Modelling of Nitric Oxides and Carbon Monoxide Emissions from Bagasse-Fires Boilers. The project aims to develop computational models to predict emissions of nitric oxides and carbon monoxide from sugar-mill boilers burning bagasse. Bagasse combustion does not contribute to greenhouse gas emissions and clean and efficient combustion of this fuel has become very important for the sugar industry and for Australia. The project combines the opportunity of direct boiler measurements by SRI with the m ....Modelling of Nitric Oxides and Carbon Monoxide Emissions from Bagasse-Fires Boilers. The project aims to develop computational models to predict emissions of nitric oxides and carbon monoxide from sugar-mill boilers burning bagasse. Bagasse combustion does not contribute to greenhouse gas emissions and clean and efficient combustion of this fuel has become very important for the sugar industry and for Australia. The project combines the opportunity of direct boiler measurements by SRI with the modelling expertise at the University to develop combustion-kinetics models for these species. The models will be incorporated into the previously developed computational fluid dynamics - combustion code of the furnace to give the capability of emission prediction as a function of burner operating conditions and fuel parameters.Read moreRead less
Innovative strategy for salt management and water recovery from newsprint mill effluent using membrane processes. Newsprint mills are a major employer in regional Australia. The mills are located in environmentally sensitive areas, consume large quantities of water and return high levels of salt to the environment. To remain competitive the newsprint industry, like all industries in regional Australia must develop new strategies for water recycling and salt management. Successful execution of t ....Innovative strategy for salt management and water recovery from newsprint mill effluent using membrane processes. Newsprint mills are a major employer in regional Australia. The mills are located in environmentally sensitive areas, consume large quantities of water and return high levels of salt to the environment. To remain competitive the newsprint industry, like all industries in regional Australia must develop new strategies for water recycling and salt management. Successful execution of this project will minimize water consumption in newsprint production, mitigate the effects of increased sodicity in soils irrigated with mill effluent and accelerate the commercial development a hydrophobic microporous membrane for water recycling and salt removal in environmentally sensitive areas of inland Australia.Read moreRead less
The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (th ....The Development of New Carrier Technologies for Spray-Dried Fruit Extracts. This project aims to develop new carrier techniques for spray drying fruit extracts based on the use of natural fibres, with the aim of overcoming a key problem in the operation of spray dryers for producing powders, the deposition of particles on walls. Carriers are non-sticky materials that effectively dilute the stickiness of any materials. The significance is that it will use waste products from fruit processing (the fibres from skins) to overcome this problem, and it will also be possible to dry sticky materials using material from the fruit itself, rather than additives such as maltodextrin.Read moreRead less
A skin-on-a-chip device for investigating wound healing. This project aims to research the mechanism of skin wound healing. It will design a skin-on-a-chip microfluidic device that mimics human skin in vitro. This device will reduce the need for animal studies and assess how active compounds heal wounds. This project will design smart polymers with superior properties for controlled delivery of multiple active compounds in this device and choose the most effective combination of compounds to boo ....A skin-on-a-chip device for investigating wound healing. This project aims to research the mechanism of skin wound healing. It will design a skin-on-a-chip microfluidic device that mimics human skin in vitro. This device will reduce the need for animal studies and assess how active compounds heal wounds. This project will design smart polymers with superior properties for controlled delivery of multiple active compounds in this device and choose the most effective combination of compounds to boost skin healing rate. This knowledge may ultimately be used to develop wound dressings that maximise healing rate for various skin defects such as chronic wounds and decrease health care costs.Read moreRead less
Defining Fundamental Principles for the Design and Operation of Membrane Systems from Time-Varying Performance Analysis. To date, much of the process improvement for industrial application of membrane technology has revolved around polymer science based development of membrane materials and process and module changes resulting from the application of basic (often simplistic) engineering principles. While some future improvements may still come from these areas, the most dramatic advances are li ....Defining Fundamental Principles for the Design and Operation of Membrane Systems from Time-Varying Performance Analysis. To date, much of the process improvement for industrial application of membrane technology has revolved around polymer science based development of membrane materials and process and module changes resulting from the application of basic (often simplistic) engineering principles. While some future improvements may still come from these areas, the most dramatic advances are likely to be derived from the application of advanced engineering principles to this complex system. This project will integrate advanced CFD modelling and control principles for the design and operation of membrane systems in order to develop fundamental understanding that should lead to significant process improvements.Read moreRead less
Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of ....Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of new methods to optimise particle deposition, development of tunable powder formulations, as well as definition of particle-surface interaction mechanisms in flows. The project should provide significant benefits to particle systems for applications ranging from additive manufacturing to aerosol delivery.Read moreRead less
Discrete particle simulation of powder dispersion in pharmaceutical aerosol inhalers. A successful completion of the project will i) greatly enhance the Australian R&D profile and capabilities of both computational modelling and pharmaceutical aerosol research in the world; ii) provide an improved delivery of therapeutic dose to patients via inhalers with better performance to enhance the therapeutic benefits; iii) enable wide availability of inexpensive and effective pharmaceutical inhalation p ....Discrete particle simulation of powder dispersion in pharmaceutical aerosol inhalers. A successful completion of the project will i) greatly enhance the Australian R&D profile and capabilities of both computational modelling and pharmaceutical aerosol research in the world; ii) provide an improved delivery of therapeutic dose to patients via inhalers with better performance to enhance the therapeutic benefits; iii) enable wide availability of inexpensive and effective pharmaceutical inhalation products to the Australian community for the treatment of asthma and other diseases, iv) facilitate environmentally friendly technology since powder aerosol delivery does not require any harmful organic solvents to operate.Read moreRead less
Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol a ....Synthesis of nanoparticles by impinging liquid-jet precipitation for inhalation drug delivery. The project aim is to develop a state of the art technology for the efficient, reliable and economical production of nanoparticles of drugs suitable for inhalation delivery to the lung. Nanoparticles can penetrate deeper into the lung where they deposit and dissolve faster for enhanced therapeutic effects. The project will focus on both the production process and the particle properties for aerosol administration. Successful development of the technology will not only gain new knowledge in the key area of nanotechnology, but also lead to better inhalation therapy to benefit patients.Read moreRead less
Developing novel aerosol inhalers for pulmonary drug delivery from the fundamental understanding of powder dispersion mechanisms. The project seeks to understand how powder aerosol inhalers can be significantly improved. The outcome will provide therapeutic benefits to the Australian community for better treatment of respiratory diseases and facilitate environmentally friendly technology since these inhalers do not require any harmful organic solvents to operate.
Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung inf ....Development of a novel process for the formation of particles with controlled surface architecture for respiratory drug delivery. A successful conclusion of this project will enhance substantially the competitiveness of Australia's research in functional nanomaterials and advanced biomaterials. The Australian pharmaceutical industry will gain through the ability to develop proprietary pharmaceutical formulations targeted towards taking advantage of the novel process. Patients of asthma, lung infection and other serious health problems will benefit from an improved delivery of therapeutic dose at a much reduced cost. The technology is environmentally friendly as powder aerosol delivery does not require any harmful organic solvent to operate.Read moreRead less