Development of non-iodinated, non ionic, water-soluble metal based compounds for clinical administration as radiographic contrast media. Every year Australia spends more than $50 million on importing radiographic contrast media, in an international market worth more than $1 billion pa. Existing iodine based agents, which currently cause major adverse reactions in 1% of the population, could be replaced by new metal based imaging media which provide both enhanced contrast and greater patient safe ....Development of non-iodinated, non ionic, water-soluble metal based compounds for clinical administration as radiographic contrast media. Every year Australia spends more than $50 million on importing radiographic contrast media, in an international market worth more than $1 billion pa. Existing iodine based agents, which currently cause major adverse reactions in 1% of the population, could be replaced by new metal based imaging media which provide both enhanced contrast and greater patient safety and comfort. Even a small fraction of the international market would generate millions of dollars in overseas income from a range of potential sources, including licensing/royalties to export by a local start-up company, and expansion of rare earth mining in Australia.Read moreRead less
Intelligent Image Processing Techniques for Novel Biomarker Discovery. This project will make an impact on Australia's international research profile by seeking a solution to a worldwide challenging problem in biomarker discovery for the detection of diseases at an early stage which requires the incorporation of the skills and knowledge from biology, medicine, engineering, computer science, and information technology. The successful outcomes of this research will make an impact on Australia's e ....Intelligent Image Processing Techniques for Novel Biomarker Discovery. This project will make an impact on Australia's international research profile by seeking a solution to a worldwide challenging problem in biomarker discovery for the detection of diseases at an early stage which requires the incorporation of the skills and knowledge from biology, medicine, engineering, computer science, and information technology. The successful outcomes of this research will make an impact on Australia's engagement in using advanced image analysis and intelligent methods for the emerging research and development of targeted drug discovery. Read moreRead less
Evolutionary algorithms for problems in functional genomics data analysis. Skin cancer has a high incidence in the Australian population. Schizophrenia is a psychiatric disorder that affects a significant proportion of the population worldwide. Both illnesses have genetic roots and can be triggered by environmental factors. We will uncover genetic relationship to disease and their responses to environmental conditions using computational methods and mathematical algorithms that can aid in the de ....Evolutionary algorithms for problems in functional genomics data analysis. Skin cancer has a high incidence in the Australian population. Schizophrenia is a psychiatric disorder that affects a significant proportion of the population worldwide. Both illnesses have genetic roots and can be triggered by environmental factors. We will uncover genetic relationship to disease and their responses to environmental conditions using computational methods and mathematical algorithms that can aid in the determination of function, especially in disease states. Understanding the complex genetic interactions that trigger these illnesses would give great benefits in preventive health care, skin cancer and schizophrenia genetic basis, and may lay the ground for building new methods for "personalized medicine".
Read moreRead less