An Interdisciplinary Approach Towards Antiviral Therapy Discovery
Funder
National Health and Medical Research Council
Funding Amount
$2,000,000.00
Summary
Viruses cause significant life-threatening diseases and our armament against viral infections is extremely limited. When coupled with resistance development, humanity is at the mercy of existing and emerging life-threatening viruses. This project will provide new insight into how clinically- significant viruses that cause flu, croup and hand foot and mouth disease attack human cells, as well as discover new drug candidates that combat these viruses.
Understanding Cell Signalling As A Basis For New Therapeutics
Funder
National Health and Medical Research Council
Funding Amount
$2,231,372.00
Summary
This Investigator grant will capitalise on my extensive expertise in determining the three-dimensional atomic structures of proteins to uncover fundamental biological mechanisms in cancer and Alzheimer’s disease as a basis for discovering new drugs to combat these devastating diseases.
Harnessing Imaging And IT Strategies To Expedite Targeted Treatment And Improve Outcomes In Cerebrovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,914,215.00
Summary
This project will expand on my 25+ years of research in combining neuroimaging methods such as CT and MRI with nascent software tools to better target and coordinate treatment and achieve improved outcomes in cerebrovascular diseases such as stroke. We will develop & improve new CT and MRI methods and leverage latest advances in computer science, such as deep learning and mobile phone app technology, to achieve faster and more accurate identification of patients who can benefit from treatment.