A Population Based Investigation Of Early Life Lung Development And Immune Programming
Funder
National Health and Medical Research Council
Funding Amount
$176,719.00
Summary
Asthma and allergic diseases cost Australia in excess of 7.8 billion per year. We are yet to identify any substantially effective preventative strategies. The applicant is a highly successful early stage clinician-researcher based in regional Victoria. This collaborative project will involve extending two existing NHMRC projects, in addition to establishing a new unselected Australian birth cohort, in to investigate the early life gene-environment determinants of asthma and allergic disease.
I am a research scientist measuring inhaled and exhaled bioaerosols, such as viruses and allergens, to determine their clinical role in human respiratory diseases, particularly asthma.
T Cell PKC Expression As A Novel Neonatal Predictor And Modulator Of Allergic Disease.
Funder
National Health and Medical Research Council
Funding Amount
$557,939.00
Summary
This application will further assess the role of a novel biological predictor of allergic disease, which appears more accurate than any previous marker (based on preliminary data). This is highly relevant to development of predictive tools that could be ultimately used in clinical practice. We will also assess this marker as a potential target for disease prevention, as our preliminary data also indicates that it can be modified by an early intervention aimed at preventing allergic disease.