STudy Of Risk Assessment To Reduce Complications In Patients Following Noncardiac SurgerY (STRATIFY)
Funder
National Health and Medical Research Council
Funding Amount
$436,000.00
Summary
Cardiac problems account for many complications in patients undergoing major non-cardiac surgery, and even apparently minor cardiac damage is a marker of high risk for subsequent adverse events. Unfortunately, while money and effort is expended on identifying patients at risk, the appropriate response to this risk is quite unclear. The performance of bypass surgery or balloon angioplasty in order to treat the underlying coronary disease of at-risk patients is used in other situations, and reduce ....Cardiac problems account for many complications in patients undergoing major non-cardiac surgery, and even apparently minor cardiac damage is a marker of high risk for subsequent adverse events. Unfortunately, while money and effort is expended on identifying patients at risk, the appropriate response to this risk is quite unclear. The performance of bypass surgery or balloon angioplasty in order to treat the underlying coronary disease of at-risk patients is used in other situations, and reduces longterm risk. However, in many patients undergoing major noncardiac surgery, this approach may be inappropriately aggressive, as these patients are often elderly, have other diseases that make heart operations more difficult and risky than usual, and in any case may have a reduced life expectancy from the disease necessitating the operation. As the most critical issue is to ensure that patients undergo their surgery uneventfully, an alternative is the use of intensive medical therapy to protect the heart. This multicentre study, based at Brisbane hospitals that perform large numbers of major operations, will follow up patients for complications, and outcome (including quality of life) will be assessed six months after the operation. We will address two important questions about the efficacy and cost of risk reduction strategies. First, in patients at higher levels of risk and with a positive stress test, could a combination of medical therapy designed to protect the heart be as effective as current approaches, which include the performance of bypass surgery or coronary balloon angioplasty? Second, in patients identified as being at some risk - but low risk - are drugs sufficiently effective to avoid the need for further testing to quantify risk? As the population continues to age, the numbers of at risk patients undergoing major surgery will increase, and answers to these questions will provide important information to guide their management.Read moreRead less
Contingent development in regional India: ethnographies of neoliberal globalisation in Gujarat and West Bengal. This project aims to understand the regional impacts of globalisation in India by comparing and contrasting two regional towns and their hinterlands (Anand, Gujarat and Darjeeling, West Bengal). Develop a more comprehensive, localised and regionalised account of the neoliberal globalisation process in India.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668038
Funder
Australian Research Council
Funding Amount
$175,000.00
Summary
From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industri ....From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industries, and find application in human and animal medicine. They will enhance the health and well-being of the Australian community and engender a sense of wonder in susceptible members of this community.Read moreRead less
How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. ....How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. It also looks at climate anxiety management across generations and climate histories, drawing out pessimistic/optimistic narratives about the future to enable action, resilience, and hope. It will produce an evidence base and photo-voice/documentary resources to help parents and support organisations combat climate anxiety.Read moreRead less
Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world ....Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world and our experience of the world, and aims to reconcile the two by bridging the gap between lived experience and scientific findings. The project will provide a range of ways of bridging the tension between these physical theories with our lived experience.Read moreRead less
Reducing plate waste in hotels - which interventions are most effective? This project aims to quantify the comparative effectiveness of belief-based and choice-architecture-based interventions in reducing food waste generated by tourists at hotel buffets. Expected outcomes include: new insights into effective triggers of pro-environmental tourist behaviour; the first empirical data on carbon emissions caused by plate waste in tourism; an automatic plate waste measurement system and benchmarking ....Reducing plate waste in hotels - which interventions are most effective? This project aims to quantify the comparative effectiveness of belief-based and choice-architecture-based interventions in reducing food waste generated by tourists at hotel buffets. Expected outcomes include: new insights into effective triggers of pro-environmental tourist behaviour; the first empirical data on carbon emissions caused by plate waste in tourism; an automatic plate waste measurement system and benchmarking app for monitoring and comparison; and effective practical measures to reduce avoidable food leftovers generated by tourists. This should provide significant benefits by: lowering food cost for the struggling tourism industry, reducing carbon emissions, and contributing to Australia’s aim of halving food waste by 2030.Read moreRead less
Transnational seafood commodity chains and the coastal poor in the maritime frontiers of the Asia-Pacific. This research aims to understand the social mechanisms by which access to the benefits of transnational seafood commodity chains in the Asia-Pacific are gained, maintained and controlled. This project will use a conceptual framework that focuses on key social relations of gender, class and ethnicity, and the key societal changes of land-use change, migration and conservation. This project o ....Transnational seafood commodity chains and the coastal poor in the maritime frontiers of the Asia-Pacific. This research aims to understand the social mechanisms by which access to the benefits of transnational seafood commodity chains in the Asia-Pacific are gained, maintained and controlled. This project will use a conceptual framework that focuses on key social relations of gender, class and ethnicity, and the key societal changes of land-use change, migration and conservation. This project offers a novel research framework for a pressing cluster of economic, environmental and social challenges in the Asia-Pacific, and will inform research and policy for poverty reduction, economic development, environmental management and food security. Read moreRead less
Resolving the threat of ocean deoxygenation to coral resilience. This project aims to uncover the role low oxygen plays in shaping healthy corals over space and time. Climate change and land use development are rapidly deoxygenating shallow water coral reefs, yet we have no knowledge of how less oxygen availability affects critical life history factors that govern coral resilience: growth, reproduction, and stress tolerance. This project unites a multidisciplinary team of experts to, for the fir ....Resolving the threat of ocean deoxygenation to coral resilience. This project aims to uncover the role low oxygen plays in shaping healthy corals over space and time. Climate change and land use development are rapidly deoxygenating shallow water coral reefs, yet we have no knowledge of how less oxygen availability affects critical life history factors that govern coral resilience: growth, reproduction, and stress tolerance. This project unites a multidisciplinary team of experts to, for the first time, couple advanced oxygen sensing, metabolic physiology, coral reproductive and stress biology to transform our understanding of oxygen thresholds that are diagnostic of reduced coral competitive fitness across life stages (adults, juveniles, larvae), needed to improve coral reef ecosystem management.Read moreRead less
Biohumanities: Philosophical, Historical, and Socio-Cultural Studies of Contemporary Bioscience. Improving understanding of the meaning and implications of contemporary bioscience, especially genetics and molecular biology, through bioliterate research in the humanities and social sciences, and conversely through better assimilation of bioscience and its significance by the humanities and social sciences. The research will be conducted in close collaboration with the Australian scientific commun ....Biohumanities: Philosophical, Historical, and Socio-Cultural Studies of Contemporary Bioscience. Improving understanding of the meaning and implications of contemporary bioscience, especially genetics and molecular biology, through bioliterate research in the humanities and social sciences, and conversely through better assimilation of bioscience and its significance by the humanities and social sciences. The research will be conducted in close collaboration with the Australian scientific community and will be disseminated back to the scientific community, to the humanities and to the Australian public. The project will bring to Australia the strengths of the applicant's existing collaborations with leading research centres in this field in the USA, UK and Canada.Read moreRead less