Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic erro ....Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic errors affecting thousands. This research tests a new method of assessing diagnostic skills based on how skilled operators respond to cues. This project will test how employees’ diagnostic skills change and whether this change corresponds to measures of organisational performance. This research is expected to provide organisations with a tool to pre-empt diagnostic errors that could minimise costs to the economy.Read moreRead less
Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maint ....Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maintain psychosocial wellbeing. This project expects to generate new knowledge in recruiting, retaining, and deferring older blood donors. Expected outcomes include tailored, validated resources that may significantly benefit Australia by effectively engaging older adults to ensure the sustainability of the blood supply.Read moreRead less
Designing Human Resource Practices that Promote the Retention of Volunteers. This project aims to examine the effects of human resources practices on the attraction and retention of high-quality volunteers. Volunteers provide essential health and educational services to the Australian population, which makes it important for non-profit organisations to develop effective human resource practices that attract and retain the best people. However, non-profit organisations often struggle to attract a ....Designing Human Resource Practices that Promote the Retention of Volunteers. This project aims to examine the effects of human resources practices on the attraction and retention of high-quality volunteers. Volunteers provide essential health and educational services to the Australian population, which makes it important for non-profit organisations to develop effective human resource practices that attract and retain the best people. However, non-profit organisations often struggle to attract and retain a sufficient number of volunteers. This project will examine the effects of three human resource practices on the thriving and organisational attachment of volunteers using theories of motivation and retention. This knowledge is intended to help governments and non-profit organisations improve on policies and procedures to manage Australia’s volunteer workforce sustainably.Read moreRead less
The Future In Our Hands: Screening For Preclinical Alzheimer's Disease By Analysing Hand Movements
Funder
National Health and Medical Research Council
Funding Amount
$899,782.00
Summary
Alzheimer's disease (AD) starts damaging the brain 10-20 years before memory problems begin. By the time of diagnosis, it is hard to treat because the damage is so severe. We need a way to detect AD much earlier. We will develop a simple new computer test to detect early signs of AD by recording and analysing hand movements. Then people can start prevention earlier and scientists can research better treatments to improve people's quality of life and reduce the number of people with dementia.
Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
The Role Of Excitotoxicity In Mediating Distal Axonal Degneration In ALS
Funder
National Health and Medical Research Council
Funding Amount
$392,952.00
Summary
Amyotrophic lateral sclerosis (ALS), the major cause of motor neuron disease, is a devastating diseasse for which there is no cure. There have been significant advances in understanding the pathology of ALS yet we still don’t know what causes the dying back of spinal motor neurons. We have new evidence that suggests that ALS may, in part, be caused by excitotoxcity - or over stimulation - of neurons in the spinal cord. We will follow this lead using a range of cutting edge experimental models.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
From risk factor analysis to translation: multiple sclerosis and vitamin D deficiency. This research on multiple sclerosis will focus on its causes and lifestyle factors that affect it and will trial vitamin D supplementation as a treatment. Studies on vitamin D deficiency in healthy populations aim to develop new public health recommendations on sun exposure and vitamin D that balance risk of skin cancer against vitamin D deficiency.