Post-market Surveillance Of Medicine-related Adverse Events
Funder
National Health and Medical Research Council
Funding Amount
$99,248.00
Summary
Observational studies using administrative data are an important complement to spontaneous reporting systems for detecting medicine-related adverse events after they go to market, as they reflect real-world use of medicines; yet, they require rigorous methodological approaches to avoid bias. This project will review the existing methodologies for detecting adverse events in administrative data and apply them to Australian data.
Statistical Approaches For Studying The Safety And Effectiveness Of Medicines
Funder
National Health and Medical Research Council
Funding Amount
$307,946.00
Summary
When medicines first reach the market many of the potential adverse reactions are unknown. Clinical trials of medicines often exclude elderly patients and patients with multiple chronic diseases who are at higher risk of adverse drug reactions. This research aims to improve medicine safety by developing statistical methods to detect and validate medication safety signals and to identify patients who are at high risk of adverse reactions to medicines.