Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic model ....Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic models for non-equilibrium electron transport in liquids and biological matter, and its coupling to plasmas. The expected outcomes of this project include progress towards the optimisation of safety/efficacy of future generation plasma medicine devices through detailed understanding of plasma-biological tissue interactions.Read moreRead less
Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the pl ....Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the plasma-liquid interface together with fundamental data describing electron interactions with liquids. The project will develop a state of the art presolvation electron transport model informed by world first measurements of electron cross-sections for radicals and liquids and apply it to model plasma electrochemistry processes.Read moreRead less
Modulating Inflammatory And Fibrogenic Pathways In Kidney Disease Using A Novel Antagonist Of Protease-Activated-Receptor-2
Funder
National Health and Medical Research Council
Funding Amount
$581,116.00
Summary
Chronic kidney disease (CKD) now affects 10% of adults in industrialised countries. Current treatments are largely ineffective. Thus developing better CKD treatments will have substantial public health benefit. Three well established and clinically relevant animal models of kidney disease will be used to test the ability of a new experimental anti-inflammatory drug, developed by members of this research team at The University of Queensland, to prevent or lessen the progression of CKD.
Cellular Regulation Of Receptor Signalling And Cytokine Responses
Funder
National Health and Medical Research Council
Funding Amount
$859,288.00
Summary
Cell surface receptors and signalling pathways elicit the release of cytokines, or chemical messengers, to control inflammation, which is the body’s response to infection or danger. We have discovered a new signalling pathway that can turn off inflammation and help prevent inflammatory disease. Our studies will now define the molecular details of this pathway and show how new and existing drugs targeting this pathway can be optimally used to treat inflammation and cancer.
Low-energy electron transport in soft-condensed biological matter. To obtain optimal accuracy and selectivity of ionising radiation based technologies requires an understanding and quantification of the underpinning fundamental physical processes. This project will focus on developing accurate theoretical models of low-energy electron transport in biological matter which account for new physical mechanisms.
Novel collision experiments with metastable neon atoms in an atom trap. The aim of this project is to investigate collisions involving atoms in long lived excited states (metastable states). The project will utilise a magneto-optical trap to investigate electron-atom collisions as well as interatomic collisions for ultra-cold atoms. The outcomes of such investigations extend scientific knowledge of these important processes as a well as provide data for testing fundamental scattering theories. T ....Novel collision experiments with metastable neon atoms in an atom trap. The aim of this project is to investigate collisions involving atoms in long lived excited states (metastable states). The project will utilise a magneto-optical trap to investigate electron-atom collisions as well as interatomic collisions for ultra-cold atoms. The outcomes of such investigations extend scientific knowledge of these important processes as a well as provide data for testing fundamental scattering theories. This scientific knowledge may lead to further technological advances such as more efficient light sources or a metastable-atom laser that could be used for the production of nano-scale electric circuits.Read moreRead less