Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668038
Funder
Australian Research Council
Funding Amount
$175,000.00
Summary
From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industri ....From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industries, and find application in human and animal medicine. They will enhance the health and well-being of the Australian community and engender a sense of wonder in susceptible members of this community.Read moreRead less
Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approac ....Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approaches. The proposal critically underpins and further advances Australia's leading position in both breakthrough science as well as advanced materials. Due to its significant scientific breadth and large coverage of both synthetic and physical aspects of polymer science, the project also provides a significant platform for research training at both honours and PhD level.Read moreRead less
Polymerization Mechanism and Kinetics of 1,1-Disubstituted Monomers. This project focuses on two exciting research areas: (I) we have found that an oxygen atom b to the double bond activates radical polymerization, making a whole new family of polymeric structures accessible, and (II) we have strong preliminary data that demonstrates a very large solvent effect on propagation and termination reactions for acrylic monomers with an a-CH2OH functionality, suggesting that significant control can be ....Polymerization Mechanism and Kinetics of 1,1-Disubstituted Monomers. This project focuses on two exciting research areas: (I) we have found that an oxygen atom b to the double bond activates radical polymerization, making a whole new family of polymeric structures accessible, and (II) we have strong preliminary data that demonstrates a very large solvent effect on propagation and termination reactions for acrylic monomers with an a-CH2OH functionality, suggesting that significant control can be exerted over the polymerization process using additives. Additionally, we demonstrate that polymers containing repeat units with an a-CH2OH functionality can undergo reversible cyclization, enabling a whole range of novel functional materials.Read moreRead less
Mechanisms in Catalytic Chain Transfer Polymerization. The aim of the proposed research is to gain more insight into the mechanisms underlying catalytic chain transfer polymerization, a relatively recent controlled radical polymerization technique which is finding an increasing number of industrial applications, especially in the paint and coatings industry. An improved understanding of the catalytic chain transfer process, of which some very important features are still poorly understood, will ....Mechanisms in Catalytic Chain Transfer Polymerization. The aim of the proposed research is to gain more insight into the mechanisms underlying catalytic chain transfer polymerization, a relatively recent controlled radical polymerization technique which is finding an increasing number of industrial applications, especially in the paint and coatings industry. An improved understanding of the catalytic chain transfer process, of which some very important features are still poorly understood, will ultimately lead to better catalyst design and improved process and product control. This in turn will lead to novel polymeric materials.Read moreRead less
Synthesis of oligomers in dense carbon dioxide. The aim of the project is to develop a novel technique for the synthesis of low molecular weight polymers (oligomers) using dense carbon dioxide as a polymerisation solvent. The use of elevated pressure is the major impediment to the commercialisation of such technology. The technique proposed in this project will enable oligomers to be produced at greatly reduced operating pressures and may lead to a more general procedure for conducting other t ....Synthesis of oligomers in dense carbon dioxide. The aim of the project is to develop a novel technique for the synthesis of low molecular weight polymers (oligomers) using dense carbon dioxide as a polymerisation solvent. The use of elevated pressure is the major impediment to the commercialisation of such technology. The technique proposed in this project will enable oligomers to be produced at greatly reduced operating pressures and may lead to a more general procedure for conducting other types of polymer synthesis in dense carbon dioxide.Read moreRead less
Controlled/living radical polymerization in environmentally friendly miniemulsions induced by compressed carbon dioxide for synthesis of nanoparticles and well-defined polymer. Controlled/living radical polymerization is a technique for precise synthesis of polymer by radical polymerization, which has revolutionized polymer synthesis in terms of accessible polymer structures. However, controlled/living radical polymerization has yet to gain a strong foothold in industry mainly due to problems as ....Controlled/living radical polymerization in environmentally friendly miniemulsions induced by compressed carbon dioxide for synthesis of nanoparticles and well-defined polymer. Controlled/living radical polymerization is a technique for precise synthesis of polymer by radical polymerization, which has revolutionized polymer synthesis in terms of accessible polymer structures. However, controlled/living radical polymerization has yet to gain a strong foothold in industry mainly due to problems associated with its implementation in (aqueous) dispersed systems. The present Proposal addresses this key challenge by a novel environmentally friendly and versatile method for aqueous miniemulsion preparation by use of compressed carbon dioxide. Controlled/living radical polymerization in dispersed systems generates polymeric nanoparticles, which are of importance in many advanced and emerging technologies.Read moreRead less
Synthesis and Characterization of Novel Hybrid star polymers grown from carbohydrate clusters. The aim of the project is to make complex polymer architectures based on stars grown from sugar clusters. The star molecules are expected to have unique properties for transporting guest molecules in drug delivery systems. The outcome will be the development of totally biodegradable, non-toxic cluster/star structures capable of complexing to drugs. This is the first attempt to utilise these clusters ....Synthesis and Characterization of Novel Hybrid star polymers grown from carbohydrate clusters. The aim of the project is to make complex polymer architectures based on stars grown from sugar clusters. The star molecules are expected to have unique properties for transporting guest molecules in drug delivery systems. The outcome will be the development of totally biodegradable, non-toxic cluster/star structures capable of complexing to drugs. This is the first attempt to utilise these clusters, with sugar-based vinyl monomers for star synthesis.Read moreRead less
Novel Hydrogels for Bioseparations in Clinical Applications. The project aims to design and synthesise new highly swollen hydrophilic membranes for use in biological separation processes and purifications such as the removal of viruses from blood. Typical membrane problems like membrane fouling or low flux should be minimized by a narrow pore size distribution. The regular nano-patterning should be obtained by molecular impriniting technique. Novel thermoresponsive polymers, which will be polyme ....Novel Hydrogels for Bioseparations in Clinical Applications. The project aims to design and synthesise new highly swollen hydrophilic membranes for use in biological separation processes and purifications such as the removal of viruses from blood. Typical membrane problems like membrane fouling or low flux should be minimized by a narrow pore size distribution. The regular nano-patterning should be obtained by molecular impriniting technique. Novel thermoresponsive polymers, which will be polymerized via controlled free radical polymerization techniques, will be used as biocompatible membrane material.Read moreRead less
Polymer Stabilized and Bio-functionalised Metal Nanoparticles As Potential Vectors For Drug Therapies. The project aims to make novel nanoparticles (extremely small, nano means one billionth of a metre) that carry medicines to very specific sites of the body and then release them. This would result in much improved outcomes for conventional chemotherapy but may also allow new gene therapies where diseases can be silenced at their source.
Controlled Grafting of Polymer Surfaces for Biotechnology Applications. The aim of this project is to utilise novel polymerization methods to create highly functional polymer surfaces. We anticipate that the resultant structures will be useful for a number of applications including solid-phase organic synthesis and proteomics.