Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Nonlinear near-field nanophotonics. This project aims to develop nanostructures which employ both high intrinsic nonlinearities and high indices of refraction to create nanophotonic devices. Silicon photonics promises a technological leap forward through efficient photon-photon interactions within lossless dielectric nanoparticles. Light-controlling-light devices open new ways to control light-matter interaction at the nanoscale, which form the basis for many applications from all-optical inform ....Nonlinear near-field nanophotonics. This project aims to develop nanostructures which employ both high intrinsic nonlinearities and high indices of refraction to create nanophotonic devices. Silicon photonics promises a technological leap forward through efficient photon-photon interactions within lossless dielectric nanoparticles. Light-controlling-light devices open new ways to control light-matter interaction at the nanoscale, which form the basis for many applications from all-optical information processing to biomedical sensing. The expected outcomes will provide Australia with advanced technologies of integrated optical circuits with applications in optical communication networks, bioimaging, solar cells and quantum information technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100003
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin ....3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin modern nanoelectronics for innovative energy, nano-optical and quantum device applications. This unique equipment will facilitate breakthrough discoveries in nanomaterials, and foster collaborations amongst Australian researchers to accelerate industry in advanced nanodevice technologies.Read moreRead less
Melanotransferrin: A “Missing Link” And A Novel Pharmacological Target For Treatment
Funder
National Health and Medical Research Council
Funding Amount
$613,848.00
Summary
Despite >30 years of research, the precise function of the protein, melanotransferrin (MTf), is unknown. However, we have breakthrough evidence that MTf stimulates WNT signalling as a major driver in cancer progression. We will investigate this hypothesis, which will underpin new cancer therapies. Indeed, we designed a new class of drugs that target the WNT pathway via up-regulating the WNT inhibitor, NDRG1. This drug (DpC) inhibits MTf expression to block tumour cell growth and metastasis.
Lead-free oxide perovskites for highly efficient solar cells. This project aims to develop nanostructured lead-free oxide perovskites for solar energy applications. These materials will strengthen the future of photovoltaic technology by overcoming bandgap voltage limitations and toxicity/stability issues that plague conventional silicon-based and emerging halide perovskite-based solar cells. This project is expected to advance the rational design of solar cells based on oxide perovskites, which ....Lead-free oxide perovskites for highly efficient solar cells. This project aims to develop nanostructured lead-free oxide perovskites for solar energy applications. These materials will strengthen the future of photovoltaic technology by overcoming bandgap voltage limitations and toxicity/stability issues that plague conventional silicon-based and emerging halide perovskite-based solar cells. This project is expected to advance the rational design of solar cells based on oxide perovskites, which are efficient, high output voltage, environmentally friendly photovoltaic technology Success of the proposed programme paves the way to promote photovoltaic technology as a mainstream power generation source and a significant contributor to achieving energy, environmental and economic goals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100752
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Rational Design of Hematite Photoanodes for Solar Hydrogen Generation. Hematite (iron oxide) is a promising electrode material for photoelectrochemical hydrogen generation from water. It has low cost, good long-term stability and absorbs light efficiently. However, its use is limited by its poor electrical conductivity. This project aims to develop a novel host-guest nanostructure that exploits the beneficial light-absorption properties of hematite (the guest) but shifts the charge transport fun ....Rational Design of Hematite Photoanodes for Solar Hydrogen Generation. Hematite (iron oxide) is a promising electrode material for photoelectrochemical hydrogen generation from water. It has low cost, good long-term stability and absorbs light efficiently. However, its use is limited by its poor electrical conductivity. This project aims to develop a novel host-guest nanostructure that exploits the beneficial light-absorption properties of hematite (the guest) but shifts the charge transport function to a nanostructured transparent conductive oxide host. The project aims to produce nanostructured hematite electrodes for efficient hydrogen production from water and sunlight, thus making a significant contribution to the goal of commercially-viable storage of solar energy in the form of hydrogen.Read moreRead less
Heparin-induced Thrombocytopenia And Thrombosis: Better Understanding Of Pathogenesis And Improving Diagnosis And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$653,137.00
Summary
Heparin, a widely used drug, can cause an adverse effect which results in a fall of the platelet count and the development of serious thrombosis. This drug complication is mediated by an immune mechanism. This proposal aims to provide a better understanding of the disease mechanism. It also aims to develop a new test that will improve the diagnosis, and to produce a novel drug that will effectively suppress the immune reaction and improve the treatment.
Porous Electromaterials for Hydrogen Production and Energy Storage. This project aims to develop nanocomposite electrodes and membranes for efficient production of renewable hydrogen and the next generation of high-energy-density battery technologies. This will be accomplished by the engineering of multi-scale porous materials with tuneable electrical, chemical and morphological properties using earth abundant elements. The intended outcome is the establishment of a scalable methodology for the ....Porous Electromaterials for Hydrogen Production and Energy Storage. This project aims to develop nanocomposite electrodes and membranes for efficient production of renewable hydrogen and the next generation of high-energy-density battery technologies. This will be accomplished by the engineering of multi-scale porous materials with tuneable electrical, chemical and morphological properties using earth abundant elements. The intended outcome is the establishment of a scalable methodology for the structuring and effective integration of microporous materials in highly conductive scaffolds, achieving superior charge and molecular transport, as well as high surface activity. Broad social and economic benefits are anticipated providing new technological solutions for renewable energy storage and fuel production.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100006
Funder
Australian Research Council
Funding Amount
$1,060,000.00
Summary
Ultra-high resolution focussed ion beam facility for Western Australia. Ultra-high resolution focussed ion beam facility: An ultra-high resolution dual beam facility (incorporating ion and electron beams) will provide 3D imaging, site-specific analysis and nano-machining to a wide range of internationally recognised Australian researchers across a broad spectrum of disciplines in the geosciences, engineering, biological and physical sciences. Providing critically needed access to this world-clas ....Ultra-high resolution focussed ion beam facility for Western Australia. Ultra-high resolution focussed ion beam facility: An ultra-high resolution dual beam facility (incorporating ion and electron beams) will provide 3D imaging, site-specific analysis and nano-machining to a wide range of internationally recognised Australian researchers across a broad spectrum of disciplines in the geosciences, engineering, biological and physical sciences. Providing critically needed access to this world-class infrastructure is expected to advance international competitiveness, leading to high-impact outcomes in smart materials, nanotechnology, bioscience, and geoscience, including support for the Australian resources sector.Read moreRead less
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.