Judgment, responsibility, and the life-world: The phenomenological critique of formalism. This project will contribute to building Australia's capacity in the area of phenomenology and connecting Australian researchers into the international network of phenomenology research. More generally the project will contribute to the broader community debate that is currently emerging around issues of the role and limits of knowledge, especially scientific knowledge, but also knowledge as it arises and i ....Judgment, responsibility, and the life-world: The phenomenological critique of formalism. This project will contribute to building Australia's capacity in the area of phenomenology and connecting Australian researchers into the international network of phenomenology research. More generally the project will contribute to the broader community debate that is currently emerging around issues of the role and limits of knowledge, especially scientific knowledge, but also knowledge as it arises and is applied in organisational and social contexts, and the importance of responsibility and judgment even in areas of technical problem-solving and decision-making. In this latter respect, the project is likely to have an impact in more directly applied areas such as policy formation and decision-making across many different areas.Read moreRead less
Gender and the Production of Early Modern French Medicine. This project contributes to a long-term, large-scale research endeavour focused on the interaction of gender and the development of forms of science and technology in history. This project constitutes a significant investigation into the gendering of medical theory and practice. It is an innovative survey of early modern ideas about the production of medical knowledge and practices, about who had the right and authority to determine medi ....Gender and the Production of Early Modern French Medicine. This project contributes to a long-term, large-scale research endeavour focused on the interaction of gender and the development of forms of science and technology in history. This project constitutes a significant investigation into the gendering of medical theory and practice. It is an innovative survey of early modern ideas about the production of medical knowledge and practices, about who had the right and authority to determine medical theory and about how women participated in this framework. The project is expected to result in a major research monograph and a number of key articles.
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Reduction of risk in exploration for petroleum liquids. Australia has an urgent need to establish additional reserves of crude oil. A feature of petroleum exploration in recent decades has been discovery of vast reserves of natural gas but an inability to replace our diminishing reserves of crude oil. Clearly new technology is required to enhance our capability to recognise crude oil-prone rather than gas-prone source rocks. The proposed project will establish the fundamental geochemical pro ....Reduction of risk in exploration for petroleum liquids. Australia has an urgent need to establish additional reserves of crude oil. A feature of petroleum exploration in recent decades has been discovery of vast reserves of natural gas but an inability to replace our diminishing reserves of crude oil. Clearly new technology is required to enhance our capability to recognise crude oil-prone rather than gas-prone source rocks. The proposed project will establish the fundamental geochemical processes that will support the potential exploration techniques, developed with Woodside Energy Limited support.Read moreRead less
Productive Pedagogies, Productive Schools and Gender Reform. This proposal seeks to document policy developments at federal, state and school systems in relation to boys' schooling and measure their effectiveness within a gender equity framework. It also seeks to document and evaluate the effectiveness of school structural and pedagogical reforms geared to better meeting the educational needs of boys without detracting from the education of girls. Finally, the study will map pedagogies and analy ....Productive Pedagogies, Productive Schools and Gender Reform. This proposal seeks to document policy developments at federal, state and school systems in relation to boys' schooling and measure their effectiveness within a gender equity framework. It also seeks to document and evaluate the effectiveness of school structural and pedagogical reforms geared to better meeting the educational needs of boys without detracting from the education of girls. Finally, the study will map pedagogies and analyse their effectiveness against such factors as the gender of the teacher and gender composition of classes, and subject domains, across both primary and secondary schools.Read moreRead less
Psychosomatic Illness in Early Modern Italy: lessons for modern psychiatric theory and practice. This pioneering collaboration between researchers in humanities and medicine will investigate the ways psychosomatic illness was defined and spread in early modern Italy. Epidemics of such illness still occur today and have had a major social and economic impact on Australia in recent decades. Our project will draw lessons for modern psychiatric theory and practice from historical and cultural differ ....Psychosomatic Illness in Early Modern Italy: lessons for modern psychiatric theory and practice. This pioneering collaboration between researchers in humanities and medicine will investigate the ways psychosomatic illness was defined and spread in early modern Italy. Epidemics of such illness still occur today and have had a major social and economic impact on Australia in recent decades. Our project will draw lessons for modern psychiatric theory and practice from historical and cultural differences in the conceptualisation and communication of 'hypochondria'. It will shed light on a very contemporary ethical dilemma in psychiatry: should doctors lie to 'hypochondriacal' patients? It will also contribute to current debates on the role of disease labels and information in the incidence and 'infectiousness' of psychosomatic illness.Read moreRead less
A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Calcification of acrylic hydrogels in abiotic media: mechanism and control. Poly(2-hydroxyethyl methacrylate (PHEMA) and other acrylic hydrogels are extensively used as biomaterials, yet conclusive evidence exists that they have a propensity to calcify following implantation. This process has undesirable consequences on the functionality of various prostheses. Based on preliminary observations that PHEMA can promote the deposition of calcium minerals from media devoid of biological factors, whic ....Calcification of acrylic hydrogels in abiotic media: mechanism and control. Poly(2-hydroxyethyl methacrylate (PHEMA) and other acrylic hydrogels are extensively used as biomaterials, yet conclusive evidence exists that they have a propensity to calcify following implantation. This process has undesirable consequences on the functionality of various prostheses. Based on preliminary observations that PHEMA can promote the deposition of calcium minerals from media devoid of biological factors, which appears thus to be an inherent property of the polymer, the project aims at formulating new hypotheses to explain this phenomenon, and to confirm them experimentally. The "chelation" hypothesis will be validated by modifying the structure of polymers, and the "spontaneous precipitation" hypothesis by assessing the effect of solutes on the equilibrium water content of polymers. NMR and FTIR spectrometric techniques will be used to gain further insight into the mechanism of calcification. Methods to prevent the calcification will potentially result from these experiments, however, anticalcification agents will also be incorporated into hydrogels and their effect evaluated in calcification assays.Read moreRead less
A Genome-wide Search For Genes Underlying The Developmental Origins Of Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$1,022,552.00
Summary
Epidemic rises in the incidence of many chronic diseases such as obesity, type 2 diabetes, hypertension, coronary artery disease and mental illness have occurred in Australia over the last two decades. Antenatal, early life and childhood factors have been consistently associated with the development of such diseases. We propose to conduct a genome-wide scan in an exceptional longitudinal birth cohort in order to identify the genetic mechanisms linking early life event and adult disease.