Efficacy Of Prism Adaptation For Recovery Of Brain Function In Unilateral Spatial Neglect
Funder
National Health and Medical Research Council
Funding Amount
$531,690.00
Summary
Damage to the brain’s attention network causes profound impairments of visual and sensory perception. These deficits are frequently long-lasting, and are a major factor in preventing patients from regaining functional independence. This project will use a combination of behavioural and brain imaging techniques to determine whether a promising new treatment involving visual retraining can improve function and reduce perceptual impairments after unilateral brain lesions.
A Scalable Theory of Behavior Composition for Practical Engineering Models of Human Performance. Minimizing human error and maximizing human performance is a major design goal in safety critical systems. The development of methods for affordable human performance modeling has widespread applicability for evaluating user-system interfaces. The compositional method explored here has been shown to make accurate predictions reduce model development time by an order of magnitude. Large safety critica ....A Scalable Theory of Behavior Composition for Practical Engineering Models of Human Performance. Minimizing human error and maximizing human performance is a major design goal in safety critical systems. The development of methods for affordable human performance modeling has widespread applicability for evaluating user-system interfaces. The compositional method explored here has been shown to make accurate predictions reduce model development time by an order of magnitude. Large safety critical applications, such as military or air traffic control systems, would benefit greatly. The proposed work tests whether the compositional methods will scale to more complex domains. The work will be coordinated with Australian industry, academia, and government research efforts.Read moreRead less
Cancers of the skin are the most common tumours in humans, and their diagnosis and treatment impose the largest costs on Australia’s cancer budget. While much has been learned about the roles of sunlight and skin type as risk factors for skin cancer, relatively little is known about the genes conferring risk. This study will compare the genetic profiles of over 6000 patients with skin cancer to 3000 people without skin cancer to pinpoint the genes responsible for skin cancer.
Determinants and consequences of conscious visual awareness. Usually salient images can disappear from awareness without corresponding stimulus changes. This project is based on an innovative account linking such disappearances to a functional adaptation which facilitates vision in cluttered environments. Project completion will expand Australia's knowledge base, forge links between junior and senior Australian based investigators and provide excellent training opportunities. Publication of rese ....Determinants and consequences of conscious visual awareness. Usually salient images can disappear from awareness without corresponding stimulus changes. This project is based on an innovative account linking such disappearances to a functional adaptation which facilitates vision in cluttered environments. Project completion will expand Australia's knowledge base, forge links between junior and senior Australian based investigators and provide excellent training opportunities. Publication of research in top-ranking international journals will further promote Australian science abroad. Ultimately, this research will have implications for the design and implementation of artificial visual systems, which must overcome many of the same dilemmas faced by the human visual system in cluttered environments.Read moreRead less
Human Time Perception. Most human tasks require timing on a scale of tens to hundreds of milliseconds. We must judge time to produce and comprehend speech, to move about and interact with our dynamic environment, to determine causality and decode information from sensory receptors. However, the neural bases of time perception are largely unknown. This project will explore temporal phenomena to determine how and where durations, temporal order and coincidence are encoded in the human brain. Proje ....Human Time Perception. Most human tasks require timing on a scale of tens to hundreds of milliseconds. We must judge time to produce and comprehend speech, to move about and interact with our dynamic environment, to determine causality and decode information from sensory receptors. However, the neural bases of time perception are largely unknown. This project will explore temporal phenomena to determine how and where durations, temporal order and coincidence are encoded in the human brain. Project results will provide new insight into the mechanisms of time perception, with implications for disorders associated with impaired time perception, such as autism, dyslexia and schizophrenia.Read moreRead less
An Implementation Trial Of A Telephone-based Care Management Program For Patients Following Myocardial Infarction
Funder
National Health and Medical Research Council
Funding Amount
$641,656.00
Summary
We are trialling the implementation of an innovative telephone-delivered program for managing people who have had a heart attack. Cardiac rehabilitation programs are generally based in hospitals in Australia and people have to be able to attend the programs when they are offered. Even though such programs have been shown to be very effective in improving outcomes after a heart attack, at least 85% of Australians after a heart attack are either unable to access and-or unable to attend such progra ....We are trialling the implementation of an innovative telephone-delivered program for managing people who have had a heart attack. Cardiac rehabilitation programs are generally based in hospitals in Australia and people have to be able to attend the programs when they are offered. Even though such programs have been shown to be very effective in improving outcomes after a heart attack, at least 85% of Australians after a heart attack are either unable to access and-or unable to attend such programs due to transport and many other barriers. So, there is an urgent need to identify new, effective, and affordable ways of delivering cardiac rehabilitation programs to people after a heart attack. The proposed telephone-delivered program will be particularly appropriate for disadvantaged people, such as those living in rural and remote areas as well as Indigenous Australians, who do not currently have access to hospital-based cardiac rehabilitation programs. People who have had a heart attack will be recruited from three of Brisbane's largest public teaching hospitals, and will then be randomly assigned to the telephone-delivered cardiac rehabilitation program (Care Management Intervention group) or to a control or Usual Care group. The Care Management Intervention group will receive regular telephone calls from a highly qualified 'Care Manager' based at the renowned National Heart Foundation of Australia telephone support service, 'Heartline'. The Care Manager will help people to manage their heart condition and prevent the reoccurrence of further heart problems. People will also be encouraged to make necessary lifestyle and behavioural changes with the assistance of the Care Manager and some Heart Foundation educational and interactive resources to record their progress. We expect that the program or Care Management Intervention group will have better health outcomes than the control or Usual Care group at 6 and 12 months follow up.Read moreRead less
Why does time seem to drag and fly? This project aims to investigate varying perceptions about the passage of time. It is unclear if these variations reflect functional adaptations that allow fast information processing in the face of disaster or if such sensations are inferred after the events in question. Nor is it clear if such experiences are similar across individuals. The project aims to answer these questions, with long-term potential to inform artificial intelligence systems that rely on ....Why does time seem to drag and fly? This project aims to investigate varying perceptions about the passage of time. It is unclear if these variations reflect functional adaptations that allow fast information processing in the face of disaster or if such sensations are inferred after the events in question. Nor is it clear if such experiences are similar across individuals. The project aims to answer these questions, with long-term potential to inform artificial intelligence systems that rely on temporal sensitivity. The project also has potential to provide insights into conditions associated with impaired time perception-place roles.Read moreRead less
Insights from brain imaging to study the neural basis of cognition. This project aims to address a major challenge - the need for a better understanding of the basis for human cognition. Humans have a unique capacity for diverse, complex, thought and behaviour. To achieve this our brains need to rapidly and flexibly reconfigure, directing attention to different aspects of the world moment-to-moment as we think and act. The project will combine innovative analysis methods with state-of-the-art n ....Insights from brain imaging to study the neural basis of cognition. This project aims to address a major challenge - the need for a better understanding of the basis for human cognition. Humans have a unique capacity for diverse, complex, thought and behaviour. To achieve this our brains need to rapidly and flexibly reconfigure, directing attention to different aspects of the world moment-to-moment as we think and act. The project will combine innovative analysis methods with state-of-the-art neuroimaging and brain stimulation to understand how key brain regions drive this process. Insights from this project will link brain activation to behaviour, improve insights from brain imaging, and contribute a better understanding of the neural basis of cognition. Such insights can ultimately benefit the development of evidence based approaches to key areas of public concern such as health and education.Read moreRead less
Distorted Time Perceptions: Altered neural coding or decisional criteria? Human time perception is subject to systematic distortions. For instance, prolonged exposure to a movie wherein sounds lead the visual footage can result in this timing relationship seeming to be synchronous when it did not previously. As yet, it is unclear if such effects reflect altered neural processing times (in this example, visual analyses could be sped, or auditory analyses slowed), or if neural processing times are ....Distorted Time Perceptions: Altered neural coding or decisional criteria? Human time perception is subject to systematic distortions. For instance, prolonged exposure to a movie wherein sounds lead the visual footage can result in this timing relationship seeming to be synchronous when it did not previously. As yet, it is unclear if such effects reflect altered neural processing times (in this example, visual analyses could be sped, or auditory analyses slowed), or if neural processing times are unchanged, with people simply altering the decisions they make about sensory inputs. This project will determine which type of scenario is responsible for a number of distortions of human time perception. Read moreRead less
Human Vision: Predicting the present? Suppressing the past? When dealing with moving objects, how does the human brain cope with lags between exposure to retinal images depicting physical events and consequent activity in cortex? Obviously motor planning plays a role, with people reaching toward predicted locations when intercepting moving objects, but what, if any, compensation for informational delays is provided by perception? This project will explore situations wherein moving objects are er ....Human Vision: Predicting the present? Suppressing the past? When dealing with moving objects, how does the human brain cope with lags between exposure to retinal images depicting physical events and consequent activity in cortex? Obviously motor planning plays a role, with people reaching toward predicted locations when intercepting moving objects, but what, if any, compensation for informational delays is provided by perception? This project will explore situations wherein moving objects are erroneously localised and seem deformed, in order to determine if these are indicative of perception helping to compensate for informational lags. Project results will have substantial theoretical significance, pertaining to the nature of perception and conscious visual awareness.Read moreRead less