Understanding the implications of pandemic delays for the end of life. The untold toll of Covid-19 is emerging in ‘avoidable deaths’ linked to late(r) diagnosis or treatment due to pandemic-related delay. How delays are experienced and felt across families and communities requires urgent attention. This project aims to understand the implications of pandemic delay for dying and bereavement, including the sociocultural factors that shape experiences of illness and care amid delay. The significanc ....Understanding the implications of pandemic delays for the end of life. The untold toll of Covid-19 is emerging in ‘avoidable deaths’ linked to late(r) diagnosis or treatment due to pandemic-related delay. How delays are experienced and felt across families and communities requires urgent attention. This project aims to understand the implications of pandemic delay for dying and bereavement, including the sociocultural factors that shape experiences of illness and care amid delay. The significance of this project lies in its innovative sociological approach; expected outcomes include the generation of new knowledge on needs at the end of life that move across contexts and settings. Benefits include provision of findings that will inform social and health policy and practice improvements to enable good deaths.Read moreRead less
Understanding communication about advance care planning across the lifespan. This project aims to understand how people communicate about advance care planning for children, adolescents, and adults. This project expects to generate new knowledge by using leading social scientific and linguistic methods to analyse real-world advance care planning conversations and documents. Expected outcomes include detailed knowledge about challenges people encounter in these conversations and how to manage the ....Understanding communication about advance care planning across the lifespan. This project aims to understand how people communicate about advance care planning for children, adolescents, and adults. This project expects to generate new knowledge by using leading social scientific and linguistic methods to analyse real-world advance care planning conversations and documents. Expected outcomes include detailed knowledge about challenges people encounter in these conversations and how to manage these challenges. Over 170,000 Australians die each year, most from serious illness. This project should provide significant benefits to future initiatives for enhancing communication about advance care planning, especially in relation to young Australians, older Australians, and Australians with disabilities.Read moreRead less
Central nervous system cytokines and morphine analgesia. Morphine remains the drug of choice for the management of moderate-to-severe pain, however its clinical effectiveness is compromised by the fact that morphine's analgesic (pain reducing) efficacy becomes less effective the more it is administered.. This project will examine how analgesic tolerance develops from a completely new approach: Namely, how stimulation of the immune system within the central nervous system is a crucial factor in t ....Central nervous system cytokines and morphine analgesia. Morphine remains the drug of choice for the management of moderate-to-severe pain, however its clinical effectiveness is compromised by the fact that morphine's analgesic (pain reducing) efficacy becomes less effective the more it is administered.. This project will examine how analgesic tolerance develops from a completely new approach: Namely, how stimulation of the immune system within the central nervous system is a crucial factor in the development of tolerance. Modulation of analgesia by the immune system has not been systematically studied and provides a potentially fertile ground for the development of new techniques in the management of clinical pain.Read moreRead less
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
All-solid-state Z-scheme photocatalysts for water treatment. The project aims to develop high-performance Z-scheme photocatalysts by using two-dimensional (2D) semiconductors as building blocks for low-cost, highly-efficient pathogen inactivation and emerging pollutant degradation in stormwater treatment. The project expects to generate new fundamental knowledge in the area of photocatalyst design and Z-scheme photocatalytic system, and advance the application of photocatalytic oxidation in wate ....All-solid-state Z-scheme photocatalysts for water treatment. The project aims to develop high-performance Z-scheme photocatalysts by using two-dimensional (2D) semiconductors as building blocks for low-cost, highly-efficient pathogen inactivation and emerging pollutant degradation in stormwater treatment. The project expects to generate new fundamental knowledge in the area of photocatalyst design and Z-scheme photocatalytic system, and advance the application of photocatalytic oxidation in water treatment. The expected outcomes of the project include novel 2D Z-scheme photocatalysts and enhanced capacity in stormwater management.Read moreRead less
Hydrophobic particle recovery using permeable hydrophobic media. This project aims to solve an intractable problem in froth flotation. Bubbles will be replaced by permeable, hydrophobic media, minimising the viscous hydrodynamic resistance that limits ultrafine particle recovery. The project expects to generate new knowledge relating the efficacy of the novel media to its underlying physical structure, composition, geometry, and interfacial structure. Expected outcomes include a framework for de ....Hydrophobic particle recovery using permeable hydrophobic media. This project aims to solve an intractable problem in froth flotation. Bubbles will be replaced by permeable, hydrophobic media, minimising the viscous hydrodynamic resistance that limits ultrafine particle recovery. The project expects to generate new knowledge relating the efficacy of the novel media to its underlying physical structure, composition, geometry, and interfacial structure. Expected outcomes include a framework for developing alternative, highly permeable, hydrophobic media, and new high performance separation technologies. This is expected to benefit large scale, low-cost, ultrafast processing of particulate suspensions in mineral processing and waste water treatment.Read moreRead less
Surface characteristics and hydrodynamics in detachment of coarse particles. Froth flotation is widely used for separating coal and minerals from the gangue. The largest particles that can be floated in the industry are 10 times smaller than the particles that can be floated under quiescent conditions. This project aims to better understand and quantify the detachment of large particles from the bubble surface. It aims to develop innovative modelling and experimental approaches to examine the ef ....Surface characteristics and hydrodynamics in detachment of coarse particles. Froth flotation is widely used for separating coal and minerals from the gangue. The largest particles that can be floated in the industry are 10 times smaller than the particles that can be floated under quiescent conditions. This project aims to better understand and quantify the detachment of large particles from the bubble surface. It aims to develop innovative modelling and experimental approaches to examine the effect of particle surface characteristics and hydrodynamic conditions on coarse particle detachment and flotation. New ways to save energy by floating coarse composite particles are proposed to be developed. This research is at the forefront of flotation science and technology, and is expected to deliver significant outcomes to the mining industry.Read moreRead less
Maximising Bioenergy Recovery from Sewage Sludge. Sewage treatment is producing large amounts of sewage sludge, which represents a substantial, but largely untapped, energy source. This project aims to develop and demonstrate an innovative, economically attractive and environmentally friendly technology, and the underpinning science, to maximize bioenergy recovery from sewage sludge. The technology is based on the treatment of sludge using free ammonia, a by-product of sewage treatment. This pro ....Maximising Bioenergy Recovery from Sewage Sludge. Sewage treatment is producing large amounts of sewage sludge, which represents a substantial, but largely untapped, energy source. This project aims to develop and demonstrate an innovative, economically attractive and environmentally friendly technology, and the underpinning science, to maximize bioenergy recovery from sewage sludge. The technology is based on the treatment of sludge using free ammonia, a by-product of sewage treatment. This project is expected to benefit Australia by substantially reducing the reliance on fossil fuels and accelerating a shift to affordable renewable energy. The outcomes of the project would provide significant energy, economic, environmental and social benefits for Australians. Read moreRead less
A novel microbial process breaking through the nitrogen cycling. Nitrogen transformation is central to life on Earth. This project will challenge a century-old paradigm that microorganisms must cooperate in a team to convert nitrogen from organic- to inorganic forms. We will carry out the first-ever systematic investigation of a novel process, where a single organism mediates complete ammonification and ammonia oxidation, directly connecting organic- and inorganic nitrogen. By revealing metaboli ....A novel microbial process breaking through the nitrogen cycling. Nitrogen transformation is central to life on Earth. This project will challenge a century-old paradigm that microorganisms must cooperate in a team to convert nitrogen from organic- to inorganic forms. We will carry out the first-ever systematic investigation of a novel process, where a single organism mediates complete ammonification and ammonia oxidation, directly connecting organic- and inorganic nitrogen. By revealing metabolic pathways, characterising ecophysiological properties, isolating key microorganisms and exploring their application potential, this project will change our fundamental understanding of global nitrogen cycling, improve the sustainability of water management, and contribute to the circular economy transitionRead moreRead less
Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important v ....Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important variables and thus make the estimation more efficient. The methods will be extended to multivariate responses where account will taken be taken of the structure of the dependence between responses.Read moreRead less