Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia ....Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia from invasive diseases. There is an urgency to undertake our research because global environmental change and increasing movements of people (particularly military personnel) from overseas regions where these diseases are endemic is increasing the vulnerability of northern Australia to the (re)establishment of mosquito borne diseases.Read moreRead less
Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100219
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate k ....A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate key questions in oceanography and the mining and energy, archaeological, agricultural, and forestry sectors. The facility is expected to substantially increase expertise and training in radionuclides in Australia, and promote high-level research collaborations and outputs of both national and international significance. Major outcomes of the proposed facility include better understanding of how oceans regulate climate and improved capacity to assess effects of radiation on natural ecosystems.Read moreRead less
The republic of the demiurge: textual community and the commentary tradition in late antique Platonism. This project will add to our understanding of the content and purpose of philosophy within 'higher education' in the eastern Roman Empire in the period 300-500 CE. Since there are many ways in which the late Empire resembles our own time, this understanding illuminates the place of philosophy in what we call higher education.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100009
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
Magnetometry Facility for Molecular and Nanoscale Materials. Advances in information and communications technology are critically dependent on increasing the capacity, speed and energy efficiency of logic and memory electronic devices. These improvements can be achieved by reducing component size to the nanoscale and using magnetic spin as well as charge. This Project aims to establish Australia's first integrated Magnetometry Facility for determining the magnetic properties of a range of nanosc ....Magnetometry Facility for Molecular and Nanoscale Materials. Advances in information and communications technology are critically dependent on increasing the capacity, speed and energy efficiency of logic and memory electronic devices. These improvements can be achieved by reducing component size to the nanoscale and using magnetic spin as well as charge. This Project aims to establish Australia's first integrated Magnetometry Facility for determining the magnetic properties of a range of nanoscale materials down to the level of individual nanomagnets. The Facility will provide crucial characterisation capabilities for Australian researchers, building capacity to develop new magnetic nanomaterials and devices for high-density data storage, quantum computing and spintronics.
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The recovery of seagrass beds: the role of catchments and options for management responses. Seagrass beds once dominated tidal flats but are disappearing at an increasing rate due to human actions, both in Australia and around the world. This project will develop an understanding of the processes that cause these losses, the factors that prevent seagrass-bed re-establishment, and provide a framework for evaluating alternative management options.
Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisati ....Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisations. The research will utilise an innovative mixed-methods approach to investigate and to analyse the strategies and experiments of adaptation practices. It aims to develop new ways of identifying and implementing practical, local, adaptive responses that are contextually relevant, socially innovative and capacity building.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100029
Funder
Australian Research Council
Funding Amount
$280,000.00
Summary
Ultra-trace analytical facility for earth system change . A new cutting-edge research capability will be established to safe guard Australia's natural resources and environment and to determine past variability in climate. Research results from the facility will help to guide national and international policy makers with regards to sustainable development and management of resources.