Star Formation at Millimetre Wavelengths with the CSIRO Australia Telescope. The newly-upgraded CSIRO Australia Telescope Compact Array, together with the CSIRO Mopra Telescope, provide a unique and powerful combination for studying the millimetre-wave emission from molecules and cold dust in star formation regions. We propose to combine the astrophysical expertise of UNSW with the instrumental expertise of CSIRO to use these instruments to study the processes of star formation. There are two pa ....Star Formation at Millimetre Wavelengths with the CSIRO Australia Telescope. The newly-upgraded CSIRO Australia Telescope Compact Array, together with the CSIRO Mopra Telescope, provide a unique and powerful combination for studying the millimetre-wave emission from molecules and cold dust in star formation regions. We propose to combine the astrophysical expertise of UNSW with the instrumental expertise of CSIRO to use these instruments to study the processes of star formation. There are two parallel themes to this research: to commission and develop optimal techniques for using the new instruments, and to make use of them to explore the poorly-understood processes that cause stars to form.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347403
Funder
Australian Research Council
Funding Amount
$222,000.00
Summary
An ultra-wideband digital filterbank for the Mopra Radiotelescope. We seek funding to equip the Mopra radiotelescope with an ultra-wide-bandwidth digital filter bank. This will greatly improve the efficiency of the observatory, increasing the speed at which spectroscopic data is acquired by a factor of 8, and the speed of acquiring continuum data by a factor of 32. Once equipped in this way, Mopra, which is already the largest millimetre-wave radiotelescope in the southern hemisphere, will enjo ....An ultra-wideband digital filterbank for the Mopra Radiotelescope. We seek funding to equip the Mopra radiotelescope with an ultra-wide-bandwidth digital filter bank. This will greatly improve the efficiency of the observatory, increasing the speed at which spectroscopic data is acquired by a factor of 8, and the speed of acquiring continuum data by a factor of 32. Once equipped in this way, Mopra, which is already the largest millimetre-wave radiotelescope in the southern hemisphere, will enjoy an unbeatable edge over all other competing observatories around the world through its combination of collecting area and bandpass.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775523
Funder
Australian Research Council
Funding Amount
$223,000.00
Summary
A new field plate for the 6DF multi-object spectroscopy system on the Anglo-Australian Observatory's Schmidt telescope. Astronomy engages the public like no other science. This flagship project is Australian based, uses Australian technology and although international has a strong Australian flavour in scientific leadership and participation. The experiment will yield a massive leap forward in our understanding of our Milky Way Galaxy. Australia 'punches above its weight' in astronomy because ....A new field plate for the 6DF multi-object spectroscopy system on the Anglo-Australian Observatory's Schmidt telescope. Astronomy engages the public like no other science. This flagship project is Australian based, uses Australian technology and although international has a strong Australian flavour in scientific leadership and participation. The experiment will yield a massive leap forward in our understanding of our Milky Way Galaxy. Australia 'punches above its weight' in astronomy because of our innovation, ability to maximise limited resources and to cannily target projects with high return for the investment applied. The same rationale here is delivering excellent science. To secure this return into the second, most productive phase requires modest additional investment by Australia and our partners in the necessary project infrastructure.Read moreRead less
Pulsed oscillating mass analyser. Mass spectrometers are ubiquitous components in chemical analysis, but are often large and expensive. We have developed a new method for mass analysis, which is smaller and cheaper than existing technology. However, the analyser needs further research to determine whether it has the performance specifications to match the other technologies. The objective of this research is to characterise, explore and extend the prototype and to develop the appropriate math ....Pulsed oscillating mass analyser. Mass spectrometers are ubiquitous components in chemical analysis, but are often large and expensive. We have developed a new method for mass analysis, which is smaller and cheaper than existing technology. However, the analyser needs further research to determine whether it has the performance specifications to match the other technologies. The objective of this research is to characterise, explore and extend the prototype and to develop the appropriate mathematical algorithm for mass analysis. Success in this project may lead to a new mass analyser that can be incorporated into analytical instruments, many of which are manufactured in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560672
Funder
Australian Research Council
Funding Amount
$202,705.00
Summary
Ultrafast laser facility for chemical, biological and physical investigations of advanced materials. Ultrafast laser techniques are becoming indispensable in many diverse scientific disciplines. Within the Australian scientific community, there is a great need for enhanced access to sophisticated ultrafast laser instrumentation. The expansion to the femtosecond laser facility through the addition of state-of-the-art laser devices, will enable novel laser spectroscopy measurements and advanced op ....Ultrafast laser facility for chemical, biological and physical investigations of advanced materials. Ultrafast laser techniques are becoming indispensable in many diverse scientific disciplines. Within the Australian scientific community, there is a great need for enhanced access to sophisticated ultrafast laser instrumentation. The expansion to the femtosecond laser facility through the addition of state-of-the-art laser devices, will enable novel laser spectroscopy measurements and advanced optical microscopy techniques to be applied to investigations of advanced materials and biological systems. Access to such instrumentation is crucial to fields including photoluminescent conductive polymers, nanoparticles, engineered supramolecules for artificial photosynthetic systems, and photoactivated therapy and drug delivery/release technology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883030
