The identification of Mycosphaerella graminicola effectors that promote pathogenicity on wheat. Fungal diseases are one of the greatest challenges to sustainable wheat production in the 21st century. Septoria tritici blotch is one such disease as it inflicts millions of tonnes in yield losses per annum. This project will identify the molecular basis of Septoria tritici blotch and assess its potential as an Australian biosecurity threat.
Evolving with sexually transmitted infections. This project aims to understand how sexually transmitted infections (STIs) affect the evolution of host mating systems. STIs threaten the health of most sexually-reproducing organisms. In evolutionary terms, their mode of transmission imposes distinct selection patterns on hosts. This project will use an Australian beetle and its sexually transmitted mite to investigate how STIs lead to evolutionary changes in host mating behaviour and explore the g ....Evolving with sexually transmitted infections. This project aims to understand how sexually transmitted infections (STIs) affect the evolution of host mating systems. STIs threaten the health of most sexually-reproducing organisms. In evolutionary terms, their mode of transmission imposes distinct selection patterns on hosts. This project will use an Australian beetle and its sexually transmitted mite to investigate how STIs lead to evolutionary changes in host mating behaviour and explore the genetic basis for STI resistance. This project is expected to affect the evolution of host mating biology and lead to sex-specific optimal levels of disease resistance, which can influence disease dynamics and host-disease coevolution.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100068
Funder
Australian Research Council
Funding Amount
$931,950.00
Summary
Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under ....Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under environmental stress; integral chemical signals exchanged in host-microbe interactions; and volatile signatures linked to ecosystem health and developmental anomalies in animals. Results will inform innovative strategies to enhance biological adaptation, climate resilience and plant, animal, and ecosystem health.Read moreRead less
Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new tec ....Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new techniques for acquisition of DNA from museum specimens. The project is expected to provide significant benefits, such as insights into the processes that promote new species in nature.Read moreRead less
Evolved enzymes and biomimetics for organophosphate degradation. Organophosphate (OP) pesticides are an indispensable part of modern agriculture - their use results in dramatically increased crop yields. However, they are toxic and can damage the environment and cause significant health problems. This project intends to evolve enzymes capable of dealing with problems caused by OPs.
Tracking flood waters over Australia using space gravity data. This project aims to assess the utility of near-real-time data from the currently operating space gravity satellite mission to quantify and track flood waters in Australia. Through analysis of the satellite data and fusion of observed signals with rainfall, river flows and conventional hydrological modelling, it expects to create new knowledge of soil moisture and movement of flood waters. Expected outcomes include a capability to im ....Tracking flood waters over Australia using space gravity data. This project aims to assess the utility of near-real-time data from the currently operating space gravity satellite mission to quantify and track flood waters in Australia. Through analysis of the satellite data and fusion of observed signals with rainfall, river flows and conventional hydrological modelling, it expects to create new knowledge of soil moisture and movement of flood waters. Expected outcomes include a capability to improve hydrological models by including the information of water signals obtained from the near-real-time observations. This should provide significant benefits such as more accurate land saturation maps and better predictions of runoff and flood risk.Read moreRead less
Evolutionary origins of sexual parasitism in an Australian freshwater fish. Carp gudgeons are the most abundant, widespread and biodiverse freshwater fishes in southeastern Australia. The unacknowledged presence of many cryptic species and sexually-parasitic lineages severely taints all research on this cornerstone group. This project aims to provide unrivalled evolutionary, genomic, and taxonomic insights into this new instance of vertebrate sexual parasitism, which offers a unique mix of resea ....Evolutionary origins of sexual parasitism in an Australian freshwater fish. Carp gudgeons are the most abundant, widespread and biodiverse freshwater fishes in southeastern Australia. The unacknowledged presence of many cryptic species and sexually-parasitic lineages severely taints all research on this cornerstone group. This project aims to provide unrivalled evolutionary, genomic, and taxonomic insights into this new instance of vertebrate sexual parasitism, which offers a unique mix of research advantages not displayed by any other sexual/unisexual complex. The knowledge gained could impact many research fields, including evolutionary theory addressing the unexplainable prevalence of sex, native fish ecology, and environmental monitoring of the Murray-Darling Basin, an ecosystem of world significance.Read moreRead less
Restoring amphibian populations in chytrid-impacted landscapes. This project aims to address an outstanding problem in wildlife disease ecology: how can we enable susceptible amphibians to persist in the face of the chytrid pathogen, which has devastated amphibian biodiversity? This project expects to generate new knowledge by experimentally trialling two highly promising interventions: immunising animals and creating disease refugia through simple habitat manipulations. Outcomes of this project ....Restoring amphibian populations in chytrid-impacted landscapes. This project aims to address an outstanding problem in wildlife disease ecology: how can we enable susceptible amphibians to persist in the face of the chytrid pathogen, which has devastated amphibian biodiversity? This project expects to generate new knowledge by experimentally trialling two highly promising interventions: immunising animals and creating disease refugia through simple habitat manipulations. Outcomes of this project include a framework for predicting how interventions might enable host-pathogen coexistence. This project should provide significant benefits including enhanced understanding of wildlife disease dynamics that will pave the way for interventions to restore amphibian biodiversity in chytrid-impacted landscapes.Read moreRead less
Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites ....Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites to survive in the new host. Anticipated outcomes include the identification of new intervention strategies and improved transmission model systems for vector-borne diseases. This gained knowledge could provide benefits to future biomedical applications by informing diagnostics or treatment of lipid associated diseases.Read moreRead less
What drives parasite spread through social networks: lessons from lizards. Australia's biodiversity is continually threatened by new epidemics of local and foreign diseases and parasites. This project will enhance our understanding of how these diseases spread, allowing more effective controls to be developed to protect wildlife species, animal populations and, ultimately, Australian ecosystems.