A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
National Centre Of Research Excellence To Improve Management Of Peripheral Arterial Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,618,637.00
Summary
Approximately 15% of adults have blockages or weakness of major arteries in the periphery, associated with impaired quality of life and a high mortality. Significant management deficiencies for these problems include limited diagnostic, prognostic and treatment options, as well as poor adoption of evidence based practice. The proposed national centre will bring together a group of experts in the field to instigate a number of initiatives to improve patient management.
Improving The Prevention, Treatment And Management Of Cardiovascular & Chronic Disease In The Community
Funder
National Health and Medical Research Council
Funding Amount
$774,540.00
Summary
The identification, prevention and management of cardiovascular and chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises modern epidemiological research methods involving large scale clinical trials, registries and epidemiological modelling to advance our understanding and provide new directions for cardiovascular disease prevention and management.
The identification, prevention and management of chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises a number of research methods to advance our understanding and provide new directions for cardiovascular disease prevention and management.
QUality Improvement In Primary Care To Prevent Hospitalisations And Improve Effectiveness And Efficiency Of Care For People Living With Heart Disease (QUEL)
Funder
National Health and Medical Research Council
Funding Amount
$828,305.00
Summary
Heart disease accounts for a great number of deaths and admissions to hospital. We aim to improve ongoing prevention for people with heart disease by supporting general practices to use their data and provide more systematic care. We propose a randomised trial to determine whether a practice level strategy reduces cardiovascular events and hospitalisations and saves money. The research will directly inform government decision-making and policy regarding primary care incentive payment programs.
Mitigating the risk of cyanobacterial blooms in wastewater ponds. Cyanobacterial blooms in wastewater treatment plants impact on effluent quality and the utility of recycled water, posing a significant risk to the economy, the environment and public health. To understand the causes of cyanobacterial blooms in pond-based wastewater treatment plants and the risk they pose, this project will use the latest molecular techniques to examine how the microbial communities within these systems interact w ....Mitigating the risk of cyanobacterial blooms in wastewater ponds. Cyanobacterial blooms in wastewater treatment plants impact on effluent quality and the utility of recycled water, posing a significant risk to the economy, the environment and public health. To understand the causes of cyanobacterial blooms in pond-based wastewater treatment plants and the risk they pose, this project will use the latest molecular techniques to examine how the microbial communities within these systems interact with each other and their surrounding environment to form blooms and produce toxins and other harmful metabolites. Such knowledge will inform risk assessment and provide strategies for the mitigation of future bloom events, improving the security of our increasingly valuable recycled water resources.Read moreRead less
Performance of waste stabilisation ponds: controlling factors, novel performance indicators, and risk assessment. As the world population increases, maintaining robust, cost-effective and environmentally safe wastewater treatment systems is of vital importance. This project will enhance the ability to design, operate and manage Australia's extensive wastewater infrastructure for safer and more sustainable water resources in Australia and the world.
The role of public culture in the construction of contemporary Australian literature. Literature is not simply a body of texts; it is a cultural technology, affected by changing patterns of production and consumption. Witness the 'cult of celebrity', the phenomenal recent growth of literary festivals, literary internet sites, reading groups, changing patterns of literary marketing, education, employment and leisure. Academic scholarship, largely text-based, fails to engage with these public and ....The role of public culture in the construction of contemporary Australian literature. Literature is not simply a body of texts; it is a cultural technology, affected by changing patterns of production and consumption. Witness the 'cult of celebrity', the phenomenal recent growth of literary festivals, literary internet sites, reading groups, changing patterns of literary marketing, education, employment and leisure. Academic scholarship, largely text-based, fails to engage with these public and popular phenomena. Our project develops methods for describing and evaluating how these practices construct literary value and cultural identity, in ways that will bring academic literary analysis into a more informed, more creative engagement with public and popular culture in Australia.Read moreRead less
On-line monitoring of cyanobacteria to predict coagulant doses and powdered activated carbon application in water treatment. Cyanobacteria, more commonly known as blue-green algae, can impact water quality by releasing toxins that can be harmful to human health and imparting unpleasant taste and odours to the water. This project will support the water industry in managing these risks by providing a rapid, on-line tool to assist in their removal during water treatment.
More bang for your carbon buck: carbon, biodiversity and water balance consequences of whole-catchment carbon farming. Farming carbon via tree plantings on pasture land is becoming increasingly common to address the effects of climate change. This activity is likely to produce dramatic changes in Australia's rural landscapes, but we have little knowledge of likely effects on crucial ecosystem services and attributes such as stream water yields and biodiversity. This project will investigate the ....More bang for your carbon buck: carbon, biodiversity and water balance consequences of whole-catchment carbon farming. Farming carbon via tree plantings on pasture land is becoming increasingly common to address the effects of climate change. This activity is likely to produce dramatic changes in Australia's rural landscapes, but we have little knowledge of likely effects on crucial ecosystem services and attributes such as stream water yields and biodiversity. This project will investigate the relationship between tree cover, carbon uptake, water yield and biodiversity. The outcomes will allow government agencies, landowners and carbon farming groups to better evaluate the effects of different landscape planning options and contribute to effective long-term planning for multiple goals.Read moreRead less