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
High-Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at the Nanometre-Level. The Field Emission Scanning Electron Microscope (FESEM) is designed to provide fundamental insights into physical and biological systems though characterisation and analysis of structures on nanometre length scales. This versatile instrument will support a wide range of research projects covering all four national research priorities. These range from the characterisation of ....High-Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at the Nanometre-Level. The Field Emission Scanning Electron Microscope (FESEM) is designed to provide fundamental insights into physical and biological systems though characterisation and analysis of structures on nanometre length scales. This versatile instrument will support a wide range of research projects covering all four national research priorities. These range from the characterisation of light alloys to boost and intensify Australia's aluminium, magnesium and titanium alloy industries, to tissue engineering for the repair of human elastic tissues in skin, artery, bladder and lung, to the study of microtubules in plant cells for genetic manipulation of plants to withstand environmental stresses such as drought or salinity.Read moreRead less
Astrophotonics: exploiting a new technological frontier to probe back to the Dark Ages. Photonics, a key research strength in Australia, emerged from the telecommunications industry. But this exciting field has now begun to foster new scientific disciplines. One of the most recent is astrophotonics, a field at the interface of photonics and another Australian research strength, astronomy. Astrophotonics will deliver cutting-edge technologies to ensure Australia's astronomical lead in the next de ....Astrophotonics: exploiting a new technological frontier to probe back to the Dark Ages. Photonics, a key research strength in Australia, emerged from the telecommunications industry. But this exciting field has now begun to foster new scientific disciplines. One of the most recent is astrophotonics, a field at the interface of photonics and another Australian research strength, astronomy. Astrophotonics will deliver cutting-edge technologies to ensure Australia's astronomical lead in the next decade. These new facilities will serve as a vital stepping stone to the Giant Magellan Telescope, a $500M project promising enormous economic, engineering and scientific opportunities for Australia. Astrophotonics will also lead to innovative technology transfer to fields such as medical science, optical computing and sensor technology.Read moreRead less
Electro-active and migratory peptides in lipid bilayers: NMR and biophysical studies. All living things are characterized by the separation of inner space from the surrounding medium by a self-assembling membrane. Selective entry and exit of water, ions and solutes is a defining feature of each type of cell. Some proteins sense the voltage difference across the cell membrane and open or close in response to voltage changes. Others, like bacterial toxins assemble in the membrane as pores, while o ....Electro-active and migratory peptides in lipid bilayers: NMR and biophysical studies. All living things are characterized by the separation of inner space from the surrounding medium by a self-assembling membrane. Selective entry and exit of water, ions and solutes is a defining feature of each type of cell. Some proteins sense the voltage difference across the cell membrane and open or close in response to voltage changes. Others, like bacterial toxins assemble in the membrane as pores, while other peptides migrate across the membrane piggy-backing their peptide cargo. The aim is to understand the molecular mechanisms in examples of these membrane-active peptides and proteins with a view to enabling rational intervention into their operation in situ in normal and disease states.Read moreRead less
NMR studies of membrane proteins and peptides in novel amphiphilic mesophases. Membrane proteins are the next frontier in structural biology. Our goal is the structural and mechanistic characterization of the proteins and peptides from platypus venom and a cardiac potassium ion channel, HERG, that has a particular role in the suppression of cardiac arrhythmias. To do this we will refine and develop methods using amphiphilic mesophases and micelles and state-of-the-art NMR spectroscopy. Electrop ....NMR studies of membrane proteins and peptides in novel amphiphilic mesophases. Membrane proteins are the next frontier in structural biology. Our goal is the structural and mechanistic characterization of the proteins and peptides from platypus venom and a cardiac potassium ion channel, HERG, that has a particular role in the suppression of cardiac arrhythmias. To do this we will refine and develop methods using amphiphilic mesophases and micelles and state-of-the-art NMR spectroscopy. Electrophysiological analysis of ion channels and interactions with toxins will relate NMR structures to function. The NMR methodologies we develop will have broad applicability to membrane proteins in general.
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Protein chips for the high-throughput study of immune complexes by mass spectrometry. Mass spectrometry is a core enabling technology for proteomics with proteins identified by molecular weight, mass maps and sequencing within the confines of a mass spectrometer. We have found conditions under which it is possible to preserve and detect protein complexes by matrix-assisted laser desorption ionization (MALDI) mass spectrometry that has promising implications for the high-throughput screening of p ....Protein chips for the high-throughput study of immune complexes by mass spectrometry. Mass spectrometry is a core enabling technology for proteomics with proteins identified by molecular weight, mass maps and sequencing within the confines of a mass spectrometer. We have found conditions under which it is possible to preserve and detect protein complexes by matrix-assisted laser desorption ionization (MALDI) mass spectrometry that has promising implications for the high-throughput screening of protein-protein interactions. Technologies pioneered by the applicant will be advanced to achieve the high-throughput analysis of antibody complexes with native gel recovered protein antigens across emerging strains of the influenza virus by means of miniature protein chips.Read moreRead less