Adaptive ecotyping of the toxic cyanobacterium Cylindrospermopsis raciborskii to predict its invasive capacity. We change the world while other organisms adapt to these new conditions. Cyanobacteria (blue green algae) increasingly dominate water bodies that were previously free of these harmful blooms. To minimise the spread of these algae, this project will study the genetic basis that determines how rapidly they can evolve and adapt to a changing planet.
Activating lazy stormwater wetlands through real time monitoring & control. Constructed stormwater wetlands are the last line of defence preventing pollution of urban waterways, but wetlands often fail, with their passive operation unable to adapt to the highly variable climate and hydrology they experience. This project aims to use advances in real-time control technology to turn these lazy wetlands into active wetland systems, optimising their performance. It aims to deliver new-generation tec ....Activating lazy stormwater wetlands through real time monitoring & control. Constructed stormwater wetlands are the last line of defence preventing pollution of urban waterways, but wetlands often fail, with their passive operation unable to adapt to the highly variable climate and hydrology they experience. This project aims to use advances in real-time control technology to turn these lazy wetlands into active wetland systems, optimising their performance. It aims to deliver new-generation technologies to enhance water quality treatment, enhance urban water security and guarantee environmental flows to maintain healthy waterways. Working in partnership with waterway managers and water retailers, this project strives to deliver a nationally and globally relevant technology to change how we manage water in cities.Read moreRead less
Smart management of disinfectant in chloraminated water-supply systems. Smart management of disinfectant in chloraminated water-supply systems. This project aims to develop an adaptive, real-time control system for managing disinfectant residuals in chloraminated water supply systems. While chloramine delivers microbiologically safe drinking water in warmer climates and in long distribution systems, it is largely unpredictable, costs water utilities millions of dollars annually, and has uncertai ....Smart management of disinfectant in chloraminated water-supply systems. Smart management of disinfectant in chloraminated water-supply systems. This project aims to develop an adaptive, real-time control system for managing disinfectant residuals in chloraminated water supply systems. While chloramine delivers microbiologically safe drinking water in warmer climates and in long distribution systems, it is largely unpredictable, costs water utilities millions of dollars annually, and has uncertain benefits. This project’s control system will be guided by quantitative models formulated from multi-pronged, fundamental experiments. The project will quantify microbial chloramine decay and determine mechanisms to increase predictability. The project will develop and demonstrate a real-time control technology which delivered microbiologically safe, cost-efficient drinking water to people in warmer climates, despite warming climate and increasing population.Read moreRead less
On-line monitoring of cyanobacteria to predict coagulant doses and powdered activated carbon application in water treatment. Cyanobacteria, more commonly known as blue-green algae, can impact water quality by releasing toxins that can be harmful to human health and imparting unpleasant taste and odours to the water. This project will support the water industry in managing these risks by providing a rapid, on-line tool to assist in their removal during water treatment.
Revolutionising water-quality monitoring in the information age. In today’s information age, automated low-cost sensors distributed in the environment have the potential to revolutionise the way we monitor and manage air, water and soil. This project aims to develop novel statistical methods to detect anomalies in the data generated from these in-situ sensors with computationally efficient modelling on river networks through space and time, with the applied goals of automating anomaly detection ....Revolutionising water-quality monitoring in the information age. In today’s information age, automated low-cost sensors distributed in the environment have the potential to revolutionise the way we monitor and manage air, water and soil. This project aims to develop novel statistical methods to detect anomalies in the data generated from these in-situ sensors with computationally efficient modelling on river networks through space and time, with the applied goals of automating anomaly detection in water-quality data and generating predictions of sediment and nutrient concentrations throughout river networks in near-real time. This will represent a fundamental increase in scientific knowledge, which will be immediately useful in the domains of aquatic science, environmental monitoring, and statistics.Read moreRead less
A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Ethical frameworks for responsible innovation of neurotechnology. This project aims to ensure the ethical and efficient innovation of emerging neurotechnologies, including implantable brain devices, synthetic drugs and direct-to-consumer brain devices. This project expects to generate Australian’s first responsible innovation framework through extensive community engagement. Expected outcomes of this project include: guidelines for the development of neurotechnologies; a national framework for r ....Ethical frameworks for responsible innovation of neurotechnology. This project aims to ensure the ethical and efficient innovation of emerging neurotechnologies, including implantable brain devices, synthetic drugs and direct-to-consumer brain devices. This project expects to generate Australian’s first responsible innovation framework through extensive community engagement. Expected outcomes of this project include: guidelines for the development of neurotechnologies; a national framework for responsible innovation; partnerships with international brain initiatives; and enhanced interdisciplinary capacity. The proposed research should provide significant benefits: innovation of technologies that meet Australians' needs, reduced misuse and harm, and greater social support for innovation in neuroscience.Read moreRead less
Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water ....Sequencing and assembling microbial community metagenomes in real-time. This project aims to assemble metagenomes directly from environmental samples using nanopore sequencing. Short-read approaches to metagenomics cannot assemble mixed genomes from an environmental sample, so focus on describing which species and genes are present. Long-read nanopore sequencing enables the assembly of full genomes of multiple species in a sample. Assembling complete genomes in important resources such as water and soil should lead to deeper understanding of the dynamics, variation and transfer of genetic material within these resources’ microbial communities, strategies to manage microbial diversity, and improved productivity and long-term sustainability for these resources.Read moreRead less
Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This pro ....Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This project aims to give policy-makers an evidence base and toolkit to determine how best to repurpose the space currently accommodating private cars. This project is expected to make cities more attractive, efficient and liveable, improving a disproportionately large number of Australian lives.Read moreRead less
Developing a national rural volunteering roadmap. This project aims to investigate the challenges affecting rural volunteering in Australia. Conducting a national analysis of volunteering demand and supply, this project expects to generate new interdisciplinary knowledge of the structural, demographic, organisational and personal factors affecting the sustainability of rural volunteering. Expected outcomes of this project include a world-first index of volunteering vulnerabilities and a spatial ....Developing a national rural volunteering roadmap. This project aims to investigate the challenges affecting rural volunteering in Australia. Conducting a national analysis of volunteering demand and supply, this project expects to generate new interdisciplinary knowledge of the structural, demographic, organisational and personal factors affecting the sustainability of rural volunteering. Expected outcomes of this project include a world-first index of volunteering vulnerabilities and a spatial map of volunteering unevenness, leading to the development of an evidence-based National Rural Volunteering Roadmap (2025-2035), which will guide our volunteering peak body partners, governments and rural communities to plan for and support rural volunteering over the longer-term.Read moreRead less