The Implementation Of MinimAlly INvasivE Hysterectomy (IMAGINE) Trial
Funder
National Health and Medical Research Council
Funding Amount
$656,854.00
Summary
Hysterectomy is the most common surgical [procedure among Australian women. Too many women still receive an open abdominal surgery, because too few Australian obstetricians and gynaecologists practice laparoscopic hysterectomy. This partnership will develop a model to systematically train practicing surgeons in advanced laparoscopic techniques. If successful, the model can be rolled out state and nationwide and also adapted for teaching future innovations in surgery.
Quality Improvement In Indigenous Primary Health Care: Leveraging Effective Ambulatory Practices (LEAP)
Funder
National Health and Medical Research Council
Funding Amount
$1,144,570.00
Summary
Although much is known about best practice in quality improvement in Indigenous Primary Health Care Services, getting this into practice remains challenging. The LEAP project works in partnership with health services to i) identify challenges faced when improving care; ii) design and trial interventions to address these challenges; and iii) evaluate how this process works in different settings.
An Innovation Platform For Systems-Wide Improvement In Indigenous Primary Health Care
Funder
National Health and Medical Research Council
Funding Amount
$2,592,418.00
Summary
The CRE for Integrated Quality Improvement (CRE-IQI) will improve Aboriginal and Torres Strait Islander health outcomes by accelerating and strengthening large-scale primary health care (PHC) quality improvement efforts. As an Innovation Platform, it will build on and extend the work of the ABCD National Research Partnership, and leverage the efforts of researchers, service providers and policy makers to address priority areas for development of IQI in Aboriginal and Torres Strait Islander PHC.
Quality Improvement In Aboriginal Primary Health Care: Lessons From The Best To Better The Rest.
Funder
National Health and Medical Research Council
Funding Amount
$617,427.00
Summary
High performing primary health care (PHC) services are essential to "close the gap" in Aboriginal and Torres Strait Islander health outcomes. Little previous research has investigated the contextual factors around a particular service that influence the success of quality improvement initiatives. We aim to transfer knowledge about the processes that facilitate the success of quality improvement initiatives in these services whilst building research and evaluation capacity in the services.
Improving Outcomes For People With Acute Mental Illness In The Emergency Department: A Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$251,470.00
Summary
Currently, there is a lack of integration between emergency and mental health information systems. This means it is difficult for clinicians to comprehensively understand a patient’s interaction with other services – an important aspect when making treatment decisions. Our study will link 5 years of information from health, police and national death databases. This will identify areas where emergency services can be improved for vulnerable people seeking help for their mental health problem.
Promoting Activity For Frail Aged In Post-acute Hospital Settings: A Randomised Controlled Trial Of Accelerometry
Funder
National Health and Medical Research Council
Funding Amount
$542,119.00
Summary
Keeping older people in hospital actively mobile is a vital objective of high quality aged care. Using accelerometers, the Centre for Research in Geriatric Medicine at the University of Queensland, and its partner, the CSIRO e-health Research Centre, are trialing a method of promoting activity in older rehabilitation patients. Potentially, a system of _activity management� could solve an age old problem in hospital care of older people.
Maximising pineapple production for Australian farmers using genome editing. This project addresses the single biggest issue affecting the viability of pineapple farming in Australia and internationally: premature flowering leading to supply collapse. We aim to develop CRISPR technology to breed new pineapple varieties using non-GM approaches. Expected outcomes include the production of pineapples with resistance to premature flowering, as well as the technologies to deliver additional improveme ....Maximising pineapple production for Australian farmers using genome editing. This project addresses the single biggest issue affecting the viability of pineapple farming in Australia and internationally: premature flowering leading to supply collapse. We aim to develop CRISPR technology to breed new pineapple varieties using non-GM approaches. Expected outcomes include the production of pineapples with resistance to premature flowering, as well as the technologies to deliver additional improvements in the future. The new varieties will benefit farmers through increased production, maximising supply capability for a rapidly growing internal demand. This will benefit Australian pineapple producers through higher profitability in existing markets, as well as enabling expansion into international and future markets.Read moreRead less
Manipulation of carbon partitioning to enhance the value of sugarcane. Manipulation of carbon partitioning to enhance the value of sugarcane. This project aims to develop enhanced varieties of sugarcane, a highly efficient crop for capturing carbon in plant biomass. This project will use genomic and metabolomic tools to investigate the biochemical and molecular genetic control of carbon partitioning into the major components of sugarcane biomass; identify key genetic controls of sucrose, cellulo ....Manipulation of carbon partitioning to enhance the value of sugarcane. Manipulation of carbon partitioning to enhance the value of sugarcane. This project aims to develop enhanced varieties of sugarcane, a highly efficient crop for capturing carbon in plant biomass. This project will use genomic and metabolomic tools to investigate the biochemical and molecular genetic control of carbon partitioning into the major components of sugarcane biomass; identify key genetic controls of sucrose, cellulose, hemicellulose and lignin biosynthesis; and establish strategies for genetic selection of sugarcane genotypes with desirable biomass components. Anticipated outcomes are an optimised industrial sugarcane crops with higher sugar content and other biomass components designed for high value end uses such as bio-energy or bio-material production.Read moreRead less
A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Combining molecular plant physiology and breeding to improve canola (Brassica napus) performance in dry environments. Canola is Australia's most important oilseed crop with 1,400,000 hectares sown annually worth $560m. The major abiotic factor limiting canola production in Australia is water availability. Transpiration efficiency (TE) is a trait with potential to contribute to improved drought tolerance of grain crops. This project seeks to select canola germplasm with improved TE by indirect s ....Combining molecular plant physiology and breeding to improve canola (Brassica napus) performance in dry environments. Canola is Australia's most important oilseed crop with 1,400,000 hectares sown annually worth $560m. The major abiotic factor limiting canola production in Australia is water availability. Transpiration efficiency (TE) is a trait with potential to contribute to improved drought tolerance of grain crops. This project seeks to select canola germplasm with improved TE by indirect selection for carbon-isotope-discrimination. In addition we will use the extensive Brassica-Arabidopsis genome synteny to locate and alter the expression of genes involved in TE using Arabidopsis as a model. The longterm aim is to improve the reliability and overall grain production of canola in Australia. Read moreRead less