Understanding the implications of pandemic delays for the end of life. The untold toll of Covid-19 is emerging in ‘avoidable deaths’ linked to late(r) diagnosis or treatment due to pandemic-related delay. How delays are experienced and felt across families and communities requires urgent attention. This project aims to understand the implications of pandemic delay for dying and bereavement, including the sociocultural factors that shape experiences of illness and care amid delay. The significanc ....Understanding the implications of pandemic delays for the end of life. The untold toll of Covid-19 is emerging in ‘avoidable deaths’ linked to late(r) diagnosis or treatment due to pandemic-related delay. How delays are experienced and felt across families and communities requires urgent attention. This project aims to understand the implications of pandemic delay for dying and bereavement, including the sociocultural factors that shape experiences of illness and care amid delay. The significance of this project lies in its innovative sociological approach; expected outcomes include the generation of new knowledge on needs at the end of life that move across contexts and settings. Benefits include provision of findings that will inform social and health policy and practice improvements to enable good deaths.Read moreRead less
Understanding communication about advance care planning across the lifespan. This project aims to understand how people communicate about advance care planning for children, adolescents, and adults. This project expects to generate new knowledge by using leading social scientific and linguistic methods to analyse real-world advance care planning conversations and documents. Expected outcomes include detailed knowledge about challenges people encounter in these conversations and how to manage the ....Understanding communication about advance care planning across the lifespan. This project aims to understand how people communicate about advance care planning for children, adolescents, and adults. This project expects to generate new knowledge by using leading social scientific and linguistic methods to analyse real-world advance care planning conversations and documents. Expected outcomes include detailed knowledge about challenges people encounter in these conversations and how to manage these challenges. Over 170,000 Australians die each year, most from serious illness. This project should provide significant benefits to future initiatives for enhancing communication about advance care planning, especially in relation to young Australians, older Australians, and Australians with disabilities.Read moreRead less
A longitudinal study exploring women's experiences following a prenatal diagnosis of fetal abnormality. In Australia four per cent of babies are born with a congenital abnormality, many of which are detected during pregnancy. Little is known about women's experiences of a diagnosis. The aim of this study is to explore women's experiences following the diagnosis of a fetal abnormality during pregnancy, in order to develop appropriate models of supportive care.
Novel hybrid silica membranes for desalination. This project aims to produce high flux, highly stable ceramic membranes for use in desalination. This will result in novel, low energy desalination processes, delivering potable water at a greatly reduced cost.
Central nervous system cytokines and morphine analgesia. Morphine remains the drug of choice for the management of moderate-to-severe pain, however its clinical effectiveness is compromised by the fact that morphine's analgesic (pain reducing) efficacy becomes less effective the more it is administered.. This project will examine how analgesic tolerance develops from a completely new approach: Namely, how stimulation of the immune system within the central nervous system is a crucial factor in t ....Central nervous system cytokines and morphine analgesia. Morphine remains the drug of choice for the management of moderate-to-severe pain, however its clinical effectiveness is compromised by the fact that morphine's analgesic (pain reducing) efficacy becomes less effective the more it is administered.. This project will examine how analgesic tolerance develops from a completely new approach: Namely, how stimulation of the immune system within the central nervous system is a crucial factor in the development of tolerance. Modulation of analgesia by the immune system has not been systematically studied and provides a potentially fertile ground for the development of new techniques in the management of clinical pain.Read moreRead less
Monitoring Desalination Membrane Fouling using Sodium Magnetic Resonance. Seawater desalination using membrane modules is critical technology for potable water access, however it faces significant challenges due to fouling. Sodium magnetic resonance techniques will be developed to non-invasively detect and image salt accumulation in these opaque membrane modules due to fouling. These data will first be used to improve our understanding of the unexplored interplay between fouling and detrimental ....Monitoring Desalination Membrane Fouling using Sodium Magnetic Resonance. Seawater desalination using membrane modules is critical technology for potable water access, however it faces significant challenges due to fouling. Sodium magnetic resonance techniques will be developed to non-invasively detect and image salt accumulation in these opaque membrane modules due to fouling. These data will first be used to improve our understanding of the unexplored interplay between fouling and detrimental salt accumulation in the modules (known as cake-enhanced concentration polarisation) and thus validate 3D simulations of this phenomenon. The ability to unambiguously detect salt accumulation in membrane modules will then be extrapolated to a non-invasive monitoring tool for membrane fouling in desalination facilities.Read moreRead less
Novel disinfection to combat antibiotic resistance . Control of antimicrobial resistance in water is critical. Disinfection in water and wastewater treatment plants is a vital barrier against antibiotic resistant bacteria (ARB); however, it is less effective in controlling- and may even facilitate the spread of antibiotic resistance genes (ARGs). This project aims to comprehensively investigate the effectiveness of widely-used disinfection processes in controlling ARB/ARGs, determine the underly ....Novel disinfection to combat antibiotic resistance . Control of antimicrobial resistance in water is critical. Disinfection in water and wastewater treatment plants is a vital barrier against antibiotic resistant bacteria (ARB); however, it is less effective in controlling- and may even facilitate the spread of antibiotic resistance genes (ARGs). This project aims to comprehensively investigate the effectiveness of widely-used disinfection processes in controlling ARB/ARGs, determine the underlying mechanisms, and identify optimal treatment conditions. This project also aims to develop a novel, cost-effective and environmentally friendly disinfection process for efficient ARGs destruction, thus significantly strengthening Australia’s capacity to prevent the spread of antibiotic resistance.Read moreRead less
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
All-solid-state Z-scheme photocatalysts for water treatment. The project aims to develop high-performance Z-scheme photocatalysts by using two-dimensional (2D) semiconductors as building blocks for low-cost, highly-efficient pathogen inactivation and emerging pollutant degradation in stormwater treatment. The project expects to generate new fundamental knowledge in the area of photocatalyst design and Z-scheme photocatalytic system, and advance the application of photocatalytic oxidation in wate ....All-solid-state Z-scheme photocatalysts for water treatment. The project aims to develop high-performance Z-scheme photocatalysts by using two-dimensional (2D) semiconductors as building blocks for low-cost, highly-efficient pathogen inactivation and emerging pollutant degradation in stormwater treatment. The project expects to generate new fundamental knowledge in the area of photocatalyst design and Z-scheme photocatalytic system, and advance the application of photocatalytic oxidation in water treatment. The expected outcomes of the project include novel 2D Z-scheme photocatalysts and enhanced capacity in stormwater management.Read moreRead less
Molecular Cell Biology and Comparative Genomics Of Planctomycetes and Verrucomicrobia In Relation To Evolution Of Cytoskeletal Proteins and Membrane-bounded Compartments. Planctomycetes and verrucomicrobia are evolutionarily distinct groups of bacteria which possess unusual cell structure and which share some significant genes important in cell biology with eukaryotes e.g. in verrucomicrobia the cytoskeleton protein tubulin. These bacteria are important for understanding the transition from no ....Molecular Cell Biology and Comparative Genomics Of Planctomycetes and Verrucomicrobia In Relation To Evolution Of Cytoskeletal Proteins and Membrane-bounded Compartments. Planctomycetes and verrucomicrobia are evolutionarily distinct groups of bacteria which possess unusual cell structure and which share some significant genes important in cell biology with eukaryotes e.g. in verrucomicrobia the cytoskeleton protein tubulin. These bacteria are important for understanding the transition from non-nucleated cells with simple cell division to nucleated cells with chromosome separation via cytoskeletal protein movement.The project will compare genomes of of planctomycetes and verrucomicrobia to determine their relationship, determine whether the tubulin homolog of verrucomicrobia can form cytoskeleton structures, and characterize the cytoskeleton of ammonium-oxidizing planctomycetes used in wastewater treatment.Read moreRead less