Extension Of The Calcium Intake Fracture Outcome Study
Funder
National Health and Medical Research Council
Funding Amount
$272,025.00
Summary
Osteoporosis is a largely preventable disease yet 1 in 10 Australians have osteoporosis. Every year >64,000 osteoporotic fractures occur, which is one every 8.1 minutes and women are three times as likely to have the disease than men. The Bone and Calcium Research Group at the University of Western Australia, is studying how to prevent osteoporosis in elderly women. This study is called the Calcium Intake Fracture Outcome Study or CAIFOS. During 1998, 1,500 women were recruited to study wheth ....Osteoporosis is a largely preventable disease yet 1 in 10 Australians have osteoporosis. Every year >64,000 osteoporotic fractures occur, which is one every 8.1 minutes and women are three times as likely to have the disease than men. The Bone and Calcium Research Group at the University of Western Australia, is studying how to prevent osteoporosis in elderly women. This study is called the Calcium Intake Fracture Outcome Study or CAIFOS. During 1998, 1,500 women were recruited to study whether a daily calcium supplement for 5 years helps to prevent fractures compared to a diet without a supplement. To do this only half of the women were given calcium supplements and the other half were given matched placebo tablets. Each year the study participants are reviewed and asked whether or not they have broken any bones and have other measurements to monitor their bone health and overall health. The subjects are entering their last year of treatment and will finish the study during 2003. At this appointment all subjects will undergo the same series of measurements that they had at the beginning of the study to determine whether or not they have fractured any bones, improved their bone mass and overall health during the treatment stage. The main outcome of the study is to determine whether calcium is useful as a supplement to prevent osteoporotic fracture in elderly women. If this study finds that fewer women fractured in the calcium treated group compared to the non treated group, given that both groups were similar to begin with, we can say that supplementation with calcium prevents fractures. Thus, public health messages about preventing osteoporosis will be able to direct the community to take supplements to prevent a disease that creates pain and disability in later life. The advantage of this study is that it is studying other aspects of these women health, so we can determine whether the calcium is safe to use and improves people's quality of life.Read moreRead less
Reducing Falls By Improving Knowledge Translation: A Mixed-methods Study To Incorporate Falls Prevention Best-practice Evidence Into Osteoarthritis Care
Funder
National Health and Medical Research Council
Funding Amount
$88,502.00
Summary
Over 50% of people with osteoarthritis (OA) will fall. Resources exist to assist clinicians in the management of OA, but give little or no attention to falls.The association between OA and falls supports the need to incorporate falls prevention strategies into routine OA care. This project aims to reduce falls and fall-related harm in people with OA by creating a list of recommendations for preventing falls that can be incorporated into current OA resources and routine OA care.
Polycystic Ovary Syndrome: Implementation Research Using The Experiences And Perspectives Of Women And Health Professionals To Internationally Translate Guidelines And Evidence Into Practice
Funder
National Health and Medical Research Council
Funding Amount
$695,543.00
Summary
Polycystic ovary syndrome (PCOS) affects up to 1 in 5 women. It is associated with a high risk of obesity, infertility, diabetes, and heart disease. We are updating guidelines for PCOS, yet it is not known how to help women and health professionals use these guidelines. This project will involve women with PCOS and health professionals working together to design high quality resources and link these into clinical care to improve the management of PCOS. This will lead to improved health outcomes.
Evidence-based Physical Activity Promotion In Primary Schools: Improving Children’s Health Through Sustainable Partnerships
Funder
National Health and Medical Research Council
Funding Amount
$1,299,824.00
Summary
Physical inactivity is a leading cause of disease in Australia. Working with the NSW Department of Education, this project aims to increase children’s activity and improve their health. Involving 200 primary schools, we will examine teachers’ adoption of the program and its impact on children’s fitness, well-being and academic performance. The project will provide the evidence and framework for the Department to promote physical activity throughout NSW and a model for adoption in other states.
TRIP Fellowship: Bridging The Evidence Practice Gap In Secondary Prevention In Stroke
Funder
National Health and Medical Research Council
Funding Amount
$146,247.00
Summary
Various medications have been shown to reduce the risk of recurrent vascular disease after stroke. This study aims to improve the frequency of use of these medications in patients discharged from hospital after a stroke.
A Program Of Research In Behavioural Oncology: On The Interface Between Behavioural Research And Cancer Control
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Health behaviours are very important in the early detection of cancer, and they often determine whether a cancer patient will have a good quality of life after cancer treatment. The proposed research program aims to increase our understanding of how to improve health behaviours in order to be able to diagnose cancer as early as possible, and to develop interventions that will help patients to have the best possible care after cancer treatment.
Blood Pressure Lowering In Patients With Chronic Kidney Disease: Evidence From Prospectively Planned Overview Analyses
Funder
National Health and Medical Research Council
Funding Amount
$257,271.00
Summary
This study will provide highly reliable information about the best way of managing blood pressure in people with chronic kidney disease. It will use sophisticated methods to summarize information from 25 large clinical trials and 160,000 participants to determine whether lowering blood pressure reduces the risk of heart disease and further kidney damage.The study will also determine whether currently recommended blood pressure drugs are those which will provide the most benefit.
Understanding Influenza Mortality And The Effects Of Vaccination In The Elderly
Funder
National Health and Medical Research Council
Funding Amount
$446,877.00
Summary
We will analyse mortality from influenza and other causes to estimate the numbers of deaths from other causes that are triggered by influenza in elderly persons, and to test the value of vaccination in preventing those deaths. Our results will help to decide whether an expensive clinical trial is really needed to show the benefit of influenza vaccination on all-cause mortality in the elderly.