A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water ....Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water and soil should lead to deeper understanding of the dynamics, variation and transfer of genetic material within these resources’ microbial communities, strategies to manage microbial diversity, and improved productivity and long-term sustainability for these resources.Read moreRead less
Work life after a diagnosis of breast, prostate and colorectal cancer: Major disruption or work as usual. Each year, over 40,000 working-age individuals (as well as their families and workplaces) are affected by a diagnosis of cancer. This novel and important study will, for the first time in Australia, identify the extent and effects of loss of skilled workers from the workforce because of a diagnosis of breast, prostate or colorectal cancer and will lead to the development of new interventions ....Work life after a diagnosis of breast, prostate and colorectal cancer: Major disruption or work as usual. Each year, over 40,000 working-age individuals (as well as their families and workplaces) are affected by a diagnosis of cancer. This novel and important study will, for the first time in Australia, identify the extent and effects of loss of skilled workers from the workforce because of a diagnosis of breast, prostate or colorectal cancer and will lead to the development of new interventions that help people to recover from cancer. This project is critical to help advance health and labour policies in Australia which currently faces an ageing population, global economic unrest and rising unemployment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100066
Funder
Australian Research Council
Funding Amount
$260,000.00
Summary
Enhanced modelling capacity for the Industrial Ecology Virtual Laboratory. Enhanced modelling capacity for the Industrial Ecology Virtual Laboratory:
This project aims to enable Australian research leaders working on the integrated sustainability assessment of policies, products and projects to collaborate in the Industrial Ecology Virtual Laboratory (IELab). It seeks to develop and implement an enhanced modelling capability and suite of online analytical tools to support sustainability scienti ....Enhanced modelling capacity for the Industrial Ecology Virtual Laboratory. Enhanced modelling capacity for the Industrial Ecology Virtual Laboratory:
This project aims to enable Australian research leaders working on the integrated sustainability assessment of policies, products and projects to collaborate in the Industrial Ecology Virtual Laboratory (IELab). It seeks to develop and implement an enhanced modelling capability and suite of online analytical tools to support sustainability scientists and analysts from Australia and abroad conducting research projects of national and international significance. In particular, the project would provide policy-makers, investors and communities with detailed and tailored information to help make better decisions about a sustainable future. By upgrading IELab hardware and analytical and modelling software, the project would be versatile and flexible and remain up to date.Read moreRead less
Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Enhancing social research in Australia using dual-frame telephone surveys. The growing surge in mobile phones and mobile-phone only households has had a significant impact on the representativeness of social surveys and accuracy of social outcome measures. This project will develop methods for generating sampling lists of both types of telephone numbers to improve population coverage and accuracy of outcome measures.
Creating a smart city through internet of things. This project will deliver smart new ways of urban monitoring using ubiquitous sensing and data analysis for city management and sustainability. It will deliver researcher training, global clientele for local technology and a platform for local industry growth.
Developing a collaborative approach to ageing well in the community. This project is located within an identified national research priority that of Ageing Well, Ageing Productively. It is also consistent with the goals of the ARC NHMRC Research Network in Ageing Well. While much of the Australian policy debate has previously focused on the negative implications associated with population ageing, it is essential to explore how older people and local communities can age well. The benefit of this ....Developing a collaborative approach to ageing well in the community. This project is located within an identified national research priority that of Ageing Well, Ageing Productively. It is also consistent with the goals of the ARC NHMRC Research Network in Ageing Well. While much of the Australian policy debate has previously focused on the negative implications associated with population ageing, it is essential to explore how older people and local communities can age well. The benefit of this project is that it helps translate national policy directives / goals by offering a framework for action at the local level. Further benefit will derive from the project by enhancing options for community engagement of older people.Read moreRead less
Special Research Initiatives - Grant ID: SR0354739
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Network on eRAM: Environmental Risk Assessment and Management. The proposed network seeks to provide an understanding of the relationship between environmental agents/factors and public health. It provides Australia's first, unified effort to undertand the processes involved at a whole-of-environment level. By virtue of its operation, the network will co-ordinate and expand upon the largely scattered and matrix-specific research in this field that currently takes place. It will permit evaluat ....Network on eRAM: Environmental Risk Assessment and Management. The proposed network seeks to provide an understanding of the relationship between environmental agents/factors and public health. It provides Australia's first, unified effort to undertand the processes involved at a whole-of-environment level. By virtue of its operation, the network will co-ordinate and expand upon the largely scattered and matrix-specific research in this field that currently takes place. It will permit evaluation of environmental agents/factors, as they relate to public health under prevailing environmental conditions. Thus, the major outcome of the network will be effective risk assessment of the expected real-time effects of environmental agents/factors on public health.Read moreRead less
Social networks and subjective wellbeing in Australia, China and the United Kingdom. Governments, industry and the community increasingly recognise that people's networks matter for health and wellbeing. For the first time this project compares developed and developing societies, Australia, China and the United Kingdom, to see how social networks affect well-being in different cultural and societal contexts.