facility will allow Australasian universities to develop a knowledge base in this new and exciting technology.Read moreRead less
GABA(B) Receptor Modulation Of Gastrointestinal Function In Health And Disease By Alpha-Conotoxins
Funder
National Health and Medical Research Council
Funding Amount
$689,050.00
Summary
Chronic visceral pain is a common and debilitating condition arising from numerous diseases that affect our internal organs. There is a desperate need for more information about the mechanisms responsible for signalling chronic visceral pain to provide therapies and potentially find a cure for it. Our research focuses on ?-conotoxins (small peptides from marine cone snail venom) as novel potential therapeutic agents for the treatment of chronic visceral pain.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775614
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
National Electromagnetic Characterization Facility for Advanced Electronic and Biomaterials. The proposed Material Characterisation Facility using non-destructive methods will be unique to Australia. Precise characterisation of advanced materials such as dielectrics and superconductors using the facility will progress emerging technologies within the electronic and communication research area. The inclusion of a microwave scanning test bed within the laboratory will allow engineers, scientists, ....National Electromagnetic Characterization Facility for Advanced Electronic and Biomaterials. The proposed Material Characterisation Facility using non-destructive methods will be unique to Australia. Precise characterisation of advanced materials such as dielectrics and superconductors using the facility will progress emerging technologies within the electronic and communication research area. The inclusion of a microwave scanning test bed within the laboratory will allow engineers, scientists, biologists and medical scientists to safely detect the intrinsic electromagnetic properties of electronic materials and tumours in biological tissues or poor quality agricultural produce. This comprehensive material characterisation facility will therefore benefit the peoples of Australasia in many significant and diverse ways.Read moreRead less