A Randomised Controlled Trial Of Interventional Versus Conservative Treatment Of Primary Spontaneous Pneumothorax
Funder
National Health and Medical Research Council
Funding Amount
$412,315.00
Summary
Primary spontaneous pneumothorax (PSP) is a collapsed lung that occurs in otherwise healthy people without underlying lung disease. Current standard treatment is to insert a chest drain into the chest to remove the air around the collapsed lung so that the lung re-inflates rapidly ("interventional treatment"). We will determine whether doing nothing, i.e. letting the lung re-inflate slowly on its own over several weeks ("conservative treatment"), is just as good or even better for patients.
Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of profi ....Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of proficiency testing and continuing education vital for a vibrant, well regulated discipline. In addition, the project will contribute to our knowledge of the pathology assessed in the screening and diagnosis of cancers such as cervical, lung and bladder cancers.Read moreRead less
Market segmentation methodology: attacking the 'Too Hard' basket. Businesses embrace market segmentation to identify and target clients. However, poor segmentation analysis leads to poor segment choice. This project will develop tools to improve segmentation analysis and will test the resulting tools in tourism, foster care and climate change mitigating behaviours, and produce usable, transferable recommendations.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100035
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Hyperpolarised gas functional lung and molecular imaging. This project will produce a polariser to generate magnetised gas for research with magnetic resonance imaging (MRI). This allows imaging of normal and abnormal lung ventilation and circulation in animal and humans. The use of these hyperpolarised gases can also be used to tag specific molecules and increase understanding of lung metabolism.
Improved detection and characterisation of breast cancer using magnetic resonance imaging, and novel image analysis and pattern recognition techniques. Breast cancer is a leading cause of death in Australian women. With no clear cause, one mainstay of management has been early detection. Newer medical imaging technologies such as magnetic resonance imaging require complex analysis to achieve their full benefit. Should the computationally demanding analyses of these images provide more sensitive ....Improved detection and characterisation of breast cancer using magnetic resonance imaging, and novel image analysis and pattern recognition techniques. Breast cancer is a leading cause of death in Australian women. With no clear cause, one mainstay of management has been early detection. Newer medical imaging technologies such as magnetic resonance imaging require complex analysis to achieve their full benefit. Should the computationally demanding analyses of these images provide more sensitive and specific detection of early cancers, the potential reductions in morbidity and mortality from breast cancer will be of immense value. Successful implementation of the proposed project will further enhance Australia's position as a world leader in biomedical research and application of computational technologies to health problems.Read moreRead less
Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Taming the uncertainty in trajectory data. This project aims to develop effective and efficient methods to manage large scale uncertain trajectory data. It provides individuals, business, government and social groups the ability to explore significant uncertain trajectories and their patterns, for important usages in location based services, logistic, transportation and tourism.
Interaction Mining for Cyberbullying Detection on Social Networks. This project plans to build an interactive mining system to detect cyberbullying on social networks that have a large number of participants and a variety of inputs, including conversation texts, time-variant changes and user profiles. The project is designed to change the existing cyberbullying prevention services from reactive keyword filtering to proactive social interaction pattern mining. The intended outcome will enable the ....Interaction Mining for Cyberbullying Detection on Social Networks. This project plans to build an interactive mining system to detect cyberbullying on social networks that have a large number of participants and a variety of inputs, including conversation texts, time-variant changes and user profiles. The project is designed to change the existing cyberbullying prevention services from reactive keyword filtering to proactive social interaction pattern mining. The intended outcome will enable the early detection and warning of cyberbullying and approach open a new way to discover interaction patterns with a large number of participants over evolving and complex social networks.Read moreRead less
Special Research Initiatives - Grant ID: SR0567196
Funder
Australian Research Council
Funding Amount
$55,000.00
Summary
Improved early detection of breast cancer enabled by grid-computing and advanced modelling and visualisation of MR images. This project will investigate the utility of grid computing in the detection of breast cancer from magnetic resonance (MR) images. The large quantity of data acquired using MR imaging is difficult for clinicians to review and the cost of missed or incorrect detection is high. To provide rapid visualisation and assessment of the acquired data, grid computing will be used in c ....Improved early detection of breast cancer enabled by grid-computing and advanced modelling and visualisation of MR images. This project will investigate the utility of grid computing in the detection of breast cancer from magnetic resonance (MR) images. The large quantity of data acquired using MR imaging is difficult for clinicians to review and the cost of missed or incorrect detection is high. To provide rapid visualisation and assessment of the acquired data, grid computing will be used in conjunction with interactive visualisation with haptic feedback. Grid computing experience and haptic device expertise will be achieved via Swedish collaborators. The successful outcome of this project will be software for the production of 3D colour-coded breast images in which suspicious regions are highlighted and can be physically interrogated using the haptic device.Read moreRead less