The role of the immune system in pain is emerging from recent discoveries, and may hold the key to novel pain treatments. Most people experience brief gut infections from food or contagion without long-term consequences. Many others suffer symptoms for years afterwards - probably the best example of immune-based pain. Our project investigates how immune cells communicate with sensory nerves, and how these communications change from both angles after gut infection or inflammation.
Transient Receptor Potential Channels (TRPs) As Transducers And Targets In Primary Visceral Afferents
Funder
National Health and Medical Research Council
Funding Amount
$669,130.00
Summary
Transient receptor potential, or TRP channels, are involved in generating many of the sensations we perceive, such as heat, cold, touch and pain. Some TRP channels are specialized to signal pain from visceral organs, which we must investigate if we are to find treatments for visceral pain, which are currently lacking.
Special Research Initiatives - Grant ID: SR0354693
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian e-Research Grid. The e-Research Grid program will research and implement core Grid technologies on APAC and partner's deployed HPC resources, to underpin a broad range of Australian research. The computer science CIs will form collaborative links with international programs, adapting developments to local circumstances. The applications-domain CIs will leverage those into their scientific simulations and databases, using grid integrative techniques and portals. Many CIs participate in ....Australian e-Research Grid. The e-Research Grid program will research and implement core Grid technologies on APAC and partner's deployed HPC resources, to underpin a broad range of Australian research. The computer science CIs will form collaborative links with international programs, adapting developments to local circumstances. The applications-domain CIs will leverage those into their scientific simulations and databases, using grid integrative techniques and portals. Many CIs participate in other RNs linking to their motivating applications, enhancing prospects for research and integration. They participate in the APAC Grid program, leveraging 75 HPC staff nationally. A key aim is interoperability with "real-world Grids": eg e-learning & e-health programs.Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less
Investigation and development of robust rule discovery and classification system. This research focuses on a national research priority, namely smart information use. The expected outcomes of the project will greatly advance intelligent system design, such as automatic decision making, fault detection and problem diagnosis, for finance, medical, telecom and many other areas. It has great potential for commercialisation and earning incomes for the future research. The publications will benefit th ....Investigation and development of robust rule discovery and classification system. This research focuses on a national research priority, namely smart information use. The expected outcomes of the project will greatly advance intelligent system design, such as automatic decision making, fault detection and problem diagnosis, for finance, medical, telecom and many other areas. It has great potential for commercialisation and earning incomes for the future research. The publications will benefit the future development of intelligent systems for dealing with missing data. This project directly supports a PhD student and two research assistants who will most likely continue their higher degree study. These contribute to regional tertiary education.Read moreRead less
Closing the loop between salience and brain activity. This project aims to understand how animals exposed to an abundance of highly complex information decide what to attend to, that is, how they determine visual saliency. The project will approach this question by systematically tracking visual decision-making in the smallest animal brains, in closed-loop virtual reality environment. This approach will uncover basic working principles applicable to any system that needs to pay attention in a vi ....Closing the loop between salience and brain activity. This project aims to understand how animals exposed to an abundance of highly complex information decide what to attend to, that is, how they determine visual saliency. The project will approach this question by systematically tracking visual decision-making in the smallest animal brains, in closed-loop virtual reality environment. This approach will uncover basic working principles applicable to any system that needs to pay attention in a visually cluttered world, from insects to humans or autonomous vehicles.Read moreRead less
ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the ....ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the financial system. It will enable Australian research in this area to match the scale and impact of similar research in other major international financial centres, and play an essential role in placing Australia among the world's leaders in financial markets related research.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561231
Funder
Australian Research Council
Funding Amount
$671,715.00
Summary
MRI GRID Computing Facility: Design, Optimisation and Image Processing. The MRI Grid Computing Facility provides the IT infrastructure to achieve effective e-research in the area of magnetic resonance (MR) imaging, a field of neuroscience research that revolutionizes the way brain diseases are identified and treated. The facility consists of a dedicated high performance grid compute engine, distributed visualisation workstations, and distributed data warehouse facilities. Software tools acc ....MRI GRID Computing Facility: Design, Optimisation and Image Processing. The MRI Grid Computing Facility provides the IT infrastructure to achieve effective e-research in the area of magnetic resonance (MR) imaging, a field of neuroscience research that revolutionizes the way brain diseases are identified and treated. The facility consists of a dedicated high performance grid compute engine, distributed visualisation workstations, and distributed data warehouse facilities. Software tools accessible through the Internet will enable researchers to archive, retrieve and exchange data and software; access distributed MR image databases and the latest MR image analysis tools; schedule analysis tasks on the grid compute engine, the outcomes of which will be visualized by the visualization workstations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100158
Funder
Australian Research Council
Funding Amount
$348,026.00
Summary
A large-scale distributed experimental facility for the internet of things. This project aims to establish a large-scale, real-world experimental facility for the Internet of Things (IoT), which is currently missing in Australia, as well as in the rest of the world. The project is expected to be an essential instrument to achieve Australia’s leadership on key enabling technologies of the IoT, and to provide Australian research community with a unique platform for large-scale experimentation and ....A large-scale distributed experimental facility for the internet of things. This project aims to establish a large-scale, real-world experimental facility for the Internet of Things (IoT), which is currently missing in Australia, as well as in the rest of the world. The project is expected to be an essential instrument to achieve Australia’s leadership on key enabling technologies of the IoT, and to provide Australian research community with a unique platform for large-scale experimentation and evaluation of IoT technologies and services. The project will also serve as a vehicle for the education and training of Australia’s next generation of scholars and engineers, and contribute to Australia’s scientific visibility.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100017
Funder
Australian Research Council
Funding Amount
$3,703,664.00
Summary
ARC Training Centre for Integrated Operations for Complex Resources. This Training Centre aims to increase value in mining through clever applications of ‘lean processing’ and train the next generation of scientists and engineers in advanced sensors and data analytics in complex resources; knowledge priorities for the mining industry. Sensor information will be linked to the resource’s in-place knowledge to enable data analytics of all embedded knowledge. Processing can then be tuned to resource ....ARC Training Centre for Integrated Operations for Complex Resources. This Training Centre aims to increase value in mining through clever applications of ‘lean processing’ and train the next generation of scientists and engineers in advanced sensors and data analytics in complex resources; knowledge priorities for the mining industry. Sensor information will be linked to the resource’s in-place knowledge to enable data analytics of all embedded knowledge. Processing can then be tuned to resource attributes, maximising value ‘on the fly’. Benefits will include increasing certainty on product quality and maximising throughput and recovery. Outcomes will include new tools to rapidly model geological and geometallurgical uncertainty with sensor inputs, to track the resource to product and enhance interpretation.Read moreRead less