Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the poten ....Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the potential to shift disease diagnosis and monitoring closer to the point of care. Expected outcomes include the development of synthetic diamond-based microneedles for the potential to greatly benefit society through improved and affordable healthcare and the development of new high-tech industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100166
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Infrared and Raman microspectroscopic equipment for biomolecular and nanostructural analysis. This project will expand the combined microspectroscopic capabilities of Deakin and Monash Universities to enable high resolution characterisation of a diverse range of components in the fields of biotechnology and nanomaterials. The facility can be applied to pinpointing co-localised compounds within cells through to characterising metal composites, carbon nano tubes and fibres.
Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-as ....Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-assemble into long thermostable fibrils that support cell growth and development. The project’s goal is now to create cost-effective, non-toxic, conducting peptide fibrils that can be used in water or physiological environments for bioelectronics applications.Read moreRead less
Cellulosic and paper-based biosensors for blood analysis. Testing the blood compatibility of an Australian evacuated for surgery; measuring the iron content from India for anemia treatment; identifying the outbreak of malaria in Pakistan; measuring prostate specific antigen/blood screening in your home. These are novel applications for paper biosensors, which will improve health and create new jobs in Australia.
Discovery Early Career Researcher Award - Grant ID: DE140101359
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
Hierarchical 3D metal organic frameworks for the microfabrication of advanced biomedical devices. This project will produce three-dimensional porous structures for use in sensing devices and biomedical implants. Metal-organic frameworks (MOFs) are versatile ultra high surface area materials with controllable pore size, chemical properties and functionalisation. These new materials will be incorporated into portable biosensing devices which are highly sensitive and reliable. The project involves ....Hierarchical 3D metal organic frameworks for the microfabrication of advanced biomedical devices. This project will produce three-dimensional porous structures for use in sensing devices and biomedical implants. Metal-organic frameworks (MOFs) are versatile ultra high surface area materials with controllable pore size, chemical properties and functionalisation. These new materials will be incorporated into portable biosensing devices which are highly sensitive and reliable. The project involves three streams including preparation of the three-dimensional metal scaffolds utilizing state-of-the-art direct manufacturing technologies; integration of MOFs on the three-dimensional metal scaffolds using the metallic structure as the source of the MOF metal ions; and incorporation of bio-active molecules into the three-dimensional hierarchically porous structure for the purpose of bio-device fabrication.Read moreRead less
Reducing gas and ash corrosion in advanced power generation. Advanced power generation using new coal combustion technologies increases energy efficiency and makes carbon dioxide capture possible, but increases the corrosion problems. This project aims to determine the corrosion behaviour of chromia-scale forming iron- and nickel-base alloys in the presence of deposits (coal ashes and salts) under carbon dioxide rich gas atmospheres. The increased understanding of alloy behaviour in hot corrosiv ....Reducing gas and ash corrosion in advanced power generation. Advanced power generation using new coal combustion technologies increases energy efficiency and makes carbon dioxide capture possible, but increases the corrosion problems. This project aims to determine the corrosion behaviour of chromia-scale forming iron- and nickel-base alloys in the presence of deposits (coal ashes and salts) under carbon dioxide rich gas atmospheres. The increased understanding of alloy behaviour in hot corrosive ashes and gases, will permit more effective materials design and selection leading to more efficient and economic technologies for reliable and low cost carbon capture in energy production, waste-energy conversion and related industries.Read moreRead less
High temperature corrosion induced by multiple secondary oxidants . Heat resisting chromia-forming alloys passivate successfully in clean, dry air at temperatures up to about 950°C. However, this performance is degraded by secondary oxidants (carbon, sulphur, chlorine, water vapour), leading to corrosion failure in important industries. The project aims to investigate the effect of these secondary oxidants on corrosion behaviour of chromia-forming alloys, to identify interactions between multipl ....High temperature corrosion induced by multiple secondary oxidants . Heat resisting chromia-forming alloys passivate successfully in clean, dry air at temperatures up to about 950°C. However, this performance is degraded by secondary oxidants (carbon, sulphur, chlorine, water vapour), leading to corrosion failure in important industries. The project aims to investigate the effect of these secondary oxidants on corrosion behaviour of chromia-forming alloys, to identify interactions between multiple oxidants within the scale, to establish the mechanisms of oxide scale penetration by foreign species, and to evaluate scales on different alloy types. The results will provide a basis for improved design/selection of heat resisting chromia-forming alloys, key to power generation industries.Read moreRead less
Two-dimensional plasmonic heterogeneous nanostructures for photocatalysis. This project aims to design and explore two-dimensional heterogeneous photocatalysts that can convert solar energy into usable chemical energy. This project will investigate the correlation between surface plasmonic resonance and photocatalytic activities on the atomic level. Heterogeneous engineering and in-situ investigation of atomic-level photocatalytic dynamics is expected to yield several new full-solar-spectrum pho ....Two-dimensional plasmonic heterogeneous nanostructures for photocatalysis. This project aims to design and explore two-dimensional heterogeneous photocatalysts that can convert solar energy into usable chemical energy. This project will investigate the correlation between surface plasmonic resonance and photocatalytic activities on the atomic level. Heterogeneous engineering and in-situ investigation of atomic-level photocatalytic dynamics is expected to yield several new full-solar-spectrum photocatalysts. The project is expected to contribute to the understanding of the processes and mechanisms underlying photocatalysis, and lead to useable, stable and durable photocatalytics. The outcomes will enable efficient, cost-effective and reliable production of clean energy in a low-emission way.Read moreRead less
Heat-resisting iron-nickel base alloys in challenging new applications: oxygen permeabilities and resistance to internal oxidation. There is a pressing need to develop heat resisting alloys which can function adequately in higher operating temperatures and gas mixtures rich in carbon and hydrogen to be handled in advanced technologies for power generation. The expected outcomes of this project will provide the basis for design/selection of these more corrosion-resistant alloys.