Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100030
Funder
Australian Research Council
Funding Amount
$270,000.00
Summary
Test-bed for Wide-Area Software Defined Networking Research. Test bed for wide-area software defined networking research: This project aims to develop a wide-area test bed, spanning ten organisations, for conducting research and experimentation in the emerging disruptive technology of Software Defined Networking (SDN). SDN is likely to bring long-term transformation to the networking industry, much like cloud computing did, by enabling dynamic virtualised elastic network services under software ....Test-bed for Wide-Area Software Defined Networking Research. Test bed for wide-area software defined networking research: This project aims to develop a wide-area test bed, spanning ten organisations, for conducting research and experimentation in the emerging disruptive technology of Software Defined Networking (SDN). SDN is likely to bring long-term transformation to the networking industry, much like cloud computing did, by enabling dynamic virtualised elastic network services under software control. The test bed will empower Australian researchers in network technologies and dependent applications (for example, multimedia and security) to collaboratively develop and demonstrate novel ideas at scale. This is expected to benefit Australia by giving our researchers international recognition in this nascent area, and developing a national talent pool for local industry.Read moreRead less
Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by ....Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by modifying the levels of road and rail crossings and providing guard rails in the recesses of these modified level crossings. The theories are intended be developed using nonlinear dynamic computational methods and laboratory experiments. The outcomes are expected to enable reduction in the severity of level crossing accidents and hence save lives and costs of derailment.Read moreRead less
ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this te ....ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this team with the foremost international authorities and leading industry players in the area of sensor networks. This research network will guide collaborative research that will ensure Australia to play a world leading role in sensor network development and implementation.
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Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlyin ....Visual Analytics for Next Generation Sequencing. Next-generation sequencing technologies have brought a revolution in biology and healthcare, while taxing the ability of scientists and clinicians to identify and process relevant data, to make sense of it all and communicate it to others in a concise and meaningful way. This project aims to tackle this problem through fundamentally new approaches to data selection and visualisation at very large scale, actively encoding for insight into underlying biological and biomedical processes, bringing sustainable discovery of new relationships and variations within the data. The project aims to support new approaches to medical diagnosis and treatment, and offer crucial lessons to address the broader challenge of understanding large, complex data sets.Read moreRead less
Novel test and design methods for base course reinforced flexible pavements. This project aims to develop the mechanics of geosynthetic-reinforced flexible pavements as an urgent need for the Australian pavement industry to build more sustainable and economical roads. Novel laboratory test apparatus and in-situ test programs, and mathematical models will be developed, for the first time, to capture the responses of reinforced base courses in a complete and optimised way to determine the paramete ....Novel test and design methods for base course reinforced flexible pavements. This project aims to develop the mechanics of geosynthetic-reinforced flexible pavements as an urgent need for the Australian pavement industry to build more sustainable and economical roads. Novel laboratory test apparatus and in-situ test programs, and mathematical models will be developed, for the first time, to capture the responses of reinforced base courses in a complete and optimised way to determine the parameters for pavement design and performance evaluation. The outcomes will enable reliable prediction of reinforced pavement behaviour, leading to better-performing geosynthetic products and more resilient pavements, reduced material usage and damage in pavements, and less environmental impact and maintenance cost.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100006
Funder
Australian Research Council
Funding Amount
$3,937,625.00
Summary
ARC Training Centre for Advanced Technologies in Rail Track Infrastructure. The ARC Training Centre for Advanced Technologies in Rail Track Infrastructure aims to transform Australia’s rail construction and maintenance technologies through specialist training of industry-focused researchers. Generation of new knowledge and close collaboration with companies within the rail supply chain will result in enhanced rail capacity and supply chain efficiency across the rail network. This will include in ....ARC Training Centre for Advanced Technologies in Rail Track Infrastructure. The ARC Training Centre for Advanced Technologies in Rail Track Infrastructure aims to transform Australia’s rail construction and maintenance technologies through specialist training of industry-focused researchers. Generation of new knowledge and close collaboration with companies within the rail supply chain will result in enhanced rail capacity and supply chain efficiency across the rail network. This will include increased axle loads and higher speeds, greater safety margins, reduced construction and maintenance costs, and a body of competent railway professionals in the nation’s work force.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100001
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end ....ARC Training Centre for Automated Vehicles in Rural and Remote Regions. The Centre will build skills and capability to test and deploy safe, socially acceptable, automated vehicles (AV) for rural, regional and remote Australian public roads, where manufacturing, agriculture, mining and defence industries face significant challenges of driver shortages, rising costs, long distances, rough roads, and environmental impacts. The centre will unite technology providers, regulators, government and end users with world-leading interdisciplinary researchers to create new human-AV systems, datasets, frameworks, case studies, platforms, and a vastly upskilled workforce. This will reduce transport costs, increase capacity, boost supply chain efficiency and resilience, improve road safety, and elevate Australian capability.Read moreRead less
ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longi ....ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longitudinal family cohort study and children’s technology laboratories. The Centre will address tensions in a contested field to inform government and non-government policy, technology innovation, and develop programs and guidelines for children, families, educators and technology developers. Read moreRead less