Role Of Sphingolipid Signalling In Hepatic Insulin Resistance And Its Application In Prediction Of Risk For Type 2 Diabetes And Prediabetes
Funder
National Health and Medical Research Council
Funding Amount
$563,305.00
Summary
Type 2 diabetes is expected to reach epidemic proportions in the coming decades. Prediabetes is usually unrecognized and constitutes a major public health concern that needs earlier interventions, because the majority of prediabetic subjects proceed to T2D. We have identified an enzyme that plays an important role in insulin signalling. The possibility is that the level or activity of this enzyme is a potential biomarker of the prediabetes state and could be also used as a target
Genetic Biomarkers And Molecular Pathways For Migraine
Funder
National Health and Medical Research Council
Funding Amount
$273,988.00
Summary
Common migraine, is a frequent, debilitating and painful disorder that affects people during their most productive years (up to 25% of women and 8% of men). Our recent results indicate the presence of multiple genetic factors contributing towards migraine susceptibility. Utilising detailed migraine symptom and medication data, larger numbers of migraine cases and controls, and applying the latest genotyping and imputation technologies, we will identify novel genetic biomarkers and molecular path ....Common migraine, is a frequent, debilitating and painful disorder that affects people during their most productive years (up to 25% of women and 8% of men). Our recent results indicate the presence of multiple genetic factors contributing towards migraine susceptibility. Utilising detailed migraine symptom and medication data, larger numbers of migraine cases and controls, and applying the latest genotyping and imputation technologies, we will identify novel genetic biomarkers and molecular pathways for migraine.Read moreRead less