Centre Of Research Excellence In Medicines Intelligence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
The NHMRC Centre of Research Excellence in Medicines Intelligence is a co-ordinated research program that will accelerate the development and translation of evidence on prescribed medicines use and outcomes for regulators and payers. The CRE is perfectly placed to embrace the national ‘call to action’ from the Health Minister's recent announcement to establish Quality Use of Medicine Safety as a National Health Priority.
Prevention Of Complications In Type 2 Diabetes By Using ICT To Optimise Self-management
Funder
National Health and Medical Research Council
Funding Amount
$849,181.00
Summary
The impact of the diabetes epidemic on individuals and society is severe but can be reduced by improving diabetes self-management. Conducted in partnership with Diabetes Australia (Queensland, Victoria, WA) and Roche Diagnostics, this research will evaluate the 'real world' implementation of a telehealth program, already successfully trialled, which has the potential to provide a low cost and effective program to a large number of Australians with type 2 diabetes.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100003
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin ....3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin modern nanoelectronics for innovative energy, nano-optical and quantum device applications. This unique equipment will facilitate breakthrough discoveries in nanomaterials, and foster collaborations amongst Australian researchers to accelerate industry in advanced nanodevice technologies.Read moreRead less
Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the r ....Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the receptor-ligand interactions using inexpensive miniature spectrometers - radically transforming these assays. This would generate fundamental and applied knowledge of materials sciences, photonic, and biointerfaces for label-free, ultra-sensitive, and selective assays to enable future drug and diagnostics target discovery. Read moreRead less
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.
Indoor Photovoltaics Enabled by Wide-Bandgap Perovskite Quantum Dots. This project aims to develop a high-efficiency indoor photovoltaic (PV) technology to provide reliable low-cost power in the multi-billion dollar “Internet of Things” (IoT) market. There are currently no devices that meet the requirements for maximum operating efficiency under indoor illumination. We propose to solve this problem by fabricating PV cells using colloidal perovskite quantum dots that offer class-leading stability ....Indoor Photovoltaics Enabled by Wide-Bandgap Perovskite Quantum Dots. This project aims to develop a high-efficiency indoor photovoltaic (PV) technology to provide reliable low-cost power in the multi-billion dollar “Internet of Things” (IoT) market. There are currently no devices that meet the requirements for maximum operating efficiency under indoor illumination. We propose to solve this problem by fabricating PV cells using colloidal perovskite quantum dots that offer class-leading stability and band gap tunability across the required range, enabled by quantum confinement. The outcome is the development of integrated self-powered IoT devices potentially impacting Advanced Manufacturing growth in Energy, Cyber Security, Food and Agribusiness, as all of these will ultimately rely on networked smart devices.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100140
Funder
Australian Research Council
Funding Amount
$1,050,000.00
Summary
A multiple ion beam facility for microscopy and nanofabrication. This project aims to establish a powerful multiple ion beam system for nanoscience research. The demand for customised therapies, secure communication and efficient energy harvesting prompts the development of nanoscale devices that can interface and interact with the environment: nanotechnology systems with fully functional sensors, detectors, energy and data processing modules. This project would increase the ability to observe a ....A multiple ion beam facility for microscopy and nanofabrication. This project aims to establish a powerful multiple ion beam system for nanoscience research. The demand for customised therapies, secure communication and efficient energy harvesting prompts the development of nanoscale devices that can interface and interact with the environment: nanotechnology systems with fully functional sensors, detectors, energy and data processing modules. This project would increase the ability to observe and manipulate the structure of materials at the nanometre length-scale. This project is expected to boost Australia’s research capacity in nanoscience and develop materials for nanoelectronics, energy and the environment, and structural materials. These outcomes will benefit Australia’s capacity to develop advanced manufacturing industries.Read moreRead less
Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.