Reliable and accurate statistical solutions for modern complex data. This project aims to develop novel methods for reliable and accurate statistical modelling with modern, complex correlated and error-prone data. The project expects to make significant strides towards future-proofing statistical data analysis, equipping practitioners with a suite of robust and computationally efficient methods which provide confidence in the stability and reproducibility of results obtained, while offering guar ....Reliable and accurate statistical solutions for modern complex data. This project aims to develop novel methods for reliable and accurate statistical modelling with modern, complex correlated and error-prone data. The project expects to make significant strides towards future-proofing statistical data analysis, equipping practitioners with a suite of robust and computationally efficient methods which provide confidence in the stability and reproducibility of results obtained, while offering guarantees on their transferability over a range of populations. This will provide important benefits as they are applied in predicting endangered marine species for fisheries conservation, and in enhancing our national understanding of the relationship between education achievement and financial success. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100004
Funder
Australian Research Council
Funding Amount
$762,800.00
Summary
Ultrafast Infrared Spectroscopy Facility. The Ultrafast Infrared Spectroscopy Facility will provide a suite of techniques spanning the visible to mid-infrared spectral regions, on time scales corresponding to the emission of light, and energy conversion in low energy advanced functional materials. Research performed with this equipment will include photonic and thermal energy conversion; nanophotonics; quantum technologies and new infrared functional materials. This facility will enhance capacit ....Ultrafast Infrared Spectroscopy Facility. The Ultrafast Infrared Spectroscopy Facility will provide a suite of techniques spanning the visible to mid-infrared spectral regions, on time scales corresponding to the emission of light, and energy conversion in low energy advanced functional materials. Research performed with this equipment will include photonic and thermal energy conversion; nanophotonics; quantum technologies and new infrared functional materials. This facility will enhance capacity in probing new materials and devices in the near and mid-infrared regions, and will increase institutional and cross-disciplinary research collaboration.Read moreRead less
Force-from-lipids biophysical principle underlying mechanotransduction. The major aim of this project is to determine evolutionary conserved physical principles of mechanotransduction in living cells through structure and function studies of PIEZO mechanoreceptor channels playing a crucial role in senses such as touch and pain in animals and humans. Mutations in these channels can cause numerous genetic disorders, including hereditary anaemias and joint contractures. Since they have been shown t ....Force-from-lipids biophysical principle underlying mechanotransduction. The major aim of this project is to determine evolutionary conserved physical principles of mechanotransduction in living cells through structure and function studies of PIEZO mechanoreceptor channels playing a crucial role in senses such as touch and pain in animals and humans. Mutations in these channels can cause numerous genetic disorders, including hereditary anaemias and joint contractures. Since they have been shown to respond to mechanical stimuli in the same manner as mechanoreceptor channels of organisms from bacteria to humans the intended outcome of this project is to uncover the unifying principles of mechanotransduction anchored in the laws of physics and chemistry that have guided the force-dependent design of all life forms.Read moreRead less
A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of import ....A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of important organic reactions and enhancing collaboration nationally and internationally between computational and synthetic chemists. This should provide significant benefits in the form of improved chemical reactions for chemists to prepare new pharmaceuticals, agrochemicals and materials.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Determining fossilisation processes of a rare iron-rich Lagerstätte. Most fossil sites only preserve resistant elements such as bones and teeth, leading to questions about how soft animals and structures have evolved over time. The recent discovery of a fossil deposit in New South Wales appears to demonstrate a new set of conditions for the preservation of soft tissues. This project aims to constrain the age of and assess the fossilisation processes that produced this unique fossil site. We will ....Determining fossilisation processes of a rare iron-rich Lagerstätte. Most fossil sites only preserve resistant elements such as bones and teeth, leading to questions about how soft animals and structures have evolved over time. The recent discovery of a fossil deposit in New South Wales appears to demonstrate a new set of conditions for the preservation of soft tissues. This project aims to constrain the age of and assess the fossilisation processes that produced this unique fossil site. We will use an integrative approach to reconstruct the formation of this Lagerstätte. The work will provide significant advances in our understanding of the process of fossilisation and guide the discovery of other exceptionally-well preserved fossil deposits, critical in reconstructing the biological history of Australia.Read moreRead less
Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilit ....Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilities, and released for community use. These developments underpin future ocean state forecasts, sea ice forecasts, wave forecasts, decadal climate prediction and climate process studies. The project will benefit search and rescue, Defence and shipping operations, and will enhance future climate projections.Read moreRead less
Deciphering ion specificity in complex electrolytes . This project aims to understand how ions influence the behaviour and properties of complex electrolytes (solutions containing either multiple ions, solvent mixtures, high electrolyte concentrations or a variety of interfaces, solutes or polymers). Complex electrolytes are ubiquitous in colloidal and particle technologies and underpin industrial and natural processes. Our team will combine experiment, simulation and theory to deliver a univers ....Deciphering ion specificity in complex electrolytes . This project aims to understand how ions influence the behaviour and properties of complex electrolytes (solutions containing either multiple ions, solvent mixtures, high electrolyte concentrations or a variety of interfaces, solutes or polymers). Complex electrolytes are ubiquitous in colloidal and particle technologies and underpin industrial and natural processes. Our team will combine experiment, simulation and theory to deliver a universal framework for understanding and predicting specific ion effects in complex electrolytes. The project outcomes are expected to deliver new understanding for researchers, robust rules of thumb for technologists and a public resource for data-driven solutions in applications utilising salt solutions. Read moreRead less
Unravelling the dominant drivers of ion specificity. This project aims to understand what governs the sensitivity of many technological and biological processes to the precise nature of the salt present in solution. The term ‘ion-specific’ encompasses all the circumstances in which the influence of a salt in solution depends on the precise chemical nature of the salt, not just the electrical charge on the ions that form the salt. As such, ion-specific effects abound and have important consequenc ....Unravelling the dominant drivers of ion specificity. This project aims to understand what governs the sensitivity of many technological and biological processes to the precise nature of the salt present in solution. The term ‘ion-specific’ encompasses all the circumstances in which the influence of a salt in solution depends on the precise chemical nature of the salt, not just the electrical charge on the ions that form the salt. As such, ion-specific effects abound and have important consequences in most situations involving solutions, including cellular functions and battery technology. This project will enable us to understand and control the influence of specific ions, building on our recently described fundamental ion-specific series with colloid science experiments and quantum simulations. This project should overcome current challenges in predicting ion-specific effects leading to progress in a wide variety of applications of colloid and interface science, from sensor interfaces to self-assembly.Read moreRead less