Optimising seasonal decisions for environmental water use. This project will develop a tool to optimise the use of environmental water, drawing on seasonal forecasts of streamflow and water price, and predicted ecological responses to changing flows. This tool will strengthen the effectiveness of the government organisations responsible for managing Australia's environmental water reserves.
Water availability and demand: better forecasts, better management. This project aims to improve Australia’s capability in the provision and use of water forecasts for managing water resources. The current water forecasts are not fully utilised by water agencies as they are not sufficiently comprehensive and advanced. This project expects to achieve a step change in the uptake and utility of hydro-climate forecasts through an extensive partnership of leading researchers and operational agencies ....Water availability and demand: better forecasts, better management. This project aims to improve Australia’s capability in the provision and use of water forecasts for managing water resources. The current water forecasts are not fully utilised by water agencies as they are not sufficiently comprehensive and advanced. This project expects to achieve a step change in the uptake and utility of hydro-climate forecasts through an extensive partnership of leading researchers and operational agencies of hydro-climate forecasting, with federal, state and regional water agencies.Read moreRead less
Optimising haemodynamics in complex stented arteries. This project aims to optimise the hemodynamics (blood flow) in coronary arteries with high curvatures and bifurcations. Experience has shown that the build-up of plaque — and the resulting occlusion of blood flow — tends to occur in these complex arterial regions. The most common therapeutic strategy is the insertion of a stent to prop open the artery. However, the nature of the geometry often leads to post-stenting complications such as rest ....Optimising haemodynamics in complex stented arteries. This project aims to optimise the hemodynamics (blood flow) in coronary arteries with high curvatures and bifurcations. Experience has shown that the build-up of plaque — and the resulting occlusion of blood flow — tends to occur in these complex arterial regions. The most common therapeutic strategy is the insertion of a stent to prop open the artery. However, the nature of the geometry often leads to post-stenting complications such as restenosis and thrombosis, ultimately resulting in negative outcomes. In this project, advanced research methods from fluid dynamics and optimisation and control will be used to potentially minimise these highly undesirable effects.Read moreRead less
We have discovered a single tumour factor which causes cancer cachexia, a wasting condition that is one of the worst complications of malignancy, for which there is no current effective treatment. We have developed antibodies which effectively block this condition in preclinical models and have produced human/humanised version of this. This application is to characterise these human antibodies to allow us proceed to clinical trials.
Special Research Initiatives - Grant ID: SR180100021
Funder
Australian Research Council
Funding Amount
$900,000.00
Summary
PFAS source zone remediation by foam fractionation and in situ fluidisation. This project aims to develop two methods for the in situ remediation of per- and poly-fluroalkyl substances (PFAS) contamination, downhole foam fractionation for in situ groundwater treatment, and in situ fluidisation for soil treatment, both separately and in combination. Using these methods, PFASs will be removed in the form of a foam, which will be extracted as a liquid concentrate. These techniques could enable PFAS ....PFAS source zone remediation by foam fractionation and in situ fluidisation. This project aims to develop two methods for the in situ remediation of per- and poly-fluroalkyl substances (PFAS) contamination, downhole foam fractionation for in situ groundwater treatment, and in situ fluidisation for soil treatment, both separately and in combination. Using these methods, PFASs will be removed in the form of a foam, which will be extracted as a liquid concentrate. These techniques could enable PFAS removal efficiencies of greater than 90%, providing entirely new methods for the aggressive removal of PFAS from contaminated source zones. This project will enable the rapid removal of the bulk of the PFAS present in soils and groundwater and reduce the potential for further spreading.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100047
Funder
Australian Research Council
Funding Amount
$540,000.00
Summary
A multi-frequency microwave radiometer system for environmental research. A multi-frequency microwave radiometer system for environmental research: A new capability for airborne remote sensing of key environmental variables will be established. The unique P-, Ku- and Ka-band passive microwave radiometer system will provide information on soil moisture, surface temperature and vegetation, and allow for a new satellite concept to be demonstrated. By combining with an existing L-band radiometer, da ....A multi-frequency microwave radiometer system for environmental research. A multi-frequency microwave radiometer system for environmental research: A new capability for airborne remote sensing of key environmental variables will be established. The unique P-, Ku- and Ka-band passive microwave radiometer system will provide information on soil moisture, surface temperature and vegetation, and allow for a new satellite concept to be demonstrated. By combining with an existing L-band radiometer, data can be collected simultaneously at P-, L-, Ku- and Ka-bands, with increased spatial resolutions accordingly. The shorter wavelength, but higher spatial resolution data can be used to enhance the spatial resolution of the longer wavelength data, resulting in a capability to derive long wavelength observations from space at unprecedented spatial resolution.Read moreRead less
Fundamental studies of multiphase flow and separation performance of natural medium cyclones for recovering waste coal. This project aims to develop an effective method to design, control and optimise natural medium cyclones for recovering waste coal, important for environmental protection and for energy efficiency. Its conduct will enhance Australia's leading position in the coal industry.
Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or refl ....Controlling coastlines while generating power. The Project aims to produce strategies for protecting coasts from storms using farms of wave-energy machines, which also generate electricity. Increasing lengths of coast need protection as the climate changes, but conventional barriers create permanent environmental impacts and are a sunk cost usually borne by the taxpayer. The Project expects to derive a strategy for the setting of each machine in the farm, so that they collectively absorb or reflect damaging waves under severe conditions. Under normal conditions, enough wave energy to sustain environmental processes would pass through. Sales of electricity would help to pay back the capital cost. Outcomes would include reduced coastal-erosion costs and a low-intermittency energy supply.Read moreRead less
Numerical and experimental studies of the gas-particle flow and dust collection in electrostatic precipitation systems. This project will generate an integrated computer model to describe the gas-solid flow and dust collection in an ElectroStatic Precipitator (ESP). The model can be used to aid the design and control of ESP systems which are widely used for dust collection, leading to more competitive energy and related industries.
Deadly Commute - Targeting The Trafficking Mechanisms That Licence Inflammatory Cell Death
Funder
National Health and Medical Research Council
Funding Amount
$774,544.00
Summary
MLKL is a protein naturally found inside cells. MLKL is activated by inflammation. Once activated, MLKL relocates to the outer periphery of cells and kills them. Gut cells are especially vulnerable to death-by-MLKL and this problem causes Inflammatory Bowel Disease. Using cutting edge microscopy, we have discovered how MLKL moves to the periphery of cells prior to killing them. We will test if blocking this movement of MLKL to the cell periphery stops gut death and Inflammatory Bowel Disease